1992
Major histocompatibility complex (MHC) control of CD4 T cell subset activation. II. A single peptide induces either humoral or cell‐mediated responses in mice of distinct MHC genotype
Murray J, Pfeiffer C, Madri J, Bottomly K. Major histocompatibility complex (MHC) control of CD4 T cell subset activation. II. A single peptide induces either humoral or cell‐mediated responses in mice of distinct MHC genotype. European Journal Of Immunology 1992, 22: 559-565. PMID: 1347015, DOI: 10.1002/eji.1830220239.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibody FormationAntigen-Presenting CellsCD4-Positive T-LymphocytesCollagenGenes, MHC Class IIHaptensHumansImmunity, CellularImmunologic MemoryLymph NodesLymphocyte ActivationLymphocyte CooperationMajor Histocompatibility ComplexMiceMolecular Sequence DataPeptidesT-Lymphocytes, Helper-Inducer
1989
MHC control of CD4+ T cell subset activation.
Murray J, Madri J, Tite J, Carding S, Bottomly K. MHC control of CD4+ T cell subset activation. Journal Of Experimental Medicine 1989, 170: 2135-2140. PMID: 2573684, PMCID: PMC2189542, DOI: 10.1084/jem.170.6.2135.Peer-Reviewed Original ResearchConceptsT cellsIL-2IL-4-producing CD4T cell subset activationIL-4-producing cellsI-Ab miceMHC class II haplotypesCytokine-producing CD4T-cell phenotypeTypes of CD4Secondary IgG responsesClass II MHCSelective activationClass II haplotypesMHC controlSuch selective activationCytokine phenotypeIgG responsesSubset activationII MHCImmune responseProliferative responseCD4Vivo responseMice
1987
Inverse Ir gene control of the antibody and T cell proliferative responses to human basement membrane collagen.
Tite J, Foellmer H, Madri J, Janeway C. Inverse Ir gene control of the antibody and T cell proliferative responses to human basement membrane collagen. The Journal Of Immunology 1987, 139: 2892-8. PMID: 3117879, DOI: 10.4049/jimmunol.139.9.2892.Peer-Reviewed Original ResearchConceptsT cell proliferative responsesCell proliferative responsesAntibody responseIr gene controlProliferative responseT cellsHigher antibody responseClass II MHCMHC congenic miceMajor histocompatibility complexImmunologic responsivenessResponder parentF1 miceII MHCDifferent MHC genotypesImmune responseType IV collagenCongenic miceMiceHistocompatibility complexIV collagenDifferential activationAntigenBasement membrane collagenMHC genotype
1981
The immune response to human type III and type V (AB2) collagen: antigenic determinants and genetic control in mice
Kemp J, Madri J. The immune response to human type III and type V (AB2) collagen: antigenic determinants and genetic control in mice. European Journal Of Immunology 1981, 11: 90-94. PMID: 6163643, DOI: 10.1002/eji.1830110205.Peer-Reviewed Original ResearchConceptsAntibody responseSpecific IgG antibody responseAntigenic determinantsIgG antibody responseHigher antibody responseT cell recognitionType IIIType IHuman type IIIHigh-affinity monoclonal antibodiesAntigen presentationImmune responseBovine collagen type IMonoclonal antibodiesCollagen type IIr genesType V collagenCell recognitionHuman collagenFurther studiesConnective tissue biologyTissue biologyMicePresent studyCollagen