2019
Use of Mechanical Cardiopulmonary Resuscitation Devices for Out-of-Hospital Cardiac Arrest, 2010-2016
Kahn PA, Dhruva SS, Rhee TG, Ross JS. Use of Mechanical Cardiopulmonary Resuscitation Devices for Out-of-Hospital Cardiac Arrest, 2010-2016. JAMA Network Open 2019, 2: e1913298. PMID: 31617923, PMCID: PMC6806423, DOI: 10.1001/jamanetworkopen.2019.13298.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overBlack or African AmericanCardiopulmonary ResuscitationCross-Sectional StudiesDatabases, FactualEmergency Medical ServicesFemaleHispanic or LatinoHumansIncomeMaleMiddle AgedNew EnglandOut-of-Hospital Cardiac ArrestRetrospective StudiesSex FactorsSuburban Health ServicesWhite PeopleYoung AdultConceptsHospital cardiac arrestMechanical cardiopulmonary resuscitationMechanical CPR deviceAdjusted odds ratioCardiac arrestCardiopulmonary resuscitationManual cardiopulmonary resuscitationCPR deviceOdds ratioNational Emergency Medical Services Information System dataUse of CPRRetrospective cross-sectional studyMechanical cardiopulmonary resuscitation devicesEMS professionalsRisk-standardized ratesPatient demographic characteristicsPrior clinical trialsCross-sectional studyEvidence of benefitCardiopulmonary resuscitation devicesEmergency medical services (EMS) professionalsNortheast census regionMultivariable analysisClinical trialsPrehospital settingU.S. prescribing trends of fentanyl, opioids, and other pain medications in outpatient and emergency department visits from 2006 to 2015
Vijay A, Rhee TG, Ross JS. U.S. prescribing trends of fentanyl, opioids, and other pain medications in outpatient and emergency department visits from 2006 to 2015. Preventive Medicine 2019, 123: 123-129. PMID: 30894321, PMCID: PMC6534435, DOI: 10.1016/j.ypmed.2019.03.022.Peer-Reviewed Original ResearchConceptsPain medication prescriptionsAmbulatory Medical Care SurveyOutpatient visitsED visitsMedication prescriptionsPain medicationCare SurveyNational Hospital Ambulatory Medical Care SurveyNational Ambulatory Medical Care SurveyOffice-based outpatient visitsNon-opioid alternativesCurrent opioid crisisEmergency department settingOpioid-related deathsPublic health interventionsRates of fentanylGeneral opioidOpioid prescribingFentanyl useED settingEmergency departmentOutpatient settingFentanyl productsDepartment settingOpioid products
2018
Trends in opioid use in commercially insured and Medicare Advantage populations in 2007-16: retrospective cohort study
Jeffery MM, Hooten WM, Henk HJ, Bellolio MF, Hess EP, Meara E, Ross JS, Shah ND. Trends in opioid use in commercially insured and Medicare Advantage populations in 2007-16: retrospective cohort study. The BMJ 2018, 362: k2833. PMID: 30068513, PMCID: PMC6066997, DOI: 10.1136/bmj.k2833.Peer-Reviewed Original ResearchConceptsMedicare Advantage beneficiariesAverage daily doseDisabled Medicare beneficiariesAged Medicare beneficiariesRetrospective cohort studyDaily doseOpioid useMedicare beneficiariesLong-term useCohort studyCommercial beneficiariesStudy periodUse prevalenceOpioid use prevalenceHigh rateMedicare Advantage populationTerm useAge 65 yearsOpioid use ratesAdministrative claims dataAverage daily dosesProportion of beneficiariesQuarterly prevalenceMorphine equivalentsOpioid prescriptions
2017
Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling.
Dharmarajan K, McNamara RL, Wang Y, Masoudi FA, Ross JS, Spatz EE, Desai NR, de Lemos JA, Fonarow GC, Heidenreich PA, Bhatt DL, Bernheim SM, Slattery LE, Khan YM, Curtis JP. Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling. Annals Of Internal Medicine 2017, 167: 555-564. PMID: 28973634, PMCID: PMC9359429, DOI: 10.7326/m16-2871.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesAcute myocardial infarctionOlder patientsYounger patientsMyocardial infarctionAge groupsHospital risk-standardized mortality ratesRetrospective cohort studyHospital mortality rankingsNational Quality ForumHospital mortalityMedian hospitalHospital outcomesCohort studyACTION RegistryAMI mortalityAmerican CollegeMedicare beneficiariesAMI hospitalizationPatientsMortality rateHospitalQuality ForumHospital ValueHospital profilingTrends in Omalizumab Utilization for Asthma: Evidence of Suboptimal Patient Selection
Jeffery MM, Shah ND, Karaca-Mandic P, Ross JS, Rank MA. Trends in Omalizumab Utilization for Asthma: Evidence of Suboptimal Patient Selection. The Journal Of Allergy And Clinical Immunology In Practice 2017, 6: 1568-1577.e4. PMID: 28958746, DOI: 10.1016/j.jaip.2017.07.034.Peer-Reviewed Original ResearchConceptsOmalizumab initiationAsthma controlICS-LABAPatient selectionLow adherenceBetter asthma controlCohort of nonusersSuboptimal patient selectionPoor asthma controlLow adherence ratesPatient-level characteristicsLarge US databaseMedicare Advantage beneficiariesAsthma biologicsExacerbation frequencyOmalizumab useIncident useComparison cohortICS/Medication adherenceAdherence ratesPrevalent usersAdministrative claimsAsthmaUtilization trends
2016
Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients
Parikh R, Ross JS, Sangaralingham LR, Adelman RA, Shah ND, Barkmeier AJ. Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients. Ophthalmology 2016, 124: 352-358. PMID: 27890437, DOI: 10.1016/j.ophtha.2016.10.036.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngiogenesis InhibitorsBevacizumabCohort StudiesDatabases, FactualDiabetic RetinopathyDrug UtilizationFemaleHumansInsurance, HealthIntravitreal InjectionsMacular DegenerationMaleMedicare Part CMiddle AgedOphthalmologyPrivate SectorRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinal Vein OcclusionRetrospective StudiesUnited StatesVascular Endothelial Growth Factor AYoung AdultConceptsAge-related macular degenerationDiabetic retinal diseaseAnti-VEGF injectionsIntravitreal anti-VEGF injectionsRetinal vein occlusionAdministrative claims dataRetinal diseasesOphthalmic diseasesVein occlusionClaims dataUse of bevacizumabCurrent Procedural Terminology codesPatients 18 yearsRetrospective cohort studyMedicare Advantage patientsOptumLabs Data WarehouseDrug Administration approvalProcedural Terminology codesGrowth factor useRanibizumab useBevacizumab useAvailable medicationsCohort studyMedication useCommon medicationsTrends in Drug Utilization, Glycemic Control, and Rates of Severe Hypoglycemia, 2006–2013
Lipska KJ, Yao X, Herrin J, McCoy RG, Ross JS, Steinman MA, Inzucchi SE, Gill TM, Krumholz HM, Shah ND. Trends in Drug Utilization, Glycemic Control, and Rates of Severe Hypoglycemia, 2006–2013. Diabetes Care 2016, 40: 468-475. PMID: 27659408, PMCID: PMC5360291, DOI: 10.2337/dc16-0985.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBlood GlucoseComorbidityDiabetes Mellitus, Type 2Dipeptidyl-Peptidase IV InhibitorsDrug UtilizationFemaleGlycated HemoglobinHumansHypoglycemiaHypoglycemic AgentsInsulinLogistic ModelsMaleMetforminMiddle AgedRetrospective StudiesSulfonylurea CompoundsThiazolidinedionesYoung AdultConceptsGlycemic controlSevere hypoglycemiaOlder patientsDipeptidyl peptidase-4 inhibitorsGlucose-lowering drugsGlucose-lowering medicationsProportion of patientsOverall glycemic controlPeptidase-4 inhibitorsMedicare Advantage patientsSex-standardized ratesType 2 diabetesOverall rateClass of agentsMore comorbiditiesChronic comorbiditiesYounger patientsAdvantage patientsDrug utilizationClaims dataPatientsHypoglycemiaHemoglobin AT2DMComorbiditiesA Nationwide Assessment of the Association of Smoking Bans and Cigarette Taxes With Hospitalizations for Acute Myocardial Infarction, Heart Failure, and Pneumonia
Ho V, Ross JS, Steiner CA, Mandawat A, Short M, Ku-Goto MH, Krumholz HM. A Nationwide Assessment of the Association of Smoking Bans and Cigarette Taxes With Hospitalizations for Acute Myocardial Infarction, Heart Failure, and Pneumonia. Medical Care Research And Review 2016, 74: 687-704. PMID: 27624634, PMCID: PMC5665160, DOI: 10.1177/1077558716668646.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationAcute myocardial infarctionHospitalization ratesSmoking bansFailure hospitalizationMyocardial infarctionCigarette taxesPneumonia hospitalization ratesPublic place smoking banComprehensive smoking banHigher cigarette taxesPersons age 60Pneumonia hospitalizationsHeart failureContemporaneous controlsProvider characteristicsHospitalizationAge 60State cigarette taxesHospitalization countsMultiple studiesLocal healthInfarctionNational studyAssociation
2015
HbA1c overtesting and overtreatment among US adults with controlled type 2 diabetes, 2001-13: observational population based study
McCoy RG, Van Houten HK, Ross JS, Montori VM, Shah ND. HbA1c overtesting and overtreatment among US adults with controlled type 2 diabetes, 2001-13: observational population based study. The BMJ 2015, 351: h6138. PMID: 26646052, PMCID: PMC4673101, DOI: 10.1136/bmj.h6138.Peer-Reviewed Original ResearchConceptsType 2 diabetesGlycemic controlControlled type 2 diabetesNational administrative claims databaseExcessive testingAdministrative claims databaseGood glycemic controlStable glycemic controlStudy patientsTreatment intensificationSevere hypoglycemiaTreatment regimenStudy cohortUS patientsClaims databasePotential overtreatmentUS cohortHypoglycemic drugsInsulin treatmentPatient burdenRetrospective analysisStudy populationUS adultsDiabetes managementObservational populationVariation in US Hospital Emergency Department Admission Rates by Clinical Condition
Venkatesh AK, Dai Y, Ross JS, Schuur JD, Capp R, Krumholz HM. Variation in US Hospital Emergency Department Admission Rates by Clinical Condition. Medical Care 2015, 53: 237-244. PMID: 25397965, PMCID: PMC4858175, DOI: 10.1097/mlr.0000000000000261.Peer-Reviewed Original ResearchConceptsEmergency Department Admission RatesED admission ratesAdmission ratesClinical conditionsMood disordersChronic obstructive pulmonary diseaseNational Emergency Department SampleAdult ED visitsNonspecific chest painObstructive pulmonary diseaseSoft tissue infectionsUrinary tract infectionEmergency Department SampleClinical Classification SoftwareCross-sectional analysisChest painED visitsTract infectionsPulmonary diseaseSpearman correlation coefficientTissue infectionsHospitalization ratesUS hospitalsCondition-specific variationsHospital correlation
2014
Pediatric screening urinalysis: a difference-in-differences analysis of how a 2007 change in guidelines impacted use
Filice CE, Green JC, Rosenthal MS, Ross JS. Pediatric screening urinalysis: a difference-in-differences analysis of how a 2007 change in guidelines impacted use. BMC Pediatrics 2014, 14: 260. PMID: 25303836, PMCID: PMC4287447, DOI: 10.1186/1471-2431-14-260.Peer-Reviewed Original ResearchConceptsChild visitsAdult visitsNational Ambulatory Medical Care SurveyMale childrenAmbulatory Medical Care SurveyPatient race/ethnicityFemale childrenCommunity health centersHigh-quality careRace/ethnicityPatient ageCare SurveyPatient genderAAP recommendationsPhysician specialtyHealth centersPediatrics recommendationsAmerican AcademyUrinalysisChildren 4VisitsYoung adultsMethodsUsing dataPrivate practiceChildrenHigh Incarceration Rates Among Black Men Enrolled In Clinical Studies May Compromise Ability To Identify Disparities
Wang EA, Aminawung JA, Wildeman C, Ross JS, Krumholz HM. High Incarceration Rates Among Black Men Enrolled In Clinical Studies May Compromise Ability To Identify Disparities. Health Affairs 2014, 33: 848-855. PMID: 24799583, PMCID: PMC4065793, DOI: 10.1377/hlthaff.2013.1325.Peer-Reviewed Original ResearchConceptsClinical studiesHealth outcomesBlack menProspective clinical studyObservational clinical researchBlood InstituteNational HeartClinical researchWhite womenRacial disparitiesWhite menMinimal riskMenBlack womenHigh rateJail inmatesMinority populationsWomenOutcomesEffects of incarcerationImpact of incarcerationHigh incarceration ratesIncarcerationLungFollow
2013
Hospital-based, acute care after ambulatory surgery center discharge
Fox JP, Vashi AA, Ross JS, Gross CP. Hospital-based, acute care after ambulatory surgery center discharge. Surgery 2013, 155: 743-753. PMID: 24787100, PMCID: PMC4114736, DOI: 10.1016/j.surg.2013.12.008.Peer-Reviewed Original ResearchMeSH KeywordsAdmitting Department, HospitalAdolescentAdultAgedAged, 80 and overAmbulatory Care FacilitiesAmbulatory Surgical ProceduresCaliforniaEmergency Service, HospitalFemaleFloridaHumansMaleMiddle AgedNebraskaOutcome Assessment, Health CarePatient DischargePatient ReadmissionPatient TransferTime FactorsYoung AdultConceptsAmbulatory surgery centersAcute care ratesHospital transfer ratesTime of dischargeHospital transferSurgery centersAcute careAdult patientsCare ratesAcute care needsRate of needAmbulatory care centersPrimary outcomeCare centerOperative procedureAmbulatory careHealthcare costsCare needsPatientsCenter dischargeUtilization ProjectFirst weekMeasures of qualityCareCenter levelHospital-Based, Acute Care Use Among Patients Within 30 Days of Discharge After Coronary Artery Bypass Surgery
Fox JP, Suter LG, Wang K, Wang Y, Krumholz HM, Ross JS. Hospital-Based, Acute Care Use Among Patients Within 30 Days of Discharge After Coronary Artery Bypass Surgery. The Annals Of Thoracic Surgery 2013, 96: 96-104. PMID: 23702228, PMCID: PMC3758868, DOI: 10.1016/j.athoracsur.2013.03.091.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCaliforniaCoronary Artery BypassCoronary Artery DiseaseEmergency Service, HospitalFemaleFollow-Up StudiesHumansIntensive Care UnitsLength of StayLinear ModelsMaleMiddle AgedMorbidityPatient DischargePatient ReadmissionPostoperative ComplicationsPostoperative PeriodPrognosisRecurrenceRetrospective StudiesRisk FactorsSurvival RateTime FactorsYoung AdultConceptsDays of dischargeAcute care needsCABG surgeryED visit ratesED visitsHospital readmissionReadmission ratesCare needsCoronary artery bypass graft surgeryVisit ratesArtery bypass graft surgeryCoronary artery bypass surgeryRisk-standardized readmission ratesAcute care ratesHospital 30 daysBypass graft surgeryAcute care useArtery bypass surgeryCongestive heart failureEmergency department visitsEmergency Department DatabasesChest discomfortGraft surgeryBypass surgeryHospital volume
2012
Impact of State Laws That Extend Eligibility for Parents’ Health Insurance Coverage to Young Adults
Blum AB, Kleinman LC, Starfield B, Ross JS. Impact of State Laws That Extend Eligibility for Parents’ Health Insurance Coverage to Young Adults. Pediatrics 2012, 129: 426-432. PMID: 22331339, PMCID: PMC3356137, DOI: 10.1542/peds.2011-1505.Peer-Reviewed Original ResearchConceptsHealth insurance coverageParents' insurancePhysical examYoung adultsBehavior Risk Factor Surveillance SystemRisk Factor Surveillance SystemRecent physical examInsurance coveragePhysicians/cliniciansForgone careAffordable Care ActClinician identificationHealth insurance companiesSelf-reported health insurance coverageAge 26Parents' policiesHealth insuranceCare ActCareDifferential improvementEligibilityAdultsSurveillance systemOutcomesPast year
2011
Do Imaging Studies Performed in Physician Offices Increase Downstream Utilization? An Empiric Analysis of Cardiac Stress Testing With Imaging
Chen J, Fazel R, Ross JS, McNamara RL, Einstein AJ, Al-Mallah M, Krumholz HM, Nallamothu BK. Do Imaging Studies Performed in Physician Offices Increase Downstream Utilization? An Empiric Analysis of Cardiac Stress Testing With Imaging. JACC Cardiovascular Imaging 2011, 4: 630-637. PMID: 21679898, PMCID: PMC3319749, DOI: 10.1016/j.jcmg.2011.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCardiac CatheterizationChi-Square DistributionEchocardiography, StressEmpirical ResearchFemaleHealthcare DisparitiesHumansInsurance, HealthLogistic ModelsMaleMiddle AgedMyocardial Perfusion ImagingMyocardial RevascularizationOffice VisitsOutpatient Clinics, HospitalPractice Patterns, Physicians'Predictive Value of TestsResidence CharacteristicsTime FactorsUnited StatesYoung AdultConceptsMyocardial perfusion imagingSubsequent myocardial perfusion imagingProportion of patientsStress echocardiographyCardiac catheterizationHospital outpatient settingPhysician's officeOutpatient settingStress testingSubsequent cardiac testingCardiac stress testingDownstream resource utilizationHospital outpatient facilitiesCardiac testingPrivate health insuranceDownstream testingOffice imagingPerfusion imagingCatheterizationImaging studiesOutpatient imagingPatientsHealth insuranceLower ratesHigh rate
2009
Economic Evaluation of a Comprehensive Teenage Pregnancy Prevention Program Pilot Program
Rosenthal MS, Ross JS, Bilodeau R, Richter RS, Palley JE, Bradley EH. Economic Evaluation of a Comprehensive Teenage Pregnancy Prevention Program Pilot Program. American Journal Of Preventive Medicine 2009, 37: s280-s287. PMID: 19896030, PMCID: PMC3020976, DOI: 10.1016/j.amepre.2009.08.014.Peer-Reviewed Original ResearchConceptsTeenage pregnancy prevention programsAge 30 yearsPregnancy prevention programsPrevention programsCommunity-based participatory research approachProgram operating costsTotal societal costsUnintended pregnancySocietal economic benefitsHigh-risk neighborhoodsCost effectivenessParticipatory research approachYoung adultsSocietal costsEconomic benefitsAdolescentsTeenage girlsEconomic evaluationComprehensive programPilot programYearsTotal social costSexual educationNeighborhood-based programsProgram participationExposure to Low-Dose Ionizing Radiation from Medical Imaging Procedures
Fazel R, Krumholz HM, Wang Y, Ross JS, Chen J, Ting HH, Shah ND, Nasir K, Einstein AJ, Nallamothu BK. Exposure to Low-Dose Ionizing Radiation from Medical Imaging Procedures. New England Journal Of Medicine 2009, 361: 849-857. PMID: 19710483, PMCID: PMC3707303, DOI: 10.1056/nejmoa0901249.Peer-Reviewed Original ResearchConceptsCumulative effective dosesCumulative effective doseEffective dosesEffective doseMean cumulative effective doseImaging proceduresLow-dose ionizing radiationPopulation-based ratesMedian effective doseOutpatient settingGeneral populationHigh dosesUtilization dataDosesEnrolleesStudy periodRadiation exposureNuclear imagingDoseAnnual effective dosesMedical imaging proceduresUnited StatesExposureHealth care marketYearsUse of Stroke Secondary Prevention Services
Ross JS, Halm EA, Bravata DM. Use of Stroke Secondary Prevention Services. Stroke 2009, 40: 1811-1819. PMID: 19265044, PMCID: PMC2768116, DOI: 10.1161/strokeaha.108.539619.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAspirinCross-Sectional StudiesData Interpretation, StatisticalDelivery of Health CareEthnicityFemaleGeographyHealth BehaviorHealth Care SurveysHealth StatusHealthcare DisparitiesHumansLife StyleMaleMiddle AgedPlatelet Aggregation InhibitorsRisk FactorsSex FactorsSocioeconomic FactorsStrokeUnited StatesYoung AdultConceptsSecondary prevention servicesOutpatient rehabilitationPrevention servicesRegular exerciseService useHealth care access characteristicsBehavior Risk Factor Surveillance SystemRisk Factor Surveillance SystemSmoking cessation counselingHistory of strokeMultivariable logistic regressionStroke Belt statesNon-Hispanic blacksOverall service useLow useState residenceSex-based differencesRace-based differencesPneumococcal vaccinationAntihypertensive medicationsCessation counselingStroke outcomeSelf-reported useAge 80Stroke Belt
2008
Racial and ethnic differences in personal cervical cancer screening amongst post-graduate physicians: Results from a cross-sectional survey
Ross JS, Nuñez-Smith M, Forsyth BA, Rosenbaum JR. Racial and ethnic differences in personal cervical cancer screening amongst post-graduate physicians: Results from a cross-sectional survey. BMC Public Health 2008, 8: 378. PMID: 18973674, PMCID: PMC2590615, DOI: 10.1186/1471-2458-8-378.Peer-Reviewed Original ResearchConceptsCervical cancer screeningCervical cancerCross-sectional surveyCancer screeningCervical cancer screening recommendationsEthnic differencesCancer screening recommendationsPerceptions of adherenceNon-significant tendencyScreening recommendationsUniversity HospitalEthnic disparitiesPhysiciansWomenCancerLess adherentAdherenceConvenience sampleHealth careCareScreeningBackgroundRacialAsiansRecommendationsResultsOverall