2008
The Role of ICOS in Peripheral Inflammation in Lupus
Eardley L, Odegard J, Craft J. The Role of ICOS in Peripheral Inflammation in Lupus. The FASEB Journal 2008, 22: 668.18-668.18. DOI: 10.1096/fasebj.22.1_supplement.668.18.Peer-Reviewed Original ResearchCostimulatory molecule ICOST cellsPeripheral inflammationDendritic cellsChemokine receptorsMRL/Faslpr miceExpression of CCR6Role of ICOSChemokine receptor expressionMajority of CD4Role of CD4Lupus-prone miceSevere renal diseaseFaslpr miceIndependent cytokinesLupus nephritisEffector cytokinesIL-10Lupus miceRenal diseaseCellular infiltrateChemokine productionSuch inflammationIL-5Certain chemokines
1997
alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity.
Peng SL, McNiff JM, Madaio MP, Ma J, Owen MJ, Flavell RA, Hayday AC, Craft J. alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. The Journal Of Immunology 1997, 158: 2464-70. PMID: 9036998, DOI: 10.4049/jimmunol.158.5.2464.Peer-Reviewed Original ResearchConceptsAlpha beta T cellsBeta T cellsGamma delta T cellsAutoimmune skin diseaseDelta T cellsT cellsRenal diseaseSystemic autoimmunitySkin diseasesAutoantibody productionMurine lupusCutaneous diseaseT cell-dependent mechanismAlpha betaHigh-titer autoantibodiesLupus-prone miceSevere renal diseaseCell-dependent mechanismT cell regulationCutaneous lesionsCD40 ligandAutoantibodiesAutoimmunityLow titersLpr animals
1996
Propagation and regulation of systemic autoimmunity by gammadelta T cells.
Peng SL, Madaio MP, Hayday AC, Craft J. Propagation and regulation of systemic autoimmunity by gammadelta T cells. The Journal Of Immunology 1996, 157: 5689-98. PMID: 8955223, DOI: 10.4049/jimmunol.157.12.5689.Peer-Reviewed Original ResearchConceptsGammadelta T cellsAlphabeta T cellsT cellsRenal diseaseMurine lupusSystemic autoimmunityImmune complex renal diseaseT cell-intact miceRoles of alphabetaT-cell-deficient animalsLupus-prone miceSevere renal diseaseComplex renal diseaseLupus syndromeAutoantibody productionConventional CD4Polyclonal expansionPathogenic roleMiceHypergammaglobulinemiaDisease phenotypeAutoimmunityLupusDiseaseCells