2020
Primary Prophylaxis to Prevent Tuberculosis Infection in Prison Inmates: A Randomized, Double-Blind, Placebo-Controlled Trial.
Dias de Oliveira R, da Silva Santos A, Reis C, de Cássia Leite A, Correia Sacchi F, de Araujo R, Dos Santos P, Rolla V, Martinez L, Andrews J, Croda J. Primary Prophylaxis to Prevent Tuberculosis Infection in Prison Inmates: A Randomized, Double-Blind, Placebo-Controlled Trial. American Journal Of Tropical Medicine And Hygiene 2020, 103: 1466-1472. PMID: 32876010, PMCID: PMC7543866, DOI: 10.4269/ajtmh.20-0110.Peer-Reviewed Original ResearchConceptsQFT conversionTB infectionSecondary outcomesPlacebo-controlled trialQuantiFERON-TB GoldFuture clinical trialsPrimary prophylaxisMiddle-income countriesPrimary outcomeTuberculosis infectionIntervention armTuberculosis incidenceControl armTrial protocolClinical trialsElevated riskInterim analysisLatent infectionCutoff pointInfectionTrialsHigher cutoffSustained conversionInternational unitsLower rates
2018
Serum vitamin D levels and risk of prevalent tuberculosis, incident tuberculosis and tuberculin skin test conversion among prisoners
Maceda EB, Gonçalves C, Andrews JR, Ko AI, Yeckel CW, Croda J. Serum vitamin D levels and risk of prevalent tuberculosis, incident tuberculosis and tuberculin skin test conversion among prisoners. Scientific Reports 2018, 8: 997. PMID: 29343733, PMCID: PMC5772514, DOI: 10.1038/s41598-018-19589-3.Peer-Reviewed Original ResearchConceptsVitamin D levelsTuberculin skin test conversionPoor vitamin D statusSkin test conversionVitamin D statusActive tuberculosisRisk of progressionCase-control studyD levelsRisk factorsTST conversionD statusCigarette smokingTest conversionSerum vitamin D levelsSubnormal vitamin D levelsMultivariable conditional logistic regressionConditional logistic regressionConsequence of diseaseIncident tuberculosisActive diseaseLatent tuberculosisPrevalent tuberculosisVitamin DBlack race
2017
Frequency of indeterminate results from an interferon-gamma release assay among HIV-infected individuals
de Oliveira S, Trajman A, Paniago A, Motta-Castro A, Ruffino-Netto A, Maciel E, Croda J, da Gloria Bonecini-Almeida M. Frequency of indeterminate results from an interferon-gamma release assay among HIV-infected individuals. Jornal Brasileiro De Pneumologia 2017, 43: 215-218. PMID: 28746533, PMCID: PMC5687953, DOI: 10.1590/s1806-37562016000000125.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultAIDS-Related Opportunistic InfectionsBrazilCD4 Lymphocyte CountCross-Sectional StudiesFeasibility StudiesFemaleHumansInfectious Disease Incubation PeriodInterferon-gamma Release TestsLatent TuberculosisMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesTuberculin TestConceptsInterferon-gamma releaseIndeterminate resultsHIV/AIDSIGRA resultsTuberculin skin test resultsMultivariate logistic regression modelTuberculin skin testSkin test resultsCost-effectiveness studiesLogistic regression modelsAdvanced immunosuppressionAdjusted ORsSkin testClinical variablesMedical recordsHigh prevalenceHigh riskPatientsIGRARoutine useKappa statisticsPLWHAAIDSRegression modelsKappa
2016
Impact of mass-screening on tuberculosis incidence in a prospective cohort of Brazilian prisoners
Paião DS, Lemos EF, Carbone AD, Sgarbi RV, Junior AL, da Silva FM, Brandão LM, dos Santos LS, Martins VS, Simionatto S, Motta-Castro AR, Pompílio MA, Urrego J, Ko AI, Andrews JR, Croda J. Impact of mass-screening on tuberculosis incidence in a prospective cohort of Brazilian prisoners. BMC Infectious Diseases 2016, 16: 533. PMID: 27716170, PMCID: PMC5048439, DOI: 10.1186/s12879-016-1868-5.Peer-Reviewed Original ResearchConceptsTuberculin skin testingActive tuberculosisRisk factorsSubsequent diseaseProspective cohort studyEarly case detectionHigh transmission settingsHigh-risk populationPotential risk factorsProportional hazards modelSubsequent disease riskMass screening interventionTST conversionCohort studyProspective cohortHIV testingTuberculosis infectionScreening interventionsSkin testingTB notificationsTuberculosis incidenceSubsequent riskCase detectionSputum samplesActive screening
2015
Active and latent tuberculosis in Brazilian correctional facilities: a cross-sectional study
Carbone Ada S, Paião DS, Sgarbi RV, Lemos EF, Cazanti RF, Ota MM, Junior AL, Bampi JV, Elias VP, Simionatto S, Motta-Castro AR, Pompílio MA, de Oliveira SM, Ko AI, Andrews JR, Croda J. Active and latent tuberculosis in Brazilian correctional facilities: a cross-sectional study. BMC Infectious Diseases 2015, 15: 24. PMID: 25608746, PMCID: PMC4307675, DOI: 10.1186/s12879-015-0764-8.Peer-Reviewed Original ResearchConceptsLatent tuberculosis infectionPrevalence of LTBITuberculin skin testActive TBLTBI prevalenceWeeks of symptomsHigh transmission settingsCross-sectional studyPopulation-based samplePoisson regression modelsDuration of incarcerationHierarchical Poisson regression modelActive diseaseTB infectionLatent tuberculosisTB casesHIV testingSputum cultureTuberculosis infectionPoint prevalenceSkin testTuberculosis incidenceRisk factorsMultivariable modelSputum samples
2013
Impact of Latent Infection Treatment in Indigenous Populations
Yuhara L, Sacchi F, Croda J. Impact of Latent Infection Treatment in Indigenous Populations. PLOS ONE 2013, 8: e71201. PMID: 23936264, PMCID: PMC3729554, DOI: 10.1371/journal.pone.0071201.Peer-Reviewed Original ResearchConceptsSmear-positive index casesTuberculin skin testActive tuberculosisLatent infectionIndex caseInfection treatmentLatent tuberculosisActive diseaseTuberculosis contactsRetrospective studySkin testClinical recordsRisk factorsNotification databaseMultidisciplinary teamClose contactTuberculosisInfectionTreatmentAgeEstimated numberPresent studyMorbidityIndigenous BraziliansCasesActive and latent tuberculosis in prisoners in the Central-West Region of Brazil
Estevan A, de Oliveira S, Croda J. Active and latent tuberculosis in prisoners in the Central-West Region of Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2013, 46: 515-518. PMID: 23904084, DOI: 10.1590/0037-8682-1441-2013.Peer-Reviewed Original Research