2017
CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation
Kuwahara G, Hashimoto T, Tsuneki M, Yamamoto K, Assi R, Foster TR, Hanisch JJ, Bai H, Hu H, Protack CD, Hall MR, Schardt JS, Jay SM, Madri JA, Kodama S, Dardik A. CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation. Arteriosclerosis Thrombosis And Vascular Biology 2017, 37: 1147-1156. PMID: 28450292, PMCID: PMC5467640, DOI: 10.1161/atvbaha.117.309385.Peer-Reviewed Original ResearchConceptsExtracellular matrix depositionKnockout miceExtracellular matrix componentsExtracellular matrix productionMatrix depositionAdhesion molecule-1 expressionM2 macrophagesProtein 1Matrix productionCell adhesion molecule-1 expressionMolecule-1 expressionProtein expressionMatrix componentsCD44 knockout miceProtein-1 expressionMajor receptorCD44 activityMaturationVascular cell adhesion molecule-1 expressionAdhesion moleculesExpressionCD44 mRNAChemoattractant protein-1 expressionWild-type C57BL/6JArteriovenous fistula
1991
Selective Activation of Th1‐ and Th2‐like Cells in vivo– Response to Human Collagen IV
Pfeiffer C, Murray J, Madri J, Bottomly K. Selective Activation of Th1‐ and Th2‐like Cells in vivo– Response to Human Collagen IV. Immunological Reviews 1991, 123: 65-84. PMID: 1684784, DOI: 10.1111/j.1600-065x.1991.tb00606.x.Peer-Reviewed Original ResearchConceptsT cell proliferative responsesTh2 responsesProliferative responseTh2 cellsT cellsT cell IL-4Collagen IVClass of immunityMHC class II moleculesT cell responsesActivation of Th1IFN-gamma releaseClass II MHC moleculesIL-5 releaseTypes of CD4Th2-like cellsClass II genotypesClass II moleculesMHC class II genotypeII MHC moleculesType of responseT cell ligandsMHC genotypeTh1 responseGamma release