2024
Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments
Wallach J, Yoon S, Doernberg H, Glick L, Ciani O, Taylor R, Mooghali M, Ramachandran R, Ross J. Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments. JAMA 2024, 331: 1646-1654. PMID: 38648042, PMCID: PMC11036312, DOI: 10.1001/jama.2024.4175.Peer-Reviewed Original ResearchConceptsMeta-analysesChronic diseasesFood and Drug AdministrationMeta-regression analysisMeta-analyses of observational studiesSurrogate markerClinical outcomesClinical trialsMeta-analysisEvidence of associationPublished meta-analysesStrength of associationMeta-analyses of clinical trialsChronic disease treatmentFood and Drug Administration tableResults of meta-regression analysisOutcome pairsFood and Drug Administration approvalMain OutcomesData extractionSystematic reviewStatistically significant resultsObservational studyPooled analysisDrug Administration
2022
Assessment of Hypothetical Out-of-Pocket Costs of Guideline-Recommended Medications for the Treatment of Older Adults With Multiple Chronic Conditions, 2009 and 2019
Zhou T, Liu P, Dhruva SS, Shah ND, Ramachandran R, Berg KM, Ross JS. Assessment of Hypothetical Out-of-Pocket Costs of Guideline-Recommended Medications for the Treatment of Older Adults With Multiple Chronic Conditions, 2009 and 2019. JAMA Internal Medicine 2022, 182: 185-195. PMID: 34982097, PMCID: PMC8728660, DOI: 10.1001/jamainternmed.2021.7457.Peer-Reviewed Original ResearchMeSH KeywordsAgedAtrial FibrillationChronic DiseaseCross-Sectional StudiesDiabetes Mellitus, Type 2Drug CostsHealth ExpendituresHeart FailureHumansHypercholesterolemiaHypertensionMedicare Part CMedicare Part DMultiple Chronic ConditionsOsteoarthritisOsteoporosisPrescription DrugsPulmonary Disease, Chronic ObstructiveRetrospective StudiesUnited StatesConceptsCommon chronic diseasesGuideline-recommended medicationsGuideline-recommended managementPrescription drug plansCross-sectional studyChronic conditionsChronic diseasesPocket costsOlder adultsOutpatient medicationsMedicare prescription drug plansInitial treatmentMedicare Advantage plansRetrospective cross-sectional studyMultiple chronic conditionsMedicare Part D plansPart D plansSubstantial financial burdenAtrial fibrillationMAIN OUTCOMEExclusion criteriaMedicare beneficiariesAnnual outHypothetical patientsMedications
2012
Association of Chronic Diseases and Impairments With Disability in Older Adults
Hung WW, Ross JS, Boockvar KS, Siu AL. Association of Chronic Diseases and Impairments With Disability in Older Adults. Medical Care 2012, 50: 501-507. PMID: 22584885, PMCID: PMC3353149, DOI: 10.1097/mlr.0b013e318245a0e0.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAgingCardiovascular DiseasesChronic DiseaseCognition DisordersCross-Sectional StudiesDiabetes MellitusDisabled PersonsFemaleHealth SurveysHearing LossHumansHypertensionMaleMobility LimitationResidence CharacteristicsRespiratory Tract DiseasesSelf CareSocioeconomic FactorsUnited StatesVision DisordersConceptsSelf-care disabilityChronic diseasesLung diseaseOlder adultsSelf-care ADLChronic lung diseaseCommunity-dwelling adultsCross-sectional analysisADL disabilityHeart failureHeart diseaseDaily livingHypertensionDiseaseDiabetesImpairmentDisabilityAdultsRetirement StudySpecific disabilitiesAssociationArthritisStrokeCancerADL
2011
Recent trends in chronic disease, impairment and disability among older adults in the United States
Hung WW, Ross JS, Boockvar KS, Siu AL. Recent trends in chronic disease, impairment and disability among older adults in the United States. BMC Geriatrics 2011, 11: 47. PMID: 21851629, PMCID: PMC3170191, DOI: 10.1186/1471-2318-11-47.Peer-Reviewed Original ResearchConceptsPrevalence of impairmentChronic diseasesOlder adultsDaily livingChronic lung diseaseMore chronic diseasesImpairment of cognitionPrevalence of disabilityOlder U.S. adultsProportion of respondentsIADL disabilityUrinary incontinenceLung diseaseHeart diseasePrevalence trendsInstrumental activitiesU.S. adultsDiseasePrevalenceImpairmentAdultsDisabilityMore diseasesRetirement StudyUnited States