1995
Cellular mechanisms in the immune response to malaria in Plasmodium vinckei-infected mice
Perlmann H, Kumar S, Vinetz J, Kullberg M, Miller L, Perlmann P. Cellular mechanisms in the immune response to malaria in Plasmodium vinckei-infected mice. Infection And Immunity 1995, 63: 3987-3993. PMID: 7558309, PMCID: PMC173560, DOI: 10.1128/iai.63.10.3987-3993.1995.Peer-Reviewed Original ResearchConceptsImmune miceTh1 responseControl miceIL-4T cellsSpleen cellsIL-4-producing Th2 cellsBALB/c miceTumor necrosis factor alphaAbsence of elevationPlasmodium vinckei vinckeiImmunoglobulin E levelsInfection of miceGamma interferon productionNecrosis factor alphaChabaudi infectionAntigen exposureNonimmune miceImportant protective factorC miceSolid immunityTh2 cellsFactor alphaParasite antigensE levels
1990
Adoptive transfer of CD8+ T cells from immune animals does not transfer immunity to blood stage Plasmodium yoelii malaria.
Vinetz J, Kumar S, Good M, Fowlkes B, Berzofsky J, Miller L. Adoptive transfer of CD8+ T cells from immune animals does not transfer immunity to blood stage Plasmodium yoelii malaria. The Journal Of Immunology 1990, 144: 1069-74. PMID: 1967271, DOI: 10.4049/jimmunol.144.3.1069.Peer-Reviewed Original ResearchConceptsBlood-stage infectionT cellsSpleen cellsBALB/c miceBALB/c nu/nuMouse strainsClass I MHC AgMechanisms of CD8Vivo CD8 depletionAbsence of CD4Depletion of CD8P. yoelii infectionPopulation of CD4T-cell involvementAdoptive transfer experimentsPlasmodium yoelii 17XPlasmodium yoelii malariaUnfractionated spleen cellsBALB/cImmune CD4Immune CD8Vivo CD4CD8 depletionAdoptive transferImmune animals
1989
Interdependence of CD4+ T cells and malarial spleen in immunity to Plasmodium vinckei vinckei. Relevance to vaccine development.
Kumar S, Good M, Dontfraid F, Vinetz J, Miller L. Interdependence of CD4+ T cells and malarial spleen in immunity to Plasmodium vinckei vinckei. Relevance to vaccine development. The Journal Of Immunology 1989, 143: 2017-23. PMID: 2570802, DOI: 10.4049/jimmunol.143.6.2017.Peer-Reviewed Original ResearchConceptsBALB/c micePlasmodium vinckei vinckeiT cellsImmune miceC miceVivo depletionSpleen cellsNaive BALB/cAthymic nu/nu miceBALB/c nude miceC3H/HeN miceNu/nu miceImmune spleen cellsBALB/cLoss of immunityImmune CD4Malaria AgMalarial spleenVivo CD4Adoptive transferImmune spleenSplenectomized miceMalaria vaccineRodent malariaHeN mice