A review of the relationship between proinflammatory cytokines and major depressive disorder
Young J, Bruno D, Pomara N. A review of the relationship between proinflammatory cytokines and major depressive disorder. Journal Of Affective Disorders 2014, 169: 15-20. PMID: 25128861, DOI: 10.1016/j.jad.2014.07.032.Peer-Reviewed Original ResearchConceptsMajor depressive disorderProinflammatory cytokinesDepressive disorderCytokine profileSerum levelsIL-6IL-8 serum levelsHeterogeneity of MDDAnti-inflammatory treatmentPathogenesis of depressionAnti-inflammatory therapyElevated proinflammatory cytokinesElevated serum levelsProgression of MDDDevelopment of biomarkersInflammatory hypothesisMDD treatmentCSF levelsDepression medicationsMCP-1Inflammatory processMDD pathogenesisDepressed patientsPossible diagnostic toolAdjuvant properties