2001
PECAM‐1 shedding during apoptosis generates a membrane‐anchored truncated molecule with unique signaling characteristics
ILAN N, MOHSENIN A, CHEUNG L, MADRI J. PECAM‐1 shedding during apoptosis generates a membrane‐anchored truncated molecule with unique signaling characteristics. The FASEB Journal 2001, 15: 362-372. PMID: 11156952, DOI: 10.1096/fj.00-0372com.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid Chloromethyl KetonesAnimalsAntigens, CDApoptosisBlood PlateletsCaspasesCattleCell DivisionCell LineCell MembraneCells, CulturedColonic NeoplasmsCulture MediaDipeptidesEndothelium, VascularEnzyme InhibitorsHumansPlatelet Endothelial Cell Adhesion Molecule-1Sequence DeletionSignal TransductionTransfectionTumor Cells, CulturedUmbilical VeinsConceptsFull-length PECAM-1Signal transduction cascadeSignal transduction eventsCaspase-8 cleavageCell proliferationPECAM-1SW480 colon carcinoma cellsCaspase substratesSHP-2Transduction cascadeTransduction eventsGrowth factor receptorCell adhesion moleculeGene constructsCell surface moleculesColon carcinoma cellsSoluble proteinStable expressionCell deathCulture mediumMatrix metalloproteinaseCell surfaceJNK phosphorylationUnique functionFactor receptor
1994
Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines.
Turowski G, Rashid Z, Hong F, Madri J, Basson M. Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines. Cancer Research 1994, 54: 5974-80. PMID: 7954430.Peer-Reviewed Original ResearchMeSH KeywordsAlkaline PhosphataseBeta-GalactosidaseCathepsin CCell AdhesionCell DifferentiationCell DivisionColonic NeoplasmsDipeptidyl-Peptidases and Tripeptidyl-PeptidasesDose-Response Relationship, DrugExtracellular Matrix ProteinsGlutamineHumansIntegrinsLactaseOligo-1,6-GlucosidasePhenotypeTumor Cells, CulturedConceptsMatrix proteinsHuman colon carcinoma cell lineColon carcinoma cell lineCell linesCarcinoma cell linesSurface expressionDigestive enzyme expressionGlutamine-free mediumCell-matrix interactionsColon cancer cell linesHuman colon cancer cell linesCaco-2 proliferationSerial cell countsIntegrin surface expressionSW620 cellsCancer cell linesDigestive enzymesProteinEnzyme expressionGlutamineSynthetic substratesAdherent cellsCathepsin CExpressionIntegrin expression
1992
Cancer cell binding to E-selectin transfected human endothelia
Merwin J, Madri J, Lynch M. Cancer cell binding to E-selectin transfected human endothelia. Biochemical And Biophysical Research Communications 1992, 189: 315-323. PMID: 1280420, DOI: 10.1016/0006-291x(92)91560-d.Peer-Reviewed Original Research