2001
PECAM-1 Is a Modulator of STAT Family Member Phosphorylation and Localization: Lessons from a Transgenic Mouse
Ilan N, Cheung L, Miller S, Mohsenin A, Tucker A, Madri J. PECAM-1 Is a Modulator of STAT Family Member Phosphorylation and Localization: Lessons from a Transgenic Mouse. Developmental Biology 2001, 232: 219-232. PMID: 11254359, DOI: 10.1006/dbio.2001.0186.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DivisionCell NucleusCells, CulturedDNA-Binding ProteinsEndothelium, VascularFemaleHumansMammary Glands, AnimalMiceMice, TransgenicMilk ProteinsMorphogenesisPhosphorylationPlatelet Endothelial Cell Adhesion Molecule-1Pulmonary AlveoliSTAT5 Transcription FactorTrans-ActivatorsTumor Suppressor ProteinsConceptsImmunoreceptor tyrosine activation motifMilk protein gene expressionPhosphorylation levelsSignal transduction pathwaysProtein gene expressionTyrosine activation motifTyrosine phosphorylation levelsPECAM-1Cell cycle progressionMammary gland developmentInduction of p21Cytoplasmic tailBranching morphogenesisTransduction pathwaysTransgenic miceActivation motifCell adhesion moleculeDuctal epithelial cell proliferationGene expressionCycle progressionGland developmentEpithelial cell proliferationDuctal branching morphogenesisCell proliferationVascular cells
1992
Interactions of Matrix Components and Soluble Factors in Vascular Responses to Injury
Madri J, Merwin J, Bell L, Basson C, Kocher O, Perlmutter R, Prinz C. Interactions of Matrix Components and Soluble Factors in Vascular Responses to Injury. 1992, 11-30. DOI: 10.1007/978-1-4899-0721-9_2.Peer-Reviewed Original ResearchSmooth muscle cellsMuscle cellsEndothelial cellsMatrix componentsSheet migrationWall integrityLarge vessel endothelial cellsExtracellular matrixVessel wall integrityVascular cellsVessel endothelial cellsActive endothelial cellsMetabolic activityMicrovascular endothelial cellsInterstitial stromaMedial smooth muscle cellsCellsDenudation injuryClose association
1991
Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: Models of de‐endothelialization and repair
Madri J, Marx M, Merwin J, Basson C, Prinz C, Bell L. Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: Models of de‐endothelialization and repair. Journal Of Cellular Biochemistry 1991, 45: 123-130. PMID: 1711525, DOI: 10.1002/jcb.240450202.Peer-Reviewed Original ResearchConceptsSoluble factorsEndothelial cellsVascular smooth muscle cellsCell populationsSite of injuryMicrovascular endothelial cellsSmooth muscle cellsVessel endothelial cellsEndothelial vascular cellsLarge vessel endothelial cellsVascular cell populationsCell typesIntimal thickeningDenudation injuryVascular cell typesArterial mediaSubsequent lumen formationDifferent cell populationsInjuryCell responsesMuscle cellsVascular cellsExtracellular matrixSoft tissueVascular cell behaviorVascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro.
Merwin J, Newman W, Beall L, Tucker A, Madri J. Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro. American Journal Of Pathology 1991, 138: 37-51. PMID: 1846264, PMCID: PMC1886039.Peer-Reviewed Original ResearchConceptsBovine aortic endothelial cellsBovine aortic smooth muscle cellsGrowth factorGrowth factor beta 1Aortic smooth muscle cellsTGF-beta concentrationsSmooth muscle cellsProliferation of BAECsTGF-beta receptorsBovine aortic endothelial cell migrationType IAortic endothelial cellsTGF beta sCell typesMicrovascular endotheliumVascular cell typesReceptor assayMuscle cellsVascular cellsEndothelial cellsBeta 1Endothelial cell migrationBeta 2Angiogenic assaysBASMCs
1989
The Interactions of Vascular Cells with Solid Phase (Matrix) and Soluble Factors
Madri J, Kocher O, Merwin J, Bell L, Yannariello-Brown J. The Interactions of Vascular Cells with Solid Phase (Matrix) and Soluble Factors. Journal Of Cardiovascular Pharmacology 1989, 14: s70-s75. DOI: 10.1097/00005344-198900146-00015.Peer-Reviewed Original ResearchVascular bedSoluble factorsVascular cellsEndothelial cellsVascular smooth muscle cellsCell populationsSite of injuryMicrovascular endothelial cellsSmooth muscle cellsVessel endothelial cellsLarge vessel endothelial cellsVascular cell populationsVascular injuryIntimal thickeningInjury variesPlatelet factorInjuryMuscle cellsSoft tissueTube formationVessel wallHeterogeneous cell populationsCell typesCellsRepair processThe Interactions of Vascular Cells with Solid Phase (Matrix) and Soluble Factors
Madri J, Kocher O, Merwin J, Bell L, Yannariello-Brown J. The Interactions of Vascular Cells with Solid Phase (Matrix) and Soluble Factors. Journal Of Cardiovascular Pharmacology 1989, 14: s70-s75. PMID: 2478828, DOI: 10.1097/00005344-198906146-00015.Peer-Reviewed Original ResearchConceptsVascular bedSoluble factorsVascular cellsEndothelial cellsVascular smooth muscle cellsCell populationsSite of injuryMicrovascular endothelial cellsSmooth muscle cellsVessel endothelial cellsLarge vessel endothelial cellsVascular cell populationsVascular injuryIntimal thickeningInjury variesPlatelet factorInjuryMuscle cellsSoft tissueTube formationVessel wallHeterogeneous cell populationsCell typesCellsRepair process