1996
Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age
Bahado-Singh R, Deren Ö, Tan A, D'Ancona R, Hunter D, Copel J, Mahoney M. Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age. American Journal Of Obstetrics And Gynecology 1996, 175: 1563-1568. PMID: 8987942, DOI: 10.1016/s0002-9378(96)70107-2.Peer-Reviewed Original ResearchConceptsAdvanced maternal ageMaternal ageDown syndromeNormal ultrasonographyUltrasonography resultsAbdominal circumferenceNuchal thicknessAnatomic defectsChromosomal defectsSmaller abdominal circumferenceChoroid plexus cystsFetal Down syndromeReceiver operator characteristic curveStepwise logistic regressionAbnormal ultrasonography resultsBasis of ageDown syndrome detectionUltrasonographic resultsNormal groupChromosome defectsBiparietal diameterRisk tablesTrisomy 21SyndromeShort humerusRisk of Down syndrome and any clinically significant chromosome defect in pregnancies with abnormal triple-screen and normal targeted ultrasonographic results
Bahado-Singh R, Tan A, Deren O, Hunter D, Copel J, Mahoney M. Risk of Down syndrome and any clinically significant chromosome defect in pregnancies with abnormal triple-screen and normal targeted ultrasonographic results. American Journal Of Obstetrics And Gynecology 1996, 175: 824-829. PMID: 8885729, DOI: 10.1016/s0002-9378(96)80006-8.Peer-Reviewed Original Research
1991
Congenital Heart Disease and Fetal Thoracoabdominal Anomalies: Associations in Utero and the Importance of Cytogenetic Analysis
Fogel M, Copel J, Cullen M, Hobbins J, Kleinman C. Congenital Heart Disease and Fetal Thoracoabdominal Anomalies: Associations in Utero and the Importance of Cytogenetic Analysis. American Journal Of Perinatology 1991, 8: 411-416. PMID: 1839950, DOI: 10.1055/s-2007-999427.Peer-Reviewed Original ResearchConceptsCongenital heart diseasePosterior diaphragmatic herniaDuodenal atresiaHeart diseaseExtracardiac malformationsDiaphragmatic herniaFetal echocardiographyNormal cardiac structureFetal echocardiogramMost fetusesPrenatal evaluationAbnormal karyotypeCardiac structureCytogenetic abnormalitiesFetusesAtresiaOmphaloceleNormal karyotypeAbnormalitiesDiseaseEchocardiographyGastroschisisHerniaPrenatal diagnosisMalformationsHypoplastic left heart syndrome: Prenatal diagnosis, clinical profile, and management
Blake D, Copel J, Kleinman C. Hypoplastic left heart syndrome: Prenatal diagnosis, clinical profile, and management. American Journal Of Obstetrics And Gynecology 1991, 165: 529-534. PMID: 1892177, DOI: 10.1016/0002-9378(91)90279-z.Peer-Reviewed Original ResearchMeSH KeywordsChromosome AberrationsChromosome DisordersDiagnostic ErrorsFemaleHeart Defects, CongenitalHumansPregnancyPregnancy OutcomeUltrasonography, PrenatalConceptsClinical profileExtracardiac malformationsLethal congenital heart defectNeonatal intensive care settingHypoplastic left heart syndromePrenatal diagnosisIntensive care settingCongenital heart defectsPostnatal interventionsDepth counselingHeart syndromeFetal echocardiographyCare settingsNeonatal assessmentUtero diagnosisHeart defectsElective abortionInformed consentPregnancyDiagnosisAssociated geneticMalformationsComplete evaluationInterventionCounseling
1986
Congenital heart disease and extracardiac anomalies: Associations and indications for fetal echocardiography
Copel J, Pilu G, Kleinman C. Congenital heart disease and extracardiac anomalies: Associations and indications for fetal echocardiography. American Journal Of Obstetrics And Gynecology 1986, 154: 1121-1132. PMID: 2939723, DOI: 10.1016/0002-9378(86)90773-8.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal MusclesAbnormalities, Drug-InducedAbnormalities, MultipleCentral Nervous SystemChromosome AberrationsChromosome DisordersCongenital AbnormalitiesDigestive System AbnormalitiesEchocardiographyFemaleFetal HeartHeart Defects, CongenitalHumansInfant, NewbornPhenylketonuriasPregnancyPregnancy ComplicationsPregnancy in DiabeticsPrenatal DiagnosisRespiratory System AbnormalitiesUrogenital AbnormalitiesConceptsCongenital heart diseaseHeart diseaseExtracardiac anomaliesFetal echocardiographyCardiac evaluationMaternal diabetesNeonatal managementDiaphragmatic herniaDuodenal atresiaPediatric literatureRenal dysplasiaCorpus callosumDifferential diagnosisEsophageal atresiaMeckel-Gruber syndromeReported associationsEchocardiographyPrenatal identificationSystemic defectsDiseaseAtresiaCoexistent defectsAssociationIndicationsDiabetes