1984
Antibody Response in Lyme Disease: Evaluation of Diagnostic Tests
Craft J, Grodzicki R, Steere A. Antibody Response in Lyme Disease: Evaluation of Diagnostic Tests. The Journal Of Infectious Diseases 1984, 149: 789-795. PMID: 6373966, DOI: 10.1093/infdis/149.5.789.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayAntibody responseLyme diseaseIgM antibodiesAntibody titersSpecific IgM antibody titersDiagnostic testsSpecific IgG antibody titersIgG antibody titersIgM antibody titersSerial serum samplesSpecific IgM antibodiesMonths of remissionCross-reactive antibodiesIxodes dammini spirocheteBetter diagnostic testsTiters of seraEarly diseaseControl subjectsAdsorption of serumPatientsSuch titersHigh titersDiseaseSerum samples
1983
The Spirochetal Etiology of Lyme Disease
Steere A, Grodzicki R, Kornblatt A, Craft J, Barbour A, Burgdorfer W, Schmid G, Johnson E, Malawista S. The Spirochetal Etiology of Lyme Disease. New England Journal Of Medicine 1983, 308: 733-740. PMID: 6828118, DOI: 10.1056/nejm198303313081301.Peer-Reviewed Original ResearchConceptsLyme diseaseAntibody titersIgM titersSpecific IgM antibody titersSpecific IgG antibody titersElevated IgM titersI. dammini spirocheteIgG antibody titersIgM antibody titersTiters of IgGOnset of diseaseInfectious mononucleosisControl patientsImmunologic featuresIgG titersEarly diseaseControl subjectsSpirochetal etiologySkin lesionsCerebrospinal fluidPatientsLate manifestationSixth weekDiseaseTiters