2024
Prediction Models for Risk Assessment of Surgical Site Infection after Spinal Surgery: A Systematic Review
Lauinger A, Blake S, Fullenkamp A, Polites G, Grauer J, Arnold P. Prediction Models for Risk Assessment of Surgical Site Infection after Spinal Surgery: A Systematic Review. North American Spine Society Journal (NASSJ) 2024, 100518. DOI: 10.1016/j.xnsj.2024.100518.Peer-Reviewed Original ResearchSurgical site infectionPreoperative risk modelSpinal surgerySite infectionAdverse eventsAssessment of surgical site infectionACS NSQIP surgical risk calculatorPostoperative surgical site infectionNSQIP surgical risk calculatorRate of adverse eventsSpine surgery patientsRisk of adverse eventsStratify patient riskSurgical risk calculatorField of spine surgeryClinical prediction toolSpine surgeryRisk modelSurgery patientsSurgeryAddressing factorsPatient riskClinical utilitySystematic reviewUnique susceptibilityIncreased Risk of 90-Day Complications in Patients With Fibromyalgia Undergoing Total Shoulder Arthroplasty
Sanchez J, Rancu A, Diatta F, Jonnalagadda A, Dhodapkar M, Knoedler L, Kauke-Navarro M, Grauer J. Increased Risk of 90-Day Complications in Patients With Fibromyalgia Undergoing Total Shoulder Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e24.00102. PMID: 38722914, PMCID: PMC11081627, DOI: 10.5435/jaaosglobal-d-24-00102.Peer-Reviewed Original ResearchConceptsRevision-free survivalDay of surgeryAdverse eventsTSA patientsIncreased riskMultivariate analysisOdds ratioIncreased risk of adverse eventsUrinary tract infectionLog-rank testRisk of adverse eventsSurgical site infectionSevere adverse eventsEffective treatment optionAcute kidney injuryDeep vein thrombosisMinor adverse eventsNon-fibromyalgia patientsEnd-stage glenohumeral osteoarthritisAssociation of fibromyalgiaIncreased odds ratioTotal shoulder arthroplastyShoulder infectionPulmonary embolismTract infectionsCefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion
Dhodapkar M, Jeong S, Halperin S, Rubio D, Li M, Grauer J. Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00082. PMCID: PMC11068128, DOI: 10.5435/jaaosglobal-d-24-00082.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSurgical site infectionElixhauser Comorbidity IndexLumbar fusionAntibiotic prophylaxisAdverse outcomesAntibiotic prophylaxis regimenAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisRevision ratePerioperative antibiotic prophylaxisPostoperative adverse outcomesPosterior lumbar fusion patientsMultivariate logistic regressionProphylaxis regimensProphylaxis regimenPatient ageSite infectionUnivariate analysisCefazolinComorbidity indexMultivariate analysisAntibiotic subgroupsTraumatic diagnosesSurgical site infection following isolated lumbar discectomy increases odds of revision lumbar surgery within first 6 months, but not beyond
Kim L, Halperin S, Grauer J. Surgical site infection following isolated lumbar discectomy increases odds of revision lumbar surgery within first 6 months, but not beyond. The Spine Journal 2024, 24: 1459-1466. PMID: 38570035, DOI: 10.1016/j.spinee.2024.03.017.Peer-Reviewed Original ResearchSurgical site infectionRevision lumbar surgeryLumbar discectomyLumbar surgeryElixhauser Comorbidity IndexSite infectionFactors associated with surgical site infectionPreoperative diagnosis of infectionIncidence of secondary surgeryLumbar discectomy patientsDiagnosis of infectionMultivariate logistic regressionPreoperative diagnosisDiscectomy patientsPostoperative complicationsIndex surgeryPatient ageSecondary surgerySpinal surgeryIndependent predictorsAdult patientsLumbar fusionPerforming surgeryDiscectomyI&DAdverse Events After Isolated Posterior Cruciate Ligament Reconstruction: A National Database Study
Kammien A, Price R, McLaughlin W, Park N, Richter D, Schenck R, Grauer J, Medvecky M. Adverse Events After Isolated Posterior Cruciate Ligament Reconstruction: A National Database Study. Orthopaedic Journal Of Sports Medicine 2024, 12: 23259671231222123. PMID: 38249782, PMCID: PMC10798085, DOI: 10.1177/23259671231222123.Peer-Reviewed Original ResearchRate of adverse eventsSurgical site infectionIsolated PCL reconstructionAdverse eventsPCL reconstructionPulmonary embolismSite infectionCompartment syndromePosterior cruciate ligamentVariable rates of complicationsOdds ratioVascular eventsOptimal managementIsolated posterior cruciate ligament reconstructionConcomitant ligament surgeryEmergency departmentNational cohortDeep vein thrombosesRate of complicationsElixhauser Comorbidity Index scoreDay of surgeryDeep vein thrombosisCalculate odds ratiosPosterior cruciate ligament reconstructionComorbidity Index score
2023
Wide-Awake Carpal Tunnel Release in the United States: Trends in Volume and Reimbursement by Operative Setting
Kammien A, Kim S, Mookerjee V, Williams M, Prsic A, Grauer J, Colen D. Wide-Awake Carpal Tunnel Release in the United States: Trends in Volume and Reimbursement by Operative Setting. Plastic & Reconstructive Surgery 2023, 154: 143-149. PMID: 37535704, DOI: 10.1097/prs.0000000000010961.Peer-Reviewed Original ResearchSurgical site infectionOffice-based surgeryCarpal tunnel releaseNarcotic prescriptionsOffice surgeryPhysician reimbursementOperating roomPercent of surgeriesWide-awake surgeryEmergency department visitsNational administrative databaseFinancial burdenComorbidity burdenPrimary endpointAdverse eventsED visitsDepartment visitsSite infectionLinear regression modelingSimilar incidenceAdministrative databasesOffice patientsSurgerySurgical settingCommercial insuranceWide Awake Trigger Finger Releases Performed in the United States
Mookerjee V, Kammien A, Prsic A, Grauer J, Colen D. Wide Awake Trigger Finger Releases Performed in the United States. Annals Of Plastic Surgery 2023, 91: 220-224. PMID: 37489963, DOI: 10.1097/sap.0000000000003646.Peer-Reviewed Original ResearchConceptsTrigger finger releaseSurgical site infectionNarcotic prescriptionsED visitsOffice procedureFinger releaseOperating roomPostoperative ED visitsEmergency department visitsDay of surgeryElixhauser Comorbidity IndexPhysician reimbursementOutpatient operating roomComorbidity indexPatient characteristicsPostoperative recordsSite infectionDepartment visitsInpatient surgeryHand surgeryExclusion criteriaSurgeryTotal reimbursementVisitsLower ratesThe correlation of psoriasis and its treatment medications with lumbar discectomy postoperative infections
Day W, Ch'en P, Ratnasamy P, Jeong S, Varthi A, Grauer J. The correlation of psoriasis and its treatment medications with lumbar discectomy postoperative infections. The Spine Journal 2023, 23: 1623-1629. PMID: 37355045, DOI: 10.1016/j.spinee.2023.06.392.Peer-Reviewed Original ResearchSurgical site infectionRisk of SSIPostoperative surgical site infectionElixhauser Comorbidity IndexMultivariable logistic regressionTopical therapyComorbidity indexReoperation rateSite infectionTreatment medicationsMultivariable analysisDiscectomy patientsGreater oddsFive-Year Reoperation RatesSingle-level lumbar discectomyLogistic regressionCorrelation of psoriasisOral systemic treatmentInfection-related complicationsAdministrative database studyDay of surgeryLog-rank testNational administrative databaseRetrospective case controlUS adult populationSingle-level Anterior Cervical Discectomy and Fusion Results in Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort
Jayaram R, Joo P, Gouzoulis M, Ratnasamy P, Caruana D, Grauer J. Single-level Anterior Cervical Discectomy and Fusion Results in Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort. Spine 2023, 48: 1266-1271. PMID: 37339256, DOI: 10.1097/brs.0000000000004754.Peer-Reviewed Original ResearchConceptsPosterior cervical foraminotomySingle-level ACDFSingle-level anterior cervical discectomyPerioperative adverse eventsAnterior cervical discectomyAdverse eventsCervical foraminotomyCervical discectomyRevision rateOdds ratioShort-term adverse eventsSimilar short-term outcomesKaplan-Meier survival analysisRetrospective cohort studySerious adverse eventsCervical disc diseaseFive-year ratesSurgical site infectionShort-term outcomesMultivariable logistic regressionLarge national cohortCumulative revision rateCervical reoperationPCF cohortCohort studyTiming of Adverse Events Within 90 Days of Hip Fracture Surgery: A Database Study
Kammien A, Ratnasamy P, Caruana D, Grauer J. Timing of Adverse Events Within 90 Days of Hip Fracture Surgery: A Database Study. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: 245-251. PMID: 36821080, DOI: 10.5435/jaaos-d-22-00368.Peer-Reviewed Original ResearchConceptsHip fracture surgeryTime of diagnosisAdverse eventsFracture surgeryDay 31Hip fracture surgery patientsElixhauser comorbidity index scoreAcute kidney injuryCommon adverse eventsComorbidity Index scorePatients 65 yearsPostoperative day 0Surgical site infectionUrinary tract infectionPostoperative day 30Specific adverse eventsKidney injuryCardiac eventsSurgery patientsTract infectionsVenous thromboembolismSite infectionPatient counselingNotable morbidityDatabase studyPostoperative Antibiotics Following Reduction Mammaplasty Does Not Reduce Rates of Surgical Site Infection
Mookerjee V, Kammien A, Prassinos A, Grauer J, Butler P. Postoperative Antibiotics Following Reduction Mammaplasty Does Not Reduce Rates of Surgical Site Infection. Aesthetic Surgery Journal 2023, 43: np494-np499. PMID: 36788713, DOI: 10.1093/asj/sjad030.Peer-Reviewed Original ResearchConceptsRate of SSISurgical site infectionBody mass indexReduction mammaplasty patientsPostoperative antibioticsPerioperative antibioticsED visitsSSI ratesSite infectionObese populationReduction mammaplastyPostoperative antibiotic useElixhauser Comorbidity IndexEmergency department visitsSubgroup of patientsPostoperative prescriptionComorbidity indexObese patientsPostoperative courseDepartment visitsMass indexAntibiotic utilizationSubgroup analysisAntibiotic useHigh risk
2022
Postoperative spine surgical site infections: high rate of failure of one-stage irrigation and debridement
Dhodapkar M, Galivanche A, Halperin S, Elaydi A, Rubio D, Grauer J. Postoperative spine surgical site infections: high rate of failure of one-stage irrigation and debridement. The Spine Journal 2022, 23: 484-491. PMID: 36549456, DOI: 10.1016/j.spinee.2022.12.005.Peer-Reviewed Original ResearchConceptsSurgical site infectionElective spine surgerySpine surgeryInitial managementRate of SSIInfection characteristicsSpine surgical site infectionPostoperative surgical site infectionRetrospective case-control studyPresence of bacteremiaRisk stratification toolCase-control studySingle academic institutionTimes greater oddsDevastating complicationSite infectionMultivariable analysisStratification toolSurgical managementSurgical variablesIndex procedureSurgical interventionRisk factorsInclusion criteriaLarge cohortTotal shoulder arthroplasty: ninety-day adverse events and 5-year implant survival in patients with hidradenitis suppurativa
Gouzoulis M, Ratnasamy P, Caruana D, Wiznia D, Medvecky M, Grauer J. Total shoulder arthroplasty: ninety-day adverse events and 5-year implant survival in patients with hidradenitis suppurativa. Seminars In Arthroplasty JSES 2022, 32: 676-680. DOI: 10.1053/j.sart.2022.07.012.Peer-Reviewed Original ResearchTotal shoulder arthroplastySurgical site infectionMinor adverse eventsAdverse eventsSite infectionTSA patientsImplant survivalHS patientsSkin lesionsLog-rank Mantel-Cox testFive-year implant survivalKaplan-Meier survival curvesHigher comorbidity burdenMethods Adult patientsNon-HS groupsSevere adverse eventsElixhauser Comorbidity IndexChronic skin disorderPotential risk factorsMantel-Cox testRisk of infectionComorbidity burdenComorbidity indexPostoperative complicationsReoperation rateHidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty
Gouzoulis MJ, Kammien AJ, Caruana DL, Wiznia DH, Grauer JN. Hidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty. Arthroplasty Today 2022, 16: 169-174. PMID: 35789782, PMCID: PMC9249970, DOI: 10.1016/j.artd.2022.05.013.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyAdverse eventsHS patientsImplant survivalSkin lesionsKaplan-Meier survival curvesNon-HS patientsSurgical site infectionElixhauser Comorbidity IndexInflammatory skin lesionsSpecific adverse eventsLog-rank testPotential risk factorsTotal joint arthroplastyWound-related issuesRisk of woundComorbidity indexAdult patientsSite infectionDegenerative etiologyWound dehiscenceKnee arthroplastyRevision rateRisk factorsAdverse Events After Posterior Lumbar Fusion Are Not Sufficiently Characterized With 30-day Follow-up: A Database Study
Kammien AJ, Zhu JR, Gillinov SM, Gouzoulis MJ, Grauer JN. Adverse Events After Posterior Lumbar Fusion Are Not Sufficiently Characterized With 30-day Follow-up: A Database Study. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 30: 528-533. PMID: 35234736, DOI: 10.5435/jaaos-d-21-01121.Peer-Reviewed Original ResearchConceptsPosterior lumbar fusionTime of diagnosisAdverse eventsLumbar fusionIndividual adverse outcomesNinety-day ratesAcute kidney injurySurgical site infectionUrinary tract infectionSpecific adverse eventsMultiple adverse eventsPLF patientsKidney injuryCardiac eventsTract infectionsVenous thromboembolismPostoperative periodSite infectionAdverse outcomesPatient counselingAdministrative data setsDatabase studyDay 0Time pointsInterquartile range
2021
Ambulatory Single-level Posterior Cervical Foraminotomy for Cervical Radiculopathy
Bovonratwet P, Retzky JS, Chen AZ, Ondeck NT, Samuel AM, Qureshi SA, Grauer JN, Albert TJ. Ambulatory Single-level Posterior Cervical Foraminotomy for Cervical Radiculopathy. Clinical Spine Surgery A Spine Publication 2021, 35: e306-e313. PMID: 34654773, DOI: 10.1097/bsd.0000000000001252.Peer-Reviewed Original ResearchConceptsSingle-level posterior cervical foraminotomyPosterior cervical foraminotomyCervical radiculopathyInpatient proceduresCervical foraminotomyPerioperative complicationsAmbulatory proceduresSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databasePropensity scoreRetrospective cohort comparison studyImprovement Program databaseSurgical site infectionCohort comparison studyHospital lengthPain controlPerioperative outcomesPostoperative complicationsThromboembolic eventsWound complicationsNSQIP databasePatient characteristicsSite infectionIndividual complicationsTotal Joint Arthroplasty in Patients With Achondroplasia: Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Schneble CA, Kahan JB, Polkowski GG, Rubin LE, Grauer JN. Total Joint Arthroplasty in Patients With Achondroplasia: Comparison of 90-Day Adverse Events and 5-Year Implant Survival. Arthroplasty Today 2021, 11: 151-156. PMID: 34584919, PMCID: PMC8452593, DOI: 10.1016/j.artd.2021.08.011.Peer-Reviewed Original ResearchTotal joint arthroplastyAdverse eventsImplant survivalJoint arthroplastyFive-year implant survivalShort-term adverse eventsPrimary total hipSurgical site infectionLong-term implant successMultivariate logistic regressionTotal knee arthroplastyCommon skeletal dysplasiaMedical comorbiditiesSite infectionTotal hipPatient populationKnee arthroplastyAdministrative databasesHigher oddsLarge cohortGreater oddsPatientsImplant successSurvival curvesArthroplasty
2020
Local antibiotics in posterior lumbar fusion procedures for neuromuscular scoliosis: a case for their use
Ondeck NT, Ondeck MA, Bovonratwet P, Albert TJ, Grauer JN. Local antibiotics in posterior lumbar fusion procedures for neuromuscular scoliosis: a case for their use. The Spine Journal 2020, 21: 664-670. PMID: 33347970, DOI: 10.1016/j.spinee.2020.12.004.Peer-Reviewed Original ResearchConceptsSurgical site infectionPosterior spinal fusionNeuromuscular scoliosisLocal antibioticsIntraoperative antibioticsStudy populationRisk of SSIOccurrence of SSIReduced surgical site infectionsHigh-risk patient populationPosterior lumbar fusion proceduresAdverse outcome variablesIncreased overall riskHigh-risk patientsOverall study populationRisk patient populationPatient demographic factorsEntire study populationLumbar fusion proceduresIntrawound antibioticsNMS patientsRenal complicationsRisk patientsPediatric patientsRetrospective review
2017
What Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty?
Bohl DD, Ondeck NT, Basques BA, Levine BR, Grauer JN. What Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty? Clinical Orthopaedics And Related Research® 2017, 475: 2952-2959. PMID: 28054326, PMCID: PMC5670043, DOI: 10.1007/s11999-016-5224-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overArthroplasty, Replacement, HipArthroplasty, Replacement, KneeData MiningDatabases, FactualHumansLength of StayMiddle AgedMultivariate AnalysisPatient DischargePostoperative ComplicationsProcess Assessment, Health CareProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsTotal joint arthroplastyAdverse eventsDays of diagnosisDeep vein thrombosisPulmonary embolismPostoperative dayVein thrombosisMyocardial infarctionJoint arthroplastySurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramMultivariate Cox proportional hazardsSurgical Quality Improvement ProgramMedian postoperative dayPulmonary embolism 3Postoperative adverse eventsSurgical site infectionMyocardial infarction 3Different adverse eventsRetrospective database analysisLife-threatening findingsCertain adverse eventsCox proportional hazardsSuch adverse eventsQuality Improvement ProgramOf 20,376 Lumbar Discectomies, 2.6% of Patients Readmitted Within 30 Days
Webb ML, Nelson SJ, Save A, Cui J, Lukasiewicz AM, Samuel AM, Diaz-Collado PJ, Bohl DD, Ondeck NT, McLynn RP, Grauer JN. Of 20,376 Lumbar Discectomies, 2.6% of Patients Readmitted Within 30 Days. Spine 2017, 42: 1267-1273. PMID: 27926671, DOI: 10.1097/brs.0000000000002014.Peer-Reviewed Original ResearchConceptsSurgical site infectionLumbar discectomyThromboembolic eventsHospital readmissionSite infectionSurgical variablesCommon reasonSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseCauses of readmissionHigher American SocietyImprovement Program databaseRetrospective cohort studyDay of surgeryQuality-based reimbursementQuality improvement initiativesPearson chi-squareAnesthesiologists classPostoperative painPatient demographicsCohort studyOperative timeAffordable Care ActRisk factors