Featured Publications
Genome-wide association study of psychiatric and substance use comorbidity in Mexican individuals
Martínez-Magaña JJ, Genis-Mendoza AD, Villatoro Velázquez JA, Bustos-Gamiño M, Juárez-Rojop IE, Tovilla-Zarate CA, Sarmiento E, Saucedo E, Rodríguez-Mayoral O, Fleiz-Bautista C, Camarena B, Aguilar A, Gonzalez-Castro TB, Medina-Mora ME, Nicolini H. Genome-wide association study of psychiatric and substance use comorbidity in Mexican individuals. Scientific Reports 2021, 11: 6771. PMID: 33762635, PMCID: PMC7990941, DOI: 10.1038/s41598-021-85881-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAllelesBiological Variation, PopulationComorbidityFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleMental DisordersMiddle AgedPolymorphism, Single NucleotidePublic Health SurveillanceQuantitative Trait LociRisk AssessmentRisk FactorsSubstance-Related DisordersYoung AdultConceptsGenome-wide association studiesGenome-wide correlationSingle nucleotide polymorphismsVertical pleiotropyAssociation studiesWide association signalsGenome-wide associationPolygenic risk scoresQuantitative lociAssociation signalsPhagocytosis pathwayNominal associationTraitsPleiotropyPathwayMeQTLMendelian randomizationGenesLociHigher polygenic risk scoreMicroarrayMultiple logistic modelMexican populationCommon comorbiditiesPolymorphism
2021
Psychiatric Comorbidity in Mexican Adolescents with a Diagnosis of Eating Disorders Its Relationship with the Body Mass Index
Ruiz-Ramos D, Martínez-Magaña JJ, García AR, Juarez-Rojop IE, Gonzalez-Castro TB, Tovilla-Zarate CA, Sarmiento E, López-Narvaez ML, Nicolini H, Genis-Mendoza AD. Psychiatric Comorbidity in Mexican Adolescents with a Diagnosis of Eating Disorders Its Relationship with the Body Mass Index. International Journal Of Environmental Research And Public Health 2021, 18: 3900. PMID: 33917708, PMCID: PMC8068102, DOI: 10.3390/ijerph18083900.Peer-Reviewed Original ResearchConceptsBody mass indexComorbid psychiatric disordersMass indexPsychiatric comorbidityPsychiatric disordersED diagnosisHigher body mass indexMini International Neuropsychiatric InterviewMexican adolescentsPresence of comorbiditiesInternational Neuropsychiatric InterviewMajor depressive disorderBinge-eating disorderChildren/adolescentsPrevalent comorbiditiesNeuropsychiatric InterviewDepressive disorderComorbiditiesGeneral populationDisorder prevalenceSevere metabolic disruptionsIntegrative treatmentMetabolic disruptionSuicide riskPrevalence
2019
Genetic association analysis of 5‐HTR2A gene variants in eating disorders in a Mexican population
Genis‐Mendoza A, Ruiz‐Ramos D, López‐Narvaez M, Tovilla‐Zárate C, García A, Meda G, Martinez‐Magaña J, González‐Castro T, Juárez‐Rojop I, Nicolini H. Genetic association analysis of 5‐HTR2A gene variants in eating disorders in a Mexican population. Brain And Behavior 2019, 9: e01286. PMID: 31199591, PMCID: PMC6625474, DOI: 10.1002/brb3.1286.Peer-Reviewed Original Research