2018
An atypical case of megacystis microcolon intestinal hypoperistalsis syndrome with extended survival and consistent bowel function
Farrelly J, Weiss R, Copel J, Porto A, Ahle S, Luks V, McGrath J, Stitelman D. An atypical case of megacystis microcolon intestinal hypoperistalsis syndrome with extended survival and consistent bowel function. Journal Of Pediatric Surgery Case Reports 2018, 30: 48-51. DOI: 10.1016/j.epsc.2017.11.010.Peer-Reviewed Case Reports and Technical Notes
1998
New triple screen test for down syndrome: Combined urine analytes and serum AFP
Bahado-Singh R, Oz U, Kovanci E, Cermik D, Flores D, Copel J, Mahoney M, Cole L. New triple screen test for down syndrome: Combined urine analytes and serum AFP. The Journal Of Maternal-Fetal Medicine 1998, 7: 111-114. DOI: 10.3109/14767059809020424.Peer-Reviewed Original ResearchSerum AFPIndividual Down syndrome oddsMaternal ageTriple screenDown syndromeTriple testTriple screen testΒ-core fragmentDown syndrome casesNeural tube defectsDown's syndrome likelihood ratiosEstriol levelsLarge trialsSecond trimesterUrine testsPositive rateEstriol ratioSyndrome casesTube defectsScreen testFalse positive rateAFP dataUrine analytesAFPSyndrome
1997
Prenatal sonographic findings in 187 fetuses with Down syndrome
Rotmensch S, Liberati M, Bronshtein M, Schoenfeld‐Dimaio M, Shalev J, Ben‐Rafael Z, Copel J. Prenatal sonographic findings in 187 fetuses with Down syndrome. Prenatal Diagnosis 1997, 17: 1001-1009. PMID: 9399347, DOI: 10.1002/(sici)1097-0223(199711)17:11<1001::aid-pd186>3.0.co;2-x.Peer-Reviewed Original ResearchConceptsDown syndrome fetusesSonographic findingsSyndrome fetusesFetal karyotypeDown syndromeNuchal fold thicknessAbnormal sonographic findingsInternal organ abnormalitiesPrenatal sonographic findingsDown syndrome detectionEchogenic bowelWeeks' gestationUltrasound scanSame fetusCystic hygromaCardiac defectsConcurrent malformationsFold thicknessStructural abnormalitiesOrgan abnormalitiesFetusesSyndromeAbnormalitiesSyndrome detectionGestation
1996
Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age
Bahado-Singh R, Deren Ö, Tan A, D'Ancona R, Hunter D, Copel J, Mahoney M. Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age. American Journal Of Obstetrics And Gynecology 1996, 175: 1563-1568. PMID: 8987942, DOI: 10.1016/s0002-9378(96)70107-2.Peer-Reviewed Original ResearchConceptsAdvanced maternal ageMaternal ageDown syndromeNormal ultrasonographyUltrasonography resultsAbdominal circumferenceNuchal thicknessAnatomic defectsChromosomal defectsSmaller abdominal circumferenceChoroid plexus cystsFetal Down syndromeReceiver operator characteristic curveStepwise logistic regressionAbnormal ultrasonography resultsBasis of ageDown syndrome detectionUltrasonographic resultsNormal groupChromosome defectsBiparietal diameterRisk tablesTrisomy 21SyndromeShort humerus
1995
Normal nuchal thickness inthe midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results
Bahado-Singh R, Goldstein I, Uerpairojkit B, Copel J, Mahoney M, Baumgarten A. Normal nuchal thickness inthe midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results. American Journal Of Obstetrics And Gynecology 1995, 173: 1106-1110. PMID: 7485301, DOI: 10.1016/0002-9378(95)91334-3.Peer-Reviewed Original ResearchConceptsAbnormal triple-screen resultsTriple-screen resultsNuchal thicknessDown syndromeHuman chorionic gonadotropin levelsNuchal thickness measurementChorionic gonadotropin levelsReceiver operator characteristic curveNumber of amniocentesesReceiver operator characteristic plotsRisk thresholdMidtrimester pregnancyGonadotropin levelsWeeks' gestationMaternal ageConsecutive fetusesUnconjugated estriolSerum screeningEuploid fetusesAlpha-fetoproteinSyndromeTrisomy 21Screen resultsRisk estimatesFetusesFifth digit measurement in normal pregnancies: a potential sonographic sign of Down's syndrome
Goldstein I, Gomez K, Copel J. Fifth digit measurement in normal pregnancies: a potential sonographic sign of Down's syndrome. Ultrasound In Obstetrics And Gynecology 1995, 5: 34-37. PMID: 7850587, DOI: 10.1046/j.1469-0705.1995.05010034.x.Peer-Reviewed Original ResearchConceptsGestational ageFifth fingerBiparietal diameterDown syndromeFemoral lengthHumeral lengthRoutine biometric measurementsNormal pregnancyWeeks' gestationStudy groupSonographic signsNormal fetusesSyndromePrenatal detectionFurther studiesGestationAgeNormative dataFetusesBiometric measurementsFingerLinear growthDigit measurementsPregnancy
1992
Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination
Bahado-Singh R, Wyse L, Dorr M, Copel J, O'Connor T, Hobbins J. Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination. American Journal Of Obstetrics And Gynecology 1992, 167: 1009-1014. PMID: 1415385, DOI: 10.1016/s0002-9378(12)80029-9.Peer-Reviewed Original ResearchConceptsDown syndrome fetusesSyndrome fetusesFrontothalamic distanceDown syndromePositive predictive valueWeeks' gestationGestational ageNormal medianPosterior thalamusUltrasonographic examinationGroup 52Normal fetusesFrontal lobePredictive valueInner tableFetusesFrontal boneMedianGestationMean valueSyndrome
1986
Antenatal diagnosis and obstetric management of Dandy-Walker syndrome.
Pilu G, Romero R, De Palma L, Rizzo N, Jeanty P, Copel J, Bovicelli L, Hobbins J. Antenatal diagnosis and obstetric management of Dandy-Walker syndrome. The Journal Of Reproductive Medicine 1986, 31: 1017-22. PMID: 3543341.Peer-Reviewed Original ResearchConceptsDandy-Walker syndromeFetal neural axisPosterior fossa cystTermination of pregnancyReal-time ultrasound equipmentObstetric managementThird trimesterCongenital hydrocephalusFourth ventricleCerebellar vermisAntenatal diagnosisNeural axisNeurosurgical careOccipital meningoceleMajor causeDiagnosisSyndromeUltrasound equipmentTrimesterHydrocephalusPregnancyMeningoceleCasesVentricleVermis
1985
Hermansky-Pudlak syndrome in pregnancy: Two case studies
Reiss R, Copel J, Roberts N, Hobbins J. Hermansky-Pudlak syndrome in pregnancy: Two case studies. American Journal Of Obstetrics And Gynecology 1985, 153: 564-565. PMID: 4061519, DOI: 10.1016/0002-9378(85)90475-2.Peer-Reviewed Case Reports and Technical Notes