1990
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury
Bracken M, Shepard M, Collins W, Holford T, Young W, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury. New England Journal Of Medicine 1990, 322: 1405-1411. PMID: 2278545, DOI: 10.1056/nejm199005173222001.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryNeurologic recoverySafety of methylprednisoloneSystematic neurological examinationPlacebo-controlled trialHours of injuryMajor morbidityNeurologic outcomeControlled TrialsNeurological examinationIncomplete lesionsMotor functionMethylprednisoloneNaloxonePatientsBody weightSensory functionInjuryPlaceboInfusionBolusEffective remainsTreatmentDose
1988
Late neurological changes following traumatic spinal cord injury.
Piepmeier J, Jenkins N. Late neurological changes following traumatic spinal cord injury. Journal Of Neurosurgery 1988, 69: 399-402. PMID: 3404238, DOI: 10.3171/jns.1988.69.3.0399.Peer-Reviewed Original ResearchConceptsSpinal cord injuryTraumatic spinal cord injuryCord injuryNeurological functionPatient's spinal cord injuryFunctional neurological statusFrankel scaleNeurological statusNeurological examinationSpinal traumaYears postinjuryNeurological changesPatient statusInjuryMajority of improvementsPatientsExaminationSignificant changesStatusYearsPostinjuryHospitalTrauma