2024
Lower Risk of Postoperative Complications and Rotator Cuff Retear Associated with Semaglutide Use in Patients with Type II Diabetes Mellitus Undergoing Arthroscopic Rotator Cuff Repair
Seddio A, Moran J, Gouzoulis M, Garbis N, Salazar D, Grauer J, Jimenez A. Lower Risk of Postoperative Complications and Rotator Cuff Retear Associated with Semaglutide Use in Patients with Type II Diabetes Mellitus Undergoing Arthroscopic Rotator Cuff Repair. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2024 PMID: 39490542, DOI: 10.1016/j.arthro.2024.09.057.Peer-Reviewed Original ResearchArthroscopic rotator cuff repairT2DM patientsRotator cuff retearRotator cuff repairElixhauser Comorbidity IndexAdverse eventsLow risk of postoperative complicationsOdds ratioRisk of postoperative complicationsKaplan-Meier survival analysisUrinary tract infectionSurgical-site infectionCuff repairLog-rank testRetrospective comparative studyAcute kidney injuryMinor adverse eventsType II diabetes mellitusAssociated with decreased oddsMultivariate logistic regressionArthroscopic shoulder proceduresII diabetes mellitusAdministrative billing codesPostoperative complicationsTract infectionsFollowing carpel tunnel release, what factors affect whether patients return to the same or different hand surgeon for a subsequent procedure?
Halperin S, Dhodapkar M, Pathak N, Joo P, Luo X, Grauer J. Following carpel tunnel release, what factors affect whether patients return to the same or different hand surgeon for a subsequent procedure? PLOS ONE 2024, 19: e0312159. PMID: 39436931, PMCID: PMC11495619, DOI: 10.1371/journal.pone.0312159.Peer-Reviewed Original ResearchImpact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisAfter Primary Total Shoulder Arthroplasty, Factors Associated with Returning to the Same Surgeon for Subsequent Total Shoulder Arthroplasty
Gouzoulis M, Halperin S, Seddio A, Wilhelm C, Moran J, Donohue K, Jimenez A, Grauer J. After Primary Total Shoulder Arthroplasty, Factors Associated with Returning to the Same Surgeon for Subsequent Total Shoulder Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e24.00117. PMID: 39401371, PMCID: PMC11473060, DOI: 10.5435/jaaosglobal-d-24-00117.Peer-Reviewed Original ResearchConceptsTotal shoulder arthroplastyShoulder arthroplastyAdverse eventsPrimary total shoulder arthroplastyTotal shoulder arthroplasty patientsAnatomic total shoulder arthroplastyPatient satisfactionDepression diagnosisMinority of patientsPostoperative adverse eventsAssociated with decreased oddsRevision TSAFactors associated with returnSame surgeonContralateral surgeryElixhauser Comorbidity IndexIpsilateral shoulderFemale sexComorbidity indexMultivariate analysisRevision surgeryComorbidity burdenPatientsImprove patient satisfactionSurgeonsComparable Overall Risk of Neurologic Adverse Events Following Cervicothoracic Interlaminar and Transforaminal Epidural Injections: An Analysis of 1.29 Million Patients.
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Vasudevan R, Day W, Ratnasamy P, Rubio D, Grauer J. Comparable Overall Risk of Neurologic Adverse Events Following Cervicothoracic Interlaminar and Transforaminal Epidural Injections: An Analysis of 1.29 Million Patients. Spine 2024 PMID: 39394649, DOI: 10.1097/brs.0000000000005181.Peer-Reviewed Original ResearchNeurological adverse eventsAdverse eventsElixhauser Comorbidity IndexNeurological complicationsOdds ratioEpidural spinal injectionsInterlaminar (ILTransforaminal epidural injectionsAssociated with specific complicationsTransforaminal (TFNerve root injuryRisk of complicationsAssociated with higher odds ratiosMultivariate logistic regressionRisk of neurological adverse eventsHigher odds ratioCervical pathologyEpidural hematomaTF injectionSpinal injectionEpidural injectionSpecific complicationsAdult patientsCase reportComorbidity indexPreoperative Anxiety: An Important Risk Factor of Postoperative Adverse Events and Increased Reoperation Rates in Patients Undergoing Single-Level Anterior Cervical Diskectomy and Fusion
Katsnelson B, Rancu A, Winter A, Grauer J. Preoperative Anxiety: An Important Risk Factor of Postoperative Adverse Events and Increased Reoperation Rates in Patients Undergoing Single-Level Anterior Cervical Diskectomy and Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00204. PMCID: PMC11473058, DOI: 10.5435/jaaosglobal-d-24-00204.Peer-Reviewed Original ResearchRevision surgery ratesAnterior cervical diskectomyAdverse eventsACDF patientsCervical diskectomySurgery ratesSingle-level anterior cervical diskectomyAdverse outcomesPreoperative anxietyCervical spine surgeryIncreased reoperation rateAssociated with adverse eventsFusion (ACDFSingle-level ACDFPostoperative adverse eventsPrevalence of mental health disordersImportant risk factorsMultivariate regression analysisReoperation rateMental health disordersSpine surgerySurgical outcomesElixhauser Comorbidity IndexHistory of anxietySurgical proceduresRisk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients
Ratnasamy P, Diatta F, Allam O, Kauke-Navarro M, Grauer J. Risk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients. JAAOS Global Research And Reviews 2024, 8: e24.00040. PMID: 39392934, PMCID: PMC11469891, DOI: 10.5435/jaaosglobal-d-24-00040.Peer-Reviewed Original ResearchConceptsBehcet's syndromeAdverse eventsTotal knee arthroplastyMultivariate analysisRevision surgeryRisk of postoperative complicationsRisk of perioperative adverse eventsTotal hip arthroplastyLog-rank testElixhauser Comorbidity Index scoreRetrospective cohort studyMultisystem autoimmune disorderPostoperative adverse eventsPerioperative adverse eventsComorbidity Index scoreNational administrative databaseKnee arthroplastyTotal knee arthroplasty patientsPostoperative complicationsNo significant differencePatient ageAutoimmune disordersPerioperative managementSyndrome patientsCohort studyRate and Timing of Revision and Contralateral Anterior Cruciate Ligament Reconstruction Relative to Index Surgery
Halperin S, Dhodapkar M, McLaughlin W, Hewett T, Grauer J, Medvecky M. Rate and Timing of Revision and Contralateral Anterior Cruciate Ligament Reconstruction Relative to Index Surgery. Orthopaedic Journal Of Sports Medicine 2024, 12: 23259671241274671. PMID: 39376746, PMCID: PMC11457252, DOI: 10.1177/23259671241274671.Peer-Reviewed Original ResearchAnterior cruciate ligament (ACL) reconstructionContralateral reconstructionRevision ACLRContralateral ACL injuryACL injuryMultivariate logistic regressionLevel of evidenceIpsilateral revisionsCross-sectional studyPatient cohortIpsilateral reconstructionFemale sexMultivariate analysisPatient counselingInjury-prevention programsPatientsTime of revisionYounger ageGraft reinjuryAdministrative databasesLogistic regressionStudy periodACLInjuryPearlDiverPatients with fibromyalgia have increased risk of 90-day postoperative adverse events following arthroscopic rotator cuff repair
Rancu A, Katsnelson B, Sanchez J, Winter A, Vasudevan R, Grauer J. Patients with fibromyalgia have increased risk of 90-day postoperative adverse events following arthroscopic rotator cuff repair. JSES International 2024 DOI: 10.1016/j.jseint.2024.09.018.Peer-Reviewed Original ResearchRotator cuff repairPostoperative adverse eventsAdverse eventsArthroscopic rotator cuff repairCurrent Procedural TerminologyElixhauser Comorbidity IndexOccurrence of wound dehiscenceEmergency departmentUrinary tract infectionSymptomatic rotator cuff tearsAssociated with increased riskCuff repairLog-rank testYear of surgerySurgical site infectionSevere adverse eventsKaplan-Meier curvesAcute kidney injuryOccurrence of sepsisDeep vein thrombosisMinor adverse eventsRotator cuff repair patientsIndividual adverse eventsOdds of ED utilizationDiagnosis of fibromyalgiaDisparities in Dual-energy X-ray Absorptiometry Scan Utilization Across Race/Ethnic Groups Before and After Hip Fractures
Rudisill K, Ratnasamy P, Sanchez J, Grauer J. Disparities in Dual-energy X-ray Absorptiometry Scan Utilization Across Race/Ethnic Groups Before and After Hip Fractures. JAAOS Global Research And Reviews 2024, 8: e24.00052. PMID: 39303221, PMCID: PMC11419421, DOI: 10.5435/jaaosglobal-d-24-00052.Peer-Reviewed Original ResearchConceptsHip fracture populationHip fractureDEXA scanRace/ethnic groupsElixhauser Comorbidity IndexLesser oddsPatient ageFracture populationScan utilizationComorbidity indexTime of hip fractureBefore hip fractureStudy revealed disparitiesImprove medication accessDual x-ray absorptiometryHip fracture patientsGeriatric hip fracturesX-ray absorptiometryHip fragility fracturesMedication accessNon-white categorySentinel eventsHealthcare systemFragility fracturesFracture patients90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. 90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study. JAAOS Global Research And Reviews 2024, 8: e24.00069. PMID: 39330875, PMCID: PMC11412709, DOI: 10.5435/jaaosglobal-d-24-00069.Peer-Reviewed Original ResearchConceptsHip fracture surgeryHip fractureGeriatric patientsFracture surgeryAdverse eventsRate of minor adverse eventsCOVID-19 diagnosisWeeks of surgeryMinor adverse eventsTime pointsAssociated with increased oddsComplication rateAssess complicationsCOVID-19 positivityCOVID-19 infectionMultivariate analysisSurgeryComplicationsPatientsDatabase studyReadmission ratesCare algorithmWeeksDiagnosisCOVID-19Goldenhar syndrome associated with increased risk of respiratory failure and reoperations following spinal deformity surgery
Gouzoulis M, Jabbouri S, Seddio A, Grauer J, Tuason D. Goldenhar syndrome associated with increased risk of respiratory failure and reoperations following spinal deformity surgery. Spine Deformity 2024, 1-6. PMID: 39249241, DOI: 10.1007/s43390-024-00963-3.Peer-Reviewed Original ResearchAdolescent idiopathic scoliosisPosterior spinal fusionGoldenhar syndromeAdverse eventsRespiratory failureSpinal fusionDeformity surgeryIncreasing odds of respiratory failureOdds ratioRisk of respiratory failureOdds of respiratory failureIncidence of adverse eventsIncidence of reoperationSpinal deformity surgeryRisk of adverse eventsSevere adverse eventsPostoperative adverse eventsMultivariate logistic regressionAssociated with scoliosisNational sample of patientsSample of patientsBackgroundGoldenhar syndromeSpinal manifestationsElixhauser Comorbidity IndexPearlDiver databaseTotal Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival.
Gillinov S, Modrak M, Park N, Monahan P, Wilhelm C, Lee M, Mahatme R, Fong S, Moran J, Grauer J, Jimenez A. Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival. Clinical Orthopaedics And Related Research® 2024 PMID: 39246053, DOI: 10.1097/corr.0000000000003209.Peer-Reviewed Original ResearchVenous thromboembolic eventsTotal shoulder arthroplastyHemophilia AImplant survivalMatched controlsThromboembolic eventsElixhauser Comorbidity IndexMale patientsAdverse eventsShoulder arthroplastyProsthesis survivalThromboembolic adverse eventsVenous thromboembolic event prophylaxisKaplan-Meier analysisFactor VIII levelsRevers total shoulder arthroplastyIndividual patient basisOdds of postoperative bleedingPostoperative bleedingBleeding complicationsTranexamic acidNinety-dayPatient basisControl cohortComorbidity indexP27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsisP116. National trends and risk factors for new-onset depression following posterior lumbar fusion
Day W, Gouzoulis M, Zhu J, Seddio A, Fourman M, Grauer J. P116. National trends and risk factors for new-onset depression following posterior lumbar fusion. The Spine Journal 2024, 24: s119. DOI: 10.1016/j.spinee.2024.06.138.Peer-Reviewed Original ResearchNew-onset depressionPosterior lumbar fusionNational administrative claims databaseSingle-level posterior lumbar fusionRisk factorsDevelopment of new-onset depressionAdministrative claims databasePostoperative complicationsLumbar fusionNational trendsFactors associated with patientsClaims databaseAggregate patient dataAdult patientsTarget risk mitigation strategiesMultivariate logistic regressionPsychiatric risk factorsPotential risk factorsElixhauser Comorbidity IndexPercentage of patientsHigher oddsCase-controlAlcohol/drug abuseDiagnosis of tumorsLogistic regressionP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age117. Opioid prescription patterns following single-level lumbar discectomy: a national database study
Rancu A, Gouzoulis M, Winter A, Katsnelson B, Ansah-Twum J, Grauer J. 117. Opioid prescription patterns following single-level lumbar discectomy: a national database study. The Spine Journal 2024, 24: s60-s61. DOI: 10.1016/j.spinee.2024.06.560.Peer-Reviewed Original ResearchMorphine milligram equivalentsSingle-level lumbar discectomyMedian morphine milligram equivalentsOpioid prescriptionsLumbar discectomyPrescribed morphine milligram equivalentsDiagnosis of chronic painPostoperative opioid prescriptionsOpioid prescribing patternsOpioid prescription patternsPostoperative pain controlPostoperative pain managementProportion of patientsNational database studyMultivariate linear regression analysisWilcoxon rank sum testDiagnosis of neoplasmsMultivariate logistic regressionRank sum testExcess opioidsPrescription percentageMilligram equivalentsPostoperative opioidsChronic painSpine procedures100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetesAnatomic and reverse total shoulder arthroplasty: variables affecting 90-day overall reimbursement
Halperin S, Dhodapkar M, Modrak M, Donohue K, Medvecky M, Grauer J. Anatomic and reverse total shoulder arthroplasty: variables affecting 90-day overall reimbursement. Seminars In Arthroplasty JSES 2024, 34: 564-570. DOI: 10.1053/j.sart.2024.02.007.Peer-Reviewed Original ResearchAnatomic total shoulder arthroplastyReverse total shoulder arthroplastyTotal shoulder arthroplastyTotal shoulder arthroplasty patientsPostoperative eventsShoulder arthroplastyPatient demographicsOverall reimbursementSurgery typeAdverse eventsMale sexAssociated with reimbursementMultivariate linear regressionOncological diagnosisEmergency department visitsPatientsOrthopedic proceduresEffective procedureAdministrative databasesHospital readmissionInsurance typeSurgeryReduce healthcare expendituresDepartment visitsIncreased frequency