B cells process and present lupus autoantigens that initiate autoimmune T cell responses.
Mamula MJ, Fatenejad S, Craft J. B cells process and present lupus autoantigens that initiate autoimmune T cell responses. The Journal Of Immunology 1994, 152: 1453-61. PMID: 8301145, DOI: 10.4049/jimmunol.152.3.1453.Peer-Reviewed Original ResearchConceptsT cell responsesAutoimmune T cell responsesT cellsCell responsesB cellsAnti-snRNP antibodiesCross-reactive B cellsNon-autoimmune miceT cell toleranceB-cell processesSera of humansCross-reactive determinantsNative snRNP particlesMouse AgAutoreactive CD4Naive miceAutoantibody responseAutoreactive cellsMurine lupusTh cellsCommon findingSelf-AgCell toleranceMolecular mimicryMice