2019
Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions
Tuzovic L, Copel JA, Stitelman DH, Levit O, Bahtiyar MO. Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions. Journal Of Ultrasound In Medicine 2019, 38: 2361-2372. PMID: 30653685, DOI: 10.1002/jum.14931.Peer-Reviewed Original ResearchConceptsAbnormal cardiac axisNegative predictive valueFetal cardiac axisNeonatal respiratory morbidityRespiratory morbidityCongenital lung lesionsCardiac positionPositive predictive valuePredictive valueCardiac axisLung lesionsHigh negative predictive valueSevere respiratory morbidityRetrospective cohort studyRight-sided lesionsNormal cardiac axisCohort studyWeeks' gestationMorbidityCP assessmentWeeksDiagnostic performanceLesionsPatientsGestation
1999
The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction
Bahado-Singh R, Kovanci E, Jeffres A, Oz U, Deren O, Copel J, Mari G. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. American Journal Of Obstetrics And Gynecology 1999, 180: 750-756. PMID: 10076158, DOI: 10.1016/s0002-9378(99)70283-8.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionDoppler cerebroplacental ratioPerinatal outcomesCerebroplacental ratioBirth weightGrowth restrictionDoppler examinationUmbilical artery pulsatility index valuesStepwise logistic regression analysisAbnormal cerebroplacental ratioBrain-sparing effectLast Doppler examinationUmbilical artery DopplerUmbilical artery velocimetryPulsatility index valuesReceiver operator curve characteristicsReceiver operator characteristic curveLogistic regression analysisRegression analysisArtery DopplerPerinatal morbidityPerinatal complicationsWeeks' gestationNormal medianPerinatal problems
1998
Accurate detection of anomalies by routine ultrasonography in an indigent clinic population
Magriples U, Copel J. Accurate detection of anomalies by routine ultrasonography in an indigent clinic population. American Journal Of Obstetrics And Gynecology 1998, 179: 978-981. PMID: 9790383, DOI: 10.1016/s0002-9378(98)70201-7.Peer-Reviewed Original ResearchConceptsVentricular septal defectScreening ultrasonographyRoutine ultrasonographyClinic populationSeptal defectRoutine screening ultrasonographyImmediate neonatal periodTermination of pregnancyPositive predictive valueMisshapen earsNeonatal chartsExtralobar sequestrationGroup of sonographersWeeks' gestationGreat arteriesNeonatal periodRetrospective studyResident clinicUltrasonographic resultsImperforate anusIndigent populationObstetric ultrasonographyFetal monitoringUltrasonographyPredictive valueAn alternative for women initially declining genetic amniocentesis: Individual Down syndrome odds on the basis of maternal age and multiple ultrasonographic markers
Bahado-Singh R, Deren O, Oz U, Tan A, Hunter D, Copel J, Mahoney M. An alternative for women initially declining genetic amniocentesis: Individual Down syndrome odds on the basis of maternal age and multiple ultrasonographic markers. American Journal Of Obstetrics And Gynecology 1998, 179: 514-519. PMID: 9731862, DOI: 10.1016/s0002-9378(98)70388-6.Peer-Reviewed Original ResearchConceptsHyperechoic fetal bowelMaternal ageDown syndromeFetal bowelUltrasonographic parametersScreen-positive rateSignificant independent predictorsAge-related riskDown syndrome riskIndividual oddsLikelihood ratioPositive predictive valueHypoplastic fifth digitDigit hypoplasiaWeeks' gestationIndependent predictorsNormal medianIndividual Down syndrome oddsSingleton fetusesSyndrome riskUltrasonographic markersSerum screeningGenetic amniocentesisHigh riskNuchal thickeningGlycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia
Hsu C, Hong S, Nickless N, Copel J. Glycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia. American Journal Of Perinatology 1998, 15: 199-202. PMID: 9572378, DOI: 10.1055/s-2007-993926.Peer-Reviewed Original ResearchConceptsIDDM pregnant womenMean HbA1c valuesIncidence of preeclampsiaHbA1c valuesPregnant womenGestational periodExact testInsulin-dependent diabetes mellitusHigher mean HbA1cPathogenesis of preeclampsiaWeeks of gestationFisher's exact testDifferent gestational periodsNormal mean valueIDDM pregnanciesMean HbA1cDiabetes mellitusWeeks' gestationGlycosylated hemoglobinInsulin-DependentRetrospective studyTrophoblastic invasionMedical recordsPreeclampsiaHigh incidence
1997
Prenatal sonographic findings in 187 fetuses with Down syndrome
Rotmensch S, Liberati M, Bronshtein M, Schoenfeld‐Dimaio M, Shalev J, Ben‐Rafael Z, Copel J. Prenatal sonographic findings in 187 fetuses with Down syndrome. Prenatal Diagnosis 1997, 17: 1001-1009. PMID: 9399347, DOI: 10.1002/(sici)1097-0223(199711)17:11<1001::aid-pd186>3.0.co;2-x.Peer-Reviewed Original ResearchConceptsDown syndrome fetusesSonographic findingsSyndrome fetusesFetal karyotypeDown syndromeNuchal fold thicknessAbnormal sonographic findingsInternal organ abnormalitiesPrenatal sonographic findingsDown syndrome detectionEchogenic bowelWeeks' gestationUltrasound scanSame fetusCystic hygromaCardiac defectsConcurrent malformationsFold thicknessStructural abnormalitiesOrgan abnormalitiesFetusesSyndromeAbnormalitiesSyndrome detectionGestationFirst-trimester growth restriction and fetal aneuploidy: The effect of type of aneuploidy and gestational age
Bahado-Singh R, Lynch L, Deren O, Morroti R, Copel J, Mahoney M, Williams J. First-trimester growth restriction and fetal aneuploidy: The effect of type of aneuploidy and gestational age. American Journal Of Obstetrics And Gynecology 1997, 176: 976-980. PMID: 9166154, DOI: 10.1016/s0002-9378(97)70388-0.Peer-Reviewed Original ResearchConceptsCrown-rump lengthGestational ageTrisomy 18First trimester fetal growthFirst-trimester crown-rump lengthLength shorteningFirst-trimester growth restrictionLast menstrual periodReceiver operator characteristic curveFirst-trimester fetusesPrenatal diagnosis centerWeeks' gestationRisk pregnanciesFetal growthAneuploidy riskControl fetusesGrowth restrictionMenstrual periodNormal groupNormal fetusesTrimester fetusesAneuploid fetusesTrisomy 21Trisomy 13Down syndrome
1996
Is the fetal brain‐sparing effect a risk factor for the development of intraventricular hemorrhage in the preterm infant?
Mari G, Abuhamad A, Keller M, Verpairojkit B, Ment L, Copel J. Is the fetal brain‐sparing effect a risk factor for the development of intraventricular hemorrhage in the preterm infant? Ultrasound In Obstetrics And Gynecology 1996, 8: 329-332. PMID: 8978007, DOI: 10.1046/j.1469-0705.1996.08050329.x.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery pulsatility indexCerebral artery pulsatility indexBrain-sparing effectArtery pulsatility indexIntrauterine growth restrictionIntraventricular hemorrhagePulsatility indexPreterm laborAntenatal exposureGestational ageMean birth weightNeonatal intraventricular hemorrhageRespiratory distress syndromeMiddle cerebral arteryFirst postnatal weekApgar scoreCesarean sectionNecrotizing enterocolitisPreterm infantsBrain sparingDistress syndromeWeeks' gestationCerebral arteryIUGR fetusesDoppler studies
1995
Abdominal venous system in the normal fetus.
Mari G, Uerpairojkit B, Copel J. Abdominal venous system in the normal fetus. Obstetrics And Gynecology 1995, 86: 729-33. PMID: 7566838, DOI: 10.1016/0029-7844(95)00264-r.Peer-Reviewed Original ResearchConceptsFlow velocity waveformsInferior vena cavaAbdominal venous systemUmbilical sinusNormal fetusesVena cavaPortal veinVenous systemVelocity waveformsDuctus venosusSplenic veinHepatic veinUmbilical veinCommon iliac veinLeft hepatic veinAdrenal veinWeeks' gestationRenal veinIliac veinAnterior divisionPosterior divisionMonophasic patternFetusesCavaBiphasic patternUmbilical artery flow velocity waveforms in monoamniotic twins with cord entanglement.
Abuhamad A, Mari G, Copel J, Cantwell C, Evans A. Umbilical artery flow velocity waveforms in monoamniotic twins with cord entanglement. Obstetrics And Gynecology 1995, 86: 674-7. PMID: 7675410, DOI: 10.1016/0029-7844(95)00210-i.Peer-Reviewed Case Reports and Technical NotesConceptsUmbilical artery velocity waveformsFlow velocity waveformsCord entanglementMonoamniotic twinsVelocity waveformsUltrasonographic evidenceWeeks' gestationUmbilical artery flow velocity waveformsDoppler flow velocity waveformsMiddle cerebral arteryFetal-placental circulationTwin membersUmbilical cord entanglementAntepartum managementDoppler findingsCerebral arteryHemodynamic alterationsAntepartum periodUmbilical vesselsGestationPregnancyArteryFetusesNormal nuchal thickness inthe midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results
Bahado-Singh R, Goldstein I, Uerpairojkit B, Copel J, Mahoney M, Baumgarten A. Normal nuchal thickness inthe midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results. American Journal Of Obstetrics And Gynecology 1995, 173: 1106-1110. PMID: 7485301, DOI: 10.1016/0002-9378(95)91334-3.Peer-Reviewed Original ResearchConceptsAbnormal triple-screen resultsTriple-screen resultsNuchal thicknessDown syndromeHuman chorionic gonadotropin levelsNuchal thickness measurementChorionic gonadotropin levelsReceiver operator characteristic curveNumber of amniocentesesReceiver operator characteristic plotsRisk thresholdMidtrimester pregnancyGonadotropin levelsWeeks' gestationMaternal ageConsecutive fetusesUnconjugated estriolSerum screeningEuploid fetusesAlpha-fetoproteinSyndromeTrisomy 21Screen resultsRisk estimatesFetusesFifth digit measurement in normal pregnancies: a potential sonographic sign of Down's syndrome
Goldstein I, Gomez K, Copel J. Fifth digit measurement in normal pregnancies: a potential sonographic sign of Down's syndrome. Ultrasound In Obstetrics And Gynecology 1995, 5: 34-37. PMID: 7850587, DOI: 10.1046/j.1469-0705.1995.05010034.x.Peer-Reviewed Original ResearchConceptsGestational ageFifth fingerBiparietal diameterDown syndromeFemoral lengthHumeral lengthRoutine biometric measurementsNormal pregnancyWeeks' gestationStudy groupSonographic signsNormal fetusesSyndromePrenatal detectionFurther studiesGestationAgeNormative dataFetusesBiometric measurementsFingerLinear growthDigit measurementsPregnancy
1994
Growth of the fetal gall bladder in normal pregnancies
Goldstein I, Tamir A, Weisman A, Jakobi P, Copel J. Growth of the fetal gall bladder in normal pregnancies. Ultrasound In Obstetrics And Gynecology 1994, 4: 289-293. PMID: 12797163, DOI: 10.1046/j.1469-0705.1994.04040289.x.Peer-Reviewed Original ResearchFetal gall bladderGestational ageGall bladderAbdominal circumferenceBiparietal diameterBladder areaFirst-degree correlationGall-bladder areaFemoral lengthNormal pregnant womenBiliary duct systemSignificant correlationRoutine biometric measurementsNormative dataBladder circumferenceNormal pregnancyWeeks' gestationPregnant womenAdditional lesionsStudy groupBladderCircumferenceLong bonesAgeFurther studiesThe real-time and color Doppler appearance of adrenal neuroblastoma in a third-trimester fetus.
Goldstein I, Gomez K, Copel J. The real-time and color Doppler appearance of adrenal neuroblastoma in a third-trimester fetus. Obstetrics And Gynecology 1994, 83: 854-6. PMID: 8159375.Peer-Reviewed Case Reports and Technical NotesConceptsDoppler flow studiesCommon malignant tumorColor Doppler appearanceThird-trimester fetusesFlow mappingColor flow mappingFetal neuroblastomaAdrenal neuroblastomaWeeks' gestationUltrasound evaluationRenal poleDoppler appearanceMalignant tumorsColor DopplerUse of ultrasoundPrenatal recognitionNeuroblastomaGestationTumorsFlow studiesUltrasonographyFetusesDiagnosisWomen
1993
Erythropoietin in human fetuses with immune hemolytic anemia and hydrops fetalis.
Moya F, Grannum P, Widness J, Clemons G, Copel J, Hobbins J. Erythropoietin in human fetuses with immune hemolytic anemia and hydrops fetalis. Obstetrics And Gynecology 1993, 82: 353-8. PMID: 8355933.Peer-Reviewed Original ResearchConceptsRh isoimmunizationGestational agePlasma erythropoietinWeeks' gestationElective cesareanControl fetusesImmune hemolytic anemiaUmbilical cord plasmaHigh erythropoietin levelsUmbilical cord bloodCord plasmaLower hemoglobinInverse associationTerm fetusesCord bloodErythropoietin levelsHemolytic anemiaErythropoietin measurementsLate gestationHuman fetusesGestationFetusesIsoimmunizationAnemiaHemoglobin
1992
Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination
Bahado-Singh R, Wyse L, Dorr M, Copel J, O'Connor T, Hobbins J. Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination. American Journal Of Obstetrics And Gynecology 1992, 167: 1009-1014. PMID: 1415385, DOI: 10.1016/s0002-9378(12)80029-9.Peer-Reviewed Original ResearchConceptsDown syndrome fetusesSyndrome fetusesFrontothalamic distanceDown syndromePositive predictive valueWeeks' gestationGestational ageNormal medianPosterior thalamusUltrasonographic examinationGroup 52Normal fetusesFrontal lobePredictive valueInner tableFetusesFrontal boneMedianGestationMean valueSyndrome
1991
Foramen ovale size in the normal and abnormal human fetal heart: an indicator of transatrial flow physiology
Feit L, Copel J, Kleinman C. Foramen ovale size in the normal and abnormal human fetal heart: an indicator of transatrial flow physiology. Ultrasound In Obstetrics And Gynecology 1991, 1: 313-319. PMID: 12797035, DOI: 10.1046/j.1469-0705.1991.01050313.x.Peer-Reviewed Original ResearchHeart obstructive lesionsLeft heart obstructive lesionsObstructive lesionsColor Doppler studyDoppler studiesForamen ovaleColor flow Doppler studiesNormal cardiac anatomyCongenital heart diseaseRight ventricular developmentNormal flow patternsHuman fetal heartWeeks' gestationVentricular sizeDoppler interrogationFetal echocardiographyHeart diseaseAtrial septumHelpful adjunctNormal fetusesHuman fetusesFetal heartLesionsFetusesCardiac anatomyCan umbilical artery pulsatility index predict the outcome of fetuses with structural heart disease?
Copel J, Hobbins J, Kleinman C. Can umbilical artery pulsatility index predict the outcome of fetuses with structural heart disease? Journal Of Ultrasound In Medicine 1991, 10: 323-326. PMID: 1895374, DOI: 10.7863/jum.1991.10.6.323.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseElevated pulsatility indexPulsatility indexHeart diseaseUmbilical artery PI valuesUmbilical artery pulsatility indexUmbilical artery Doppler waveformsNormal PI valuesArtery pulsatility indexOutcome of fetusesStructural heart diseaseEnd-diastolic velocityWeeks' gestationFatal anomalyCHD fetusesAnomalous fetusesDoppler waveformsFatal diseaseFetusesNormal populationDiseasePI valuesGestationNormal chromosomesLesionsFetal echocardiography in multiple gestations
Copel J, Inati M, Green J, Hobbins J, Keinman C. Fetal echocardiography in multiple gestations. Ultrasound In Obstetrics And Gynecology 1991, 1: 111-114. PMID: 12797084, DOI: 10.1046/j.1469-0705.1991.01020111.x.Peer-Reviewed Original ResearchMultiple gestationsHeart diseaseSets of twinsFetal echocardiographyFetal cardiac defectsMaternal digitalizationWeeks' gestationCongestive failureExtracardiac malformationsCardiac anomaliesFetal echocardiogramLocation of deliveryAnomalous fetusesPatient managementCardiac defectsSets of tripletsGestationKaryotypic abnormalitiesFetusesDiseaseEchocardiographyEchocardiogramPatientsPregnancyAbnormalities
1989
Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion
Copel J, Grannum P, Green J, Belanger K, Hanna N, Jaffe C, Hobbins J, Kleinman C. Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion. American Journal Of Obstetrics And Gynecology 1989, 161: 361-365. PMID: 2504042, DOI: 10.1016/0002-9378(89)90520-6.Peer-Reviewed Original ResearchConceptsCardiac outputAnemic fetusesIsoimmunized pregnanciesCombined ventricular outputDoppler echocardiographic studyFetal cardiac outputHigh output stateHigh cardiac outputIntravascular intrauterine transfusionSevere isoimmunizationCardiac indexIntrauterine transfusionIntravascular transfusionWeeks' gestationVentricular outputDoppler assessmentAge-specific normsControl fetusesHydrops fetalisControl groupMechanisms of developmentFetusesUnaffected fetusesTransfusionPregnancy