2024
Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments
Wallach J, Yoon S, Doernberg H, Glick L, Ciani O, Taylor R, Mooghali M, Ramachandran R, Ross J. Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments. JAMA 2024, 331: 1646-1654. PMID: 38648042, PMCID: PMC11036312, DOI: 10.1001/jama.2024.4175.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersChronic DiseaseClinical Trials as TopicHumansMeta-Analysis as TopicTreatment OutcomeConceptsMeta-analysesChronic diseasesFood and Drug AdministrationMeta-regression analysisMeta-analyses of observational studiesSurrogate markerClinical outcomesClinical trialsMeta-analysisEvidence of associationPublished meta-analysesStrength of associationMeta-analyses of clinical trialsChronic disease treatmentFood and Drug Administration tableResults of meta-regression analysisOutcome pairsFood and Drug Administration approvalMain OutcomesData extractionSystematic reviewStatistically significant resultsObservational studyPooled analysisDrug Administration
2022
Assessment of Hypothetical Out-of-Pocket Costs of Guideline-Recommended Medications for the Treatment of Older Adults With Multiple Chronic Conditions, 2009 and 2019
Zhou T, Liu P, Dhruva SS, Shah ND, Ramachandran R, Berg KM, Ross JS. Assessment of Hypothetical Out-of-Pocket Costs of Guideline-Recommended Medications for the Treatment of Older Adults With Multiple Chronic Conditions, 2009 and 2019. JAMA Internal Medicine 2022, 182: 185-195. PMID: 34982097, PMCID: PMC8728660, DOI: 10.1001/jamainternmed.2021.7457.Peer-Reviewed Original ResearchMeSH KeywordsAgedAtrial FibrillationChronic DiseaseCross-Sectional StudiesDiabetes Mellitus, Type 2Drug CostsHealth ExpendituresHeart FailureHumansHypercholesterolemiaHypertensionMedicare Part CMedicare Part DMultiple Chronic ConditionsOsteoarthritisOsteoporosisPrescription DrugsPulmonary Disease, Chronic ObstructiveRetrospective StudiesUnited StatesConceptsCommon chronic diseasesGuideline-recommended medicationsGuideline-recommended managementPrescription drug plansCross-sectional studyChronic conditionsChronic diseasesPocket costsOlder adultsOutpatient medicationsMedicare prescription drug plansInitial treatmentMedicare Advantage plansRetrospective cross-sectional studyMultiple chronic conditionsMedicare Part D plansPart D plansSubstantial financial burdenAtrial fibrillationMAIN OUTCOMEExclusion criteriaMedicare beneficiariesAnnual outHypothetical patientsMedications
2020
Medicare beneficiaries' out-of-pocket costs for commonly used generic drugs, 2009-2017.
Liu P, Dhruva SS, Shah ND, Ross JS. Medicare beneficiaries' out-of-pocket costs for commonly used generic drugs, 2009-2017. The American Journal Of Managed Care 2020, 26: 112-117. PMID: 32181626, DOI: 10.37765/ajmc.2020.42635.Peer-Reviewed Original ResearchConceptsPrescription drug plansPocket costsMedicare prescription drug plansGeneric drugsDrug price transparencyCash pricesPrice transparencyPocket expenditureDiscount programDrug plansDrug discount programsMedicare beneficiariesGeneric drug discount programsBeneficiariesCostGeneric drug prescriptionPricesDrug listGeneric medications
2019
On the Need for (Only) High-Quality Clinical Practice Guidelines
Incze M, Ross JS. On the Need for (Only) High-Quality Clinical Practice Guidelines. JAMA Internal Medicine 2019, 179: 561-561. PMID: 30776052, DOI: 10.1001/jamainternmed.2018.7471.Commentaries, Editorials and Letters
2018
Network Optimization And The Continuity Of Physicians In Medicaid Managed Care
Ndumele CD, Staiger B, Ross JS, Schlesinger MJ. Network Optimization And The Continuity Of Physicians In Medicaid Managed Care. Health Affairs 2018, 37: 929-935. PMID: 29863934, DOI: 10.1377/hlthaff.2017.1410.Peer-Reviewed Original ResearchMeSH KeywordsChronic DiseaseContinuity of Patient CareCost ControlDatabases, FactualDelivery of Health CareFemaleHealth ExpendituresHealth Maintenance OrganizationsHealth Services AccessibilityHumansMaleManaged Care ProgramsMedicaidPhysiciansPractice Patterns, Physicians'Retrospective StudiesUnited States
2017
Obstacles to the Adoption of Biosimilars for Chronic Diseases
Hakim A, Ross JS. Obstacles to the Adoption of Biosimilars for Chronic Diseases. JAMA 2017, 317: 2163-2164. PMID: 28459924, DOI: 10.1001/jama.2017.5202.Commentaries, Editorials and Letters
2016
Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over Time
Dharmarajan K, Qin L, Lin Z, Horwitz LI, Ross JS, Drye EE, Keshawarz A, Altaf F, Normand SL, Krumholz HM, Bernheim SM. Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over Time. Health Affairs 2016, 35: 1294-1302. PMID: 27385247, DOI: 10.1377/hlthaff.2015.1614.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCenters for Medicare and Medicaid Services, U.S.Chronic DiseaseDatabases, FactualDisease ProgressionFemaleGeriatric AssessmentHospital MortalityHumansIncidenceLength of StayMaleOutcome Assessment, Health CarePatient AdmissionPatient ReadmissionRetrospective StudiesRisk AssessmentSeverity of Illness IndexTime FactorsUnited States
2014
Decision-making and cancer screening: A qualitative study of older adults with multiple chronic conditions
Gross CP, Fried TR, Tinetti ME, Ross JS, Genao I, Hossain S, Wolf E, Lewis CL. Decision-making and cancer screening: A qualitative study of older adults with multiple chronic conditions. Journal Of Geriatric Oncology 2014, 6: 93-100. PMID: 25544380, DOI: 10.1016/j.jgo.2014.12.001.Peer-Reviewed Original ResearchConceptsCancer screening decisionsCancer screeningChronic conditionsCancer statusEducational promptsOlder personsMultiple chronic conditionsScreening decisionsDirect health benefitsMedical conditionsOverall healthOlder adultsThematic saturationHealth benefitsLife expectancyIndependent readersHealth scenarioMost respondentsScreeningAdultsAgeQualitative studySample sizeStatusMedications
2012
Association of Chronic Diseases and Impairments With Disability in Older Adults
Hung WW, Ross JS, Boockvar KS, Siu AL. Association of Chronic Diseases and Impairments With Disability in Older Adults. Medical Care 2012, 50: 501-507. PMID: 22584885, PMCID: PMC3353149, DOI: 10.1097/mlr.0b013e318245a0e0.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAgingCardiovascular DiseasesChronic DiseaseCognition DisordersCross-Sectional StudiesDiabetes MellitusDisabled PersonsFemaleHealth SurveysHearing LossHumansHypertensionMaleMobility LimitationResidence CharacteristicsRespiratory Tract DiseasesSelf CareSocioeconomic FactorsUnited StatesVision DisordersConceptsSelf-care disabilityChronic diseasesLung diseaseOlder adultsSelf-care ADLChronic lung diseaseCommunity-dwelling adultsCross-sectional analysisADL disabilityHeart failureHeart diseaseDaily livingHypertensionDiseaseDiabetesImpairmentDisabilityAdultsRetirement StudySpecific disabilitiesAssociationArthritisStrokeCancerADL
2011
Recent trends in chronic disease, impairment and disability among older adults in the United States
Hung WW, Ross JS, Boockvar KS, Siu AL. Recent trends in chronic disease, impairment and disability among older adults in the United States. BMC Geriatrics 2011, 11: 47. PMID: 21851629, PMCID: PMC3170191, DOI: 10.1186/1471-2318-11-47.Peer-Reviewed Original ResearchConceptsPrevalence of impairmentChronic diseasesOlder adultsDaily livingChronic lung diseaseMore chronic diseasesImpairment of cognitionPrevalence of disabilityOlder U.S. adultsProportion of respondentsIADL disabilityUrinary incontinenceLung diseaseHeart diseasePrevalence trendsInstrumental activitiesU.S. adultsDiseasePrevalenceImpairmentAdultsDisabilityMore diseasesRetirement StudyUnited States
2008
Electronic Health Record Components and the Quality of Care
Keyhani S, Hebert PL, Ross JS, Federman A, Zhu CW, Siu AL. Electronic Health Record Components and the Quality of Care. Medical Care 2008, 46: 1267-1272. PMID: 19300317, DOI: 10.1097/mlr.0b013e31817e18ae.Peer-Reviewed Original ResearchConceptsBlood pressure controlQuality of careAmbulatory Medical Care SurveyComplete electronic health recordElectronic health recordsElectronic reminder systemAppropriate therapyEHR componentsPressure controlCare SurveyChronic conditionsPhysician notesNational Hospital Ambulatory Medical Care SurveyNational Ambulatory Medical Care SurveyComputerized prescription order entryReminder systemException of angiotensinAngiotensin receptor blockersOrder entryPrimary care providersPrescription order entryImpact of EHRsCross-sectional analysisReceptor blockersNursing notes