2017
CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation
Kuwahara G, Hashimoto T, Tsuneki M, Yamamoto K, Assi R, Foster TR, Hanisch JJ, Bai H, Hu H, Protack CD, Hall MR, Schardt JS, Jay SM, Madri JA, Kodama S, Dardik A. CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation. Arteriosclerosis Thrombosis And Vascular Biology 2017, 37: 1147-1156. PMID: 28450292, PMCID: PMC5467640, DOI: 10.1161/atvbaha.117.309385.Peer-Reviewed Original ResearchConceptsExtracellular matrix depositionKnockout miceExtracellular matrix componentsExtracellular matrix productionMatrix depositionAdhesion molecule-1 expressionM2 macrophagesProtein 1Matrix productionCell adhesion molecule-1 expressionMolecule-1 expressionProtein expressionMatrix componentsCD44 knockout miceProtein-1 expressionMajor receptorCD44 activityMaturationVascular cell adhesion molecule-1 expressionAdhesion moleculesExpressionCD44 mRNAChemoattractant protein-1 expressionWild-type C57BL/6JArteriovenous fistula
2003
Transcriptional Up-regulation of Endothelial Cell Matrix Metalloproteinase-2 in Response to Extracellular Cues Involves GATA-2*
Han X, Boyd PJ, Colgan S, Madri JA, Haas TL. Transcriptional Up-regulation of Endothelial Cell Matrix Metalloproteinase-2 in Response to Extracellular Cues Involves GATA-2*. Journal Of Biological Chemistry 2003, 278: 47785-47791. PMID: 14512418, DOI: 10.1074/jbc.m309482200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBlotting, NorthernBlotting, WesternCell NucleusCells, CulturedCollagenCOS CellsDNA-Binding ProteinsEndothelial CellsExtracellular MatrixGATA2 Transcription FactorGelatinGenes, ReporterLuciferasesMatrix Metalloproteinase 2MicrocirculationMolecular Sequence DataNeovascularization, PhysiologicPhenotypePromoter Regions, GeneticProtein BindingRatsTranscription FactorsTranscription, GeneticTranscriptional ActivationTransfectionUp-Regulation
1996
Regulation of human colonic cell line proliferation and phenotype by sodium butyrate
Basson M, Turowski G, Rashid Z, Hong F, Madri J. Regulation of human colonic cell line proliferation and phenotype by sodium butyrate. Digestive Diseases And Sciences 1996, 41: 1986-1993. PMID: 8888712, DOI: 10.1007/bf02093601.Peer-Reviewed Original ResearchConceptsBrush border enzyme activitiesSerial cell countsCell line proliferationHuman colonic cellsColonic butyrateApparent protective actionColon carcinogenesisMalignant behaviorCell countButyrate effectMucosal differentiationColonic cellsProtective actionSodium butyrateCaco-2Surface expressionCollagen ICollagen IVDietary fiberProliferationRelevant concentrationsCarcinogenesisCultured cellsMotilityMatrix proteins
1994
Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines.
Turowski G, Rashid Z, Hong F, Madri J, Basson M. Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines. Cancer Research 1994, 54: 5974-80. PMID: 7954430.Peer-Reviewed Original ResearchMeSH KeywordsAlkaline PhosphataseBeta-GalactosidaseCathepsin CCell AdhesionCell DifferentiationCell DivisionColonic NeoplasmsDipeptidyl-Peptidases and Tripeptidyl-PeptidasesDose-Response Relationship, DrugExtracellular Matrix ProteinsGlutamineHumansIntegrinsLactaseOligo-1,6-GlucosidasePhenotypeTumor Cells, CulturedConceptsMatrix proteinsHuman colon carcinoma cell lineColon carcinoma cell lineCell linesCarcinoma cell linesSurface expressionDigestive enzyme expressionGlutamine-free mediumCell-matrix interactionsColon cancer cell linesHuman colon cancer cell linesCaco-2 proliferationSerial cell countsIntegrin surface expressionSW620 cellsCancer cell linesDigestive enzymesProteinEnzyme expressionGlutamineSynthetic substratesAdherent cellsCathepsin CExpressionIntegrin expression
1993
Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells
Marx M, Daniel T, Kashgarian M, Madri J. Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells. Kidney International 1993, 43: 1027-1041. PMID: 8510381, DOI: 10.1038/ki.1993.145.Peer-Reviewed Original ResearchConceptsPDGF receptor subunitsMesangial cell phenotypeCell surfaceExtracellular matrixCell phenotypeExtracellular matrix environmentSpatial organizationPDGF responsivenessPDGF receptor alphaTwo-dimensional cultureMulticellular structuresThree-dimensional cultureMetabolic labelingDifferential expressionQuiescent cellsRat mesangial cell growthCell growthPDGF isoforms AASubunitsMatrix environmentCell proliferationPDGF isoformsReceptor subunitsUltrastructural analysisSurface expression
1992
Matrix composition, organization and soluble factors: Modulators of microvascular cell differentiation in vitro
Madri J, Marx M. Matrix composition, organization and soluble factors: Modulators of microvascular cell differentiation in vitro. Kidney International 1992, 41: 560-565. PMID: 1573829, DOI: 10.1038/ki.1992.82.Peer-Reviewed Original ResearchConceptsCell typesStructure/functionMajor cell typesExtracellular matrix componentsVascular cell behaviorVascular smooth muscle cellsEndothelial cellsCell differentiationSoluble factorsCell behaviorExtracellular matrixNeighboring cellsMetabolic functionsDirect interactionSmooth muscle cellsMatrix componentsCell populationsMorphological organizationMuscle cellsMicrovascular endothelial cellsCulture modelCellsMesangial cell populationOrgan culture modelCell isolation
1988
Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.
Madri J, Pratt B, Tucker A. Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix. Journal Of Cell Biology 1988, 106: 1375-1384. PMID: 3283153, PMCID: PMC2115017, DOI: 10.1083/jcb.106.4.1375.Peer-Reviewed Original Research
1987
Retinol and extracellular collagen matrices modulate hepatic Ito cell collagen phenotype and cellular retinol binding protein levels.
Davis B, Pratt B, Madri J. Retinol and extracellular collagen matrices modulate hepatic Ito cell collagen phenotype and cellular retinol binding protein levels. Journal Of Biological Chemistry 1987, 262: 10280-10286. PMID: 3301832, DOI: 10.1016/s0021-9258(18)61109-3.Peer-Reviewed Original Research
1983
Capillary endothelial cell cultures: phenotypic modulation by matrix components.
Madri J, Williams S. Capillary endothelial cell cultures: phenotypic modulation by matrix components. Journal Of Cell Biology 1983, 97: 153-165. PMID: 6190818, PMCID: PMC2112496, DOI: 10.1083/jcb.97.1.153.Peer-Reviewed Original Research