2023
Incidental Durotomy After Posterior Lumbar Decompression Surgery Associated With Increased Risk for Venous Thromboembolism
Gouzoulis M, Joo P, Caruana D, Kammien A, Rubio D, Grauer J. Incidental Durotomy After Posterior Lumbar Decompression Surgery Associated With Increased Risk for Venous Thromboembolism. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: e445-e450. PMID: 36727948, DOI: 10.5435/jaaos-d-22-00917.Peer-Reviewed Original ResearchMeSH KeywordsAdultDecompressionHumansIncidencePulmonary EmbolismRetrospective StudiesRisk FactorsVenous ThromboembolismConceptsLumbar decompression surgeryPosterior lumbar decompression surgeryRisk of VTEVenous thromboembolismIncidental durotomyDecompression surgeryMultivariate analysisOdds of VTETiming of VTEMore VTEDecompression patientsDurotomy groupPatient demographicsPulmonary embolismAdult patientsDegenerative etiologyBed restLumbar laminectomyPatient recoveryUnivariate analysisSpinal surgeryAdministrative codingDurotomySurgeryPatients
2022
Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study
Joo P, Modrak M, Park N, Brand J, Rubin L, Grauer J, Bernstein J. Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study. JAAOS Global Research And Reviews 2022, 6: e22.00228. PMID: 36732301, PMCID: PMC9746777, DOI: 10.5435/jaaosglobal-d-22-00228.Peer-Reviewed Original ResearchConceptsHip fracture surgeryFracture surgeryAdverse eventsOdds ratioProphylactic agentGreater oddsAnticoagulant-naïve patientsDifferent anticoagulant agentsVenous thromboembolism chemoprophylaxisVTE prophylactic agentNational database studyDistal femoral fracturesCoumadin groupLower transfusionVTE prophylaxisVTE ratesPatient characteristicsComorbidity profilesFemoral fracturesChemoprophylactic agentAnticoagulant agentsCoumadinDatabase studyLower oddsPatientsRisk factors for venous thromboembolism following fractures isolated to the foot and ankle fracture
Gouzoulis MJ, Joo PY, Kammien AJ, McLaughlin WM, Yoo B, Grauer JN. Risk factors for venous thromboembolism following fractures isolated to the foot and ankle fracture. PLOS ONE 2022, 17: e0276548. PMID: 36264985, PMCID: PMC9584400, DOI: 10.1371/journal.pone.0276548.Peer-Reviewed Original ResearchMeSH KeywordsAnkle FracturesAnkle InjuriesAnticoagulantsFoot InjuriesHumansMalePulmonary EmbolismRetrospective StudiesRisk FactorsVenous ThromboembolismConceptsVenous thromboembolismAnkle fracturesFactor V LeidenSurgical treatmentRisk factorsActive cancerV LeidenTiming of VTEPrior venous thromboembolismIsolated footIndependent risk factorDeep vein thrombosisRisk/benefit considerationsMultivariate logistical regressionSpecific fracture patternsElixhauser indexPulmonary embolismVein thrombosisPearlDiver databaseMetatarsal fracturesAppendicular fracturesMale sexSuch injuriesTraumatic injuryChi-square analysisTotal Hip Arthroplasty in Patients With Classic Hemophilia: A Matched Comparison of 90-Day Outcomes and 5-Year Implant Survival
Gillinov SM, Burroughs PJ, Moore HG, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Classic Hemophilia: A Matched Comparison of 90-Day Outcomes and 5-Year Implant Survival. The Journal Of Arthroplasty 2022, 37: 1333-1337. PMID: 35257821, PMCID: PMC9177736, DOI: 10.1016/j.arth.2022.02.107.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyNon-hemophilia patientsMinor adverse eventsSerious adverse eventsAdverse eventsClassic hemophiliaHaemophilia patientsImplant survivalHip arthroplastyGreater oddsMultivariate analysisFive-year implant survivalPrimary total hip arthroplastyAcute kidney injuryVenous thromboembolism prophylaxisElixhauser Comorbidity IndexKaplan-Meier analysisEvidence-based guidelinesThromboembolism prophylaxisVTE prophylaxisComorbidity indexKidney injuryTHA patientsFactor replacementRetrospective study
2021
Risk Factors for Venous Thromboembolism in Children Undergoing Orthopedic Surgery.
Mets EJ, Pathak N, Galivanche AR, McLynn RP, Frumberg DB, Grauer JN. Risk Factors for Venous Thromboembolism in Children Undergoing Orthopedic Surgery. Orthopedics 2021, 45: 31-37. PMID: 34846239, DOI: 10.3928/01477447-20211124-06.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolHumansMaleOrthopedic ProceduresOrthopedicsPostoperative ComplicationsRetrospective StudiesRisk FactorsVenous ThromboembolismConceptsVenous thromboembolismAdverse eventsRisk factorsOrthopedic surgeryNational Surgical Quality Improvement Program Pediatric databaseSurgeons National Surgical Quality Improvement Program Pediatric databaseIncidence of VTEPostoperative venous thromboembolismMinor adverse eventsPostoperative adverse eventsPreoperative blood transfusionIndependent risk factorMajor adverse eventsHigh-risk subpopulationsVTE prophylaxisPerioperative outcomesPatient demographicsBlood transfusionPatient factorsPediatric patientsSurgical variablesPreventable complicationsFemur fracturesPatient populationRetrospective analysis
2018
Thromboembolic Events After Traumatic Vertebral Fractures
Samuel AM, Diaz-Collado PJ, Gala RJ, Webb ML, Lukasiewicz AM, Basques BA, Bohl DD, Kim HJ, Grauer JN. Thromboembolic Events After Traumatic Vertebral Fractures. Spine 2018, 43: 1289-1295. PMID: 29538240, DOI: 10.1097/brs.0000000000002634.Peer-Reviewed Original ResearchConceptsVenous thromboembolism eventsTraumatic vertebral fracturesVertebral fracturesSpinal cord injuryOdds ratioCord injuryRisk factorsNational Trauma Data Bank Research Data SetLonger inpatient lengthPulmonary embolism eventsDeep vein thrombosisHigh-energy injuriesVertebral fracture patientsLength of stayAdditional risk factorsMultivariate logistic regressionSuch adverse outcomesOverall rateThromboembolism eventsHospital courseThromboembolic eventsFracture patientsVein thrombosisLonger LOSTrauma patientsLonger Operative Time Is Associated With Increased Adverse Events After Anterior Cervical Diskectomy and Fusion: 15-Minute Intervals Matter.
Ondeck NT, Bohl DD, McLynn RP, Cui JJ, Bovonratwet P, Singh K, Grauer JN. Longer Operative Time Is Associated With Increased Adverse Events After Anterior Cervical Diskectomy and Fusion: 15-Minute Intervals Matter. Orthopedics 2018, 41: e483-e488. PMID: 29708570, DOI: 10.3928/01477447-20180424-02.Peer-Reviewed Original ResearchConceptsAnterior cervical diskectomyOperative timeAdverse eventsCervical diskectomyPerioperative outcomesSurgical durationSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramIndividual adverse outcomesPostoperative adverse eventsLonger operative timeGreater operative timeQuality Improvement ProgramUnplanned intubationHospital stayBaseline characteristicsVenous thromboembolismHospital readmissionAdverse outcomesPatient variablesAmerican CollegeAnesthetic effectSurgical pathologyPhysiologic stress
2017
Risk factors and pharmacologic prophylaxis for venous thromboembolism in elective spine surgery
McLynn RP, Diaz-Collado PJ, Ottesen TD, Ondeck NT, Cui JJ, Bovonratwet P, Shultz BN, Grauer JN. Risk factors and pharmacologic prophylaxis for venous thromboembolism in elective spine surgery. The Spine Journal 2017, 18: 970-978. PMID: 29056565, DOI: 10.1016/j.spinee.2017.10.013.Peer-Reviewed Original ResearchConceptsElective spine surgeryPrior venous thromboembolismPharmacologic prophylaxisVenous thromboembolismAssociation of patientSpine surgeryRisk factorsUnfractionated heparinVTE prophylaxisInstitutional cohortNational Surgical Quality Improvement Program databaseElective spine surgery patientsRate of VTEQuality Improvement Program databaseDependent functional statusPerioperative blood transfusionRetrospective cohort studySpine surgery patientsImprovement Program databaseIndependent risk factorRetrospective cohort analysisIncidence of hematomaLonger operative timeLumbar spine surgerySingle-institution cohort