Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles.
Ohosone Y, Mimori T, Griffith A, Akizuki M, Homma M, Craft J, Hardin JA. Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 4249-4253. PMID: 2524838, PMCID: PMC287428, DOI: 10.1073/pnas.86.11.4249.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusSm snRNPsHuman fibroblast cDNA libraryAmino acidsAlternative splicing mechanismLupus erythematosusFibroblast cDNA librarySmall nuclear ribonucleoproteinOpen reading frameAmino acid sequenceSplicing mechanismMolecular cloningCDNA libraryNuclear ribonucleoproteinReading frameAnti-Sm antibodiesB polypeptidesAcid sequenceCOOH terminusNH2 terminusCDNAComplete homologySnRNPsPolypeptide NPolypeptide