2022
Janus kinase‐signal transducers and activators of transcription (JAK–STAT) activation in anti‐programmed death‐1 (PD‐1) therapy—Associated granuloma annulare: a case series
Choi R, Wang JX, Damsky W, Wang A, Galan A, Leventhal J. Janus kinase‐signal transducers and activators of transcription (JAK–STAT) activation in anti‐programmed death‐1 (PD‐1) therapy—Associated granuloma annulare: a case series. International Journal Of Dermatology 2022, 62: e323-e325. PMID: 35933688, PMCID: PMC9902571, DOI: 10.1111/ijd.16375.Peer-Reviewed Original Research
2019
Janus kinase inhibition induces disease remission in cutaneous sarcoidosis and granuloma annulare
Damsky W, Thakral D, McGeary MK, Leventhal J, Galan A, King B. Janus kinase inhibition induces disease remission in cutaneous sarcoidosis and granuloma annulare. Journal Of The American Academy Of Dermatology 2019, 82: 612-621. PMID: 31185230, PMCID: PMC7590533, DOI: 10.1016/j.jaad.2019.05.098.Peer-Reviewed Original ResearchConceptsGranuloma annulareCutaneous sarcoidosisPathway activationCutaneous granulomatous disordersRecalcitrant cutaneous sarcoidosisSkin biopsy specimensSignal regulatory protein αJAK-STAT pathway activationTranscription (JAK/STAT) pathway activationRegulatory protein αRecalcitrant sarcoidosisSarcoidosis activityDisease remissionConsecutive patientsGranulomatous disorderProspective evaluationBiopsy specimensHistologic resolutionSkin biopsiesMean improvementSarcoidosisImmunohistochemical analysisJAK inhibitorsJAK inhibitionPatients