2003
Role of the H‐2 haplotype in Fas‐intact lupus‐prone MRL mice: association with autoantibodies but not renal disease
Kong PL, Zhu T, Madaio MP, Craft J. Role of the H‐2 haplotype in Fas‐intact lupus‐prone MRL mice: association with autoantibodies but not renal disease. Arthritis & Rheumatism 2003, 48: 2992-2995. PMID: 14558109, DOI: 10.1002/art.11308.Peer-Reviewed Original ResearchCD4+ T Cells from Lupus-Prone Mice Avoid Antigen-Specific Tolerance Induction In Vivo
Bouzahzah F, Jung S, Craft J. CD4+ T Cells from Lupus-Prone Mice Avoid Antigen-Specific Tolerance Induction In Vivo. The Journal Of Immunology 2003, 170: 741-748. PMID: 12517936, DOI: 10.4049/jimmunol.170.2.741.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsAutoantigensCD4-Positive T-LymphocytesCell DivisionCell SeparationCells, CulturedClonal AnergyEpitopes, T-LymphocyteGenetic Predisposition to DiseaseLupus NephritisLymphocyte CountMiceMice, Inbred C57BLMice, Inbred CBAMice, Inbred MRL lprMice, TransgenicReceptors, Antigen, T-Cell, alpha-betaConceptsPigeon cytochrome cT cellsIL-2Self-AgCostimulatory signalsAntigen-specific tolerance inductionMRL xTCR transgenic T cellsLupus-prone MRL miceMRL T cellsNormal tolerance mechanismsUbiquitous self-AgsVivo Ag stimulationLupus-prone miceSuch T cellsPeripheral tolerance mechanismsCBA/CaJControl T cellsEx vivo recall assaysActivated T cellsT cell activationInappropriate T-cell activationThymic toleranceMRL/Recall assays
1996
T cells in murine lupus: propagation and regulation of disease
Peng S, Craft J. T cells in murine lupus: propagation and regulation of disease. Molecular Biology Reports 1996, 23: 247-251. PMID: 9112236, DOI: 10.1007/bf00351176.Peer-Reviewed Original ResearchConceptsΓδ T cellsΑβ T cellsT cellsLupus syndromeRenal diseaseMurine lupusCell helpMRL/lpr B cellsMRL/Mp-lpr/lpr miceImmune complex renal diseaseT cell-dependent mechanismLupus-prone MRL miceClass-switched autoantibodiesClass-switched immunoglobulinsSpecific autoimmune responseT-cell-deficient animalsCell-dependent mechanismB cell helpLpr B cellsT cell helpComplex renal diseaseB cell autoimmunityWild-type animalsPathogenesis of diseaseCause tissue injuryMurine lupus in the absence of alpha beta T cells.
Peng SL, Madaio MP, Hughes DP, Crispe IN, Owen MJ, Wen L, Hayday AC, Craft J. Murine lupus in the absence of alpha beta T cells. The Journal Of Immunology 1996, 156: 4041-9. PMID: 8621947, DOI: 10.4049/jimmunol.156.10.4041.Peer-Reviewed Original ResearchConceptsAlpha beta T cellsT cell-dependent mechanismBeta T cellsCell-dependent mechanismT cellsMurine lupusHuman systemic lupus erythematosusLupus-prone MRL miceSystemic lupus erythematosusSystemic autoimmune diseaseLupus erythematosusAutoimmune diseasesImmune depositsMRL miceAlpha betaLupusDiseaseMiceCellsErythematosusHypergammaglobulinemiaAutoantibodiesCD4AutoimmunityKidney