Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory
Bosch L, Bosch B, De Boeck K, Nawrot T, Meyts I, Vanneste D, Le Bourlegat C, Croda J, da Silva Filho L. Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory. BMC Infectious Diseases 2017, 17: 340. PMID: 28499359, PMCID: PMC5429554, DOI: 10.1186/s12879-017-2448-z.Peer-Reviewed Original ResearchConceptsCystic fibrosisCommon fatal genetic diseaseMellitus type 2Mycobacterium tuberculosis infectionAIDS incidence ratesTuberculosis infectionTB incidenceMtb infectionTuberculosis incidenceIncidence rateSmoking dataType 2Fatal genetic diseaseRelative protectionCF carriersConfoundersMonthly incomeInfectionIncidenceNegative correlationSpatial epidemiologyGenetic diseasesFibrosisEvolutionary selective advantageTuberculosis