F95. LOCAL ANCESTRY-AWARE META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES FOR ALCOHOL CONSUMPTION IN LATIN AMERICAN POPULATIONS
Martinez-Magana J, Atkinson E, Giusti-Rodriguez P, Santoro M, Wassertheil-Smoller S, Daviglus M, Perreira K, Nicolini H, Pereira A, Belangero S, Moyses-Oliveira M, Tucker K, Ordovas J, Villatoro-Velazquez J, Montalvo-Ortiz J. F95. LOCAL ANCESTRY-AWARE META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES FOR ALCOHOL CONSUMPTION IN LATIN AMERICAN POPULATIONS. European Neuropsychopharmacology 2024, 87: 256. DOI: 10.1016/j.euroneuro.2024.08.506.Peer-Reviewed Original ResearchGenome-wide association studiesGenome-wide association study studiesAncestry-specific effectsIntergenic variantAlcohol consumptionAncestry-specific lociNative-American ancestryFrequency of alcohol consumptionAssociated with alcohol consumptionMeta-analysisLocal ancestryAdmixed populationsGWA studiesGenomic backgroundAssociation studiesSLIT3 geneMAGI1 genesGenomics ConsortiumGenetic associationGenesLatin American populationsAfrican ancestryGenetic liabilityUnited StatesAncestryExploring the relationship between admixture and genetic susceptibility to attention deficit hyperactivity disorder in two Latin American cohorts
Garzón Rodríguez N, Briceño-Balcázar I, Nicolini H, Martínez-Magaña J, Genis-Mendoza A, Flores-Lázaro J, Villatoro Velázquez J, Bustos Gamiño M, Medina-Mora M, Quiroz-Padilla M. Exploring the relationship between admixture and genetic susceptibility to attention deficit hyperactivity disorder in two Latin American cohorts. Journal Of Human Genetics 2024, 69: 373-380. PMID: 38714835, PMCID: PMC11269173, DOI: 10.1038/s10038-024-01246-5.Peer-Reviewed Original ResearchGenome-wide association analysisSingle-nucleotide polymorphismsSingle-nucleotide variantsSingle-nucleotideRisk-associated lociGenome-wide significanceRisk single-nucleotide polymorphismsAttention deficit hyperactivity disorderLocal ancestryAssociation lociIntergenic regionAdmixture proportionsAncestral componentsGenomic ancestryAssociation analysisAncestry levelsEuropean ancestryGenetic associationEuropean componentDeficit hyperactivity disorderAncestryGenomeGenesGenetic susceptibilityHyperactivity disorder