2022
NAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone
Sunderji S, Peyvandi S, Jaeggi E, Szwast A, Ryan G, Tessier F, Siddiqui S, Cuneo B, Sheth S, Treadwell M, Frommelt M, Turan S, Copel J, Emery S, Rand L, Moon-Grady AJ, Network F. NAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone. The Journal Of Maternal-Fetal & Neonatal Medicine 2022, 35: 9263-9270. PMID: 35014577, DOI: 10.1080/14767058.2022.2025536.Peer-Reviewed Original ResearchConceptsPositive pregnanciesPrimary outcomePregnancy complicationsPregnancy outcomesPremature deliverySecondary outcomesNorth American Fetal Therapy Network (NAFTNet) centersRo/SSA-positive pregnanciesRetrospective multi-center cohort studyAnti-Ro/SSAMulti-center cohort studyFetal heart blockOverall pregnancy complicationsBetter pregnancy outcomesPoor pregnancy outcomesUse of dexamethasoneTerms of efficacyHigh rateFetal dyadsMaternal comorbiditiesAntibody positivityExpectant managementMaternal diseaseNeonatal morbidityPreterm delivery
1995
Successful in utero therapy of fetal heart block
Copel J, Buyon J, Kleinman C. Successful in utero therapy of fetal heart block. American Journal Of Obstetrics And Gynecology 1995, 173: 1384-1390. PMID: 7503173, DOI: 10.1016/0002-9378(95)90621-5.Peer-Reviewed Original ResearchConceptsComplete heart blockFetal heart blockHeart blockAntibody levelsCongenital complete heart blockHeart block patientsMaternal antibody levelsPositive antibody screenSimilar antibody levelsSecond-degree blockDegree of blockCardiac conduction systemFetal cardiac conduction systemConcurrent myocarditisGlucocorticoid therapyMaternal autoantibodiesBlock patientsMaternal antibodiesAntibody screenUtero therapyCord samplesCardiac contractilityRapid resolutionB antibodiesCardiac conduction