2024
P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsisIncreased Risk of 90-Day Complications in Patients With Fibromyalgia Undergoing Total Shoulder Arthroplasty
Sanchez J, Rancu A, Diatta F, Jonnalagadda A, Dhodapkar M, Knoedler L, Kauke-Navarro M, Grauer J. Increased Risk of 90-Day Complications in Patients With Fibromyalgia Undergoing Total Shoulder Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e24.00102. PMID: 38722914, PMCID: PMC11081627, DOI: 10.5435/jaaosglobal-d-24-00102.Peer-Reviewed Original ResearchConceptsRevision-free survivalDay of surgeryAdverse eventsTSA patientsIncreased riskMultivariate analysisOdds ratioIncreased risk of adverse eventsUrinary tract infectionLog-rank testRisk of adverse eventsSurgical site infectionSevere adverse eventsEffective treatment optionAcute kidney injuryDeep vein thrombosisMinor adverse eventsNon-fibromyalgia patientsEnd-stage glenohumeral osteoarthritisAssociation of fibromyalgiaIncreased odds ratioTotal shoulder arthroplastyShoulder infectionPulmonary embolismTract infectionsAnatomic vs. reverse total shoulder arthroplasty: usage trends and perioperative outcomes
Halperin S, Dhodapkar M, Kim L, Modrak M, Medvecky M, Donohue K, Grauer J. Anatomic vs. reverse total shoulder arthroplasty: usage trends and perioperative outcomes. Seminars In Arthroplasty JSES 2024, 34: 91-96. DOI: 10.1053/j.sart.2023.08.014.Peer-Reviewed Original ResearchTotal shoulder arthroplastyElixhauser Comorbidity IndexPerioperative outcomesAdverse eventsSurgeon volumeShoulder arthroplastyHigher Elixhauser comorbidity indexPerioperative adverse eventsSevere adverse eventsUrinary tract infectionCommon orthopaedic proceduresMatching of patientsPatient demographicsTract infectionsPearlDiver databaseMultivariable analysisOverall incidencePatient populationKidney infectionMerit further investigationOrthopedic proceduresGreater oddsRTSAIncreased percentagePatients
2023
Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease
Dhodapkar M, Halperin S, Saifi C, Whang P, Grauer J, Varthi A. Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease. The Spine Journal 2023, 24: 807-811. PMID: 38081460, DOI: 10.1016/j.spinee.2023.11.025.Peer-Reviewed Original ResearchPosterior lumbar interbody fusionSingle-level posterior lumbar interbody fusionSickle cell diseaseElixhauser Comorbidity IndexAdverse eventsPostoperative outcomesInterbody fusionOdds ratioCell diseaseDays adverse eventsMinor adverse eventsPostoperative adverse eventsPerioperative adverse eventsSevere adverse eventsCohort of patientsED visit ratesEmergency department visitsMultivariable logistic regressionNational administrative databaseRetrospective database studyLumbar interbody fusionSingle level posteriorComorbidity indexPLIF patientsAdult patientsAdverse Events After Ankle Fracture Open Reduction Internal Fixation Among Patients With and Without Documented Cannabis and Tobacco Use
Dhodapkar M, Oghenesume O, Halperin S, Modrak M, Yoo B, Grauer J. Adverse Events After Ankle Fracture Open Reduction Internal Fixation Among Patients With and Without Documented Cannabis and Tobacco Use. Foot & Ankle International 2023, 44: 941-948. PMID: 37698277, DOI: 10.1177/10711007231189698.Peer-Reviewed Original ResearchConceptsOpen reduction internal fixationAnkle fracture open reduction internal fixationUrinary tract infectionMinor adverse eventsAdverse eventsReduction internal fixationRetrospective database studyTobacco useAnkle fracturesInternal fixationTobacco usersHigher oddsDatabase studyGreater oddsAnkle open reduction internal fixationElixhauser comorbidity index scoreCause adverse eventsComorbidity Index scoreSevere adverse eventsCommon orthopedic injuriesMultivariable logistic regressionStudy inclusion criteriaGroup of nonusersPerioperative outcomesAdult patients
2022
Total shoulder arthroplasty: ninety-day adverse events and 5-year implant survival in patients with hidradenitis suppurativa
Gouzoulis M, Ratnasamy P, Caruana D, Wiznia D, Medvecky M, Grauer J. Total shoulder arthroplasty: ninety-day adverse events and 5-year implant survival in patients with hidradenitis suppurativa. Seminars In Arthroplasty JSES 2022, 32: 676-680. DOI: 10.1053/j.sart.2022.07.012.Peer-Reviewed Original ResearchTotal shoulder arthroplastySurgical site infectionMinor adverse eventsAdverse eventsSite infectionTSA patientsImplant survivalHS patientsSkin lesionsLog-rank Mantel-Cox testFive-year implant survivalKaplan-Meier survival curvesHigher comorbidity burdenMethods Adult patientsNon-HS groupsSevere adverse eventsElixhauser Comorbidity IndexChronic skin disorderPotential risk factorsMantel-Cox testRisk of infectionComorbidity burdenComorbidity indexPostoperative complicationsReoperation rate
2018
What Associations Exist Between Comorbidity Indices and Postoperative Adverse Events After Total Shoulder Arthroplasty?
Fu MC, Ondeck NT, Nwachukwu BU, Garcia GH, Gulotta LV, Verma NN, Grauer JN. What Associations Exist Between Comorbidity Indices and Postoperative Adverse Events After Total Shoulder Arthroplasty? Clinical Orthopaedics And Related Research® 2018, 477: 881-890. PMID: 30614913, PMCID: PMC6437372, DOI: 10.1097/corr.0000000000000624.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramBody mass indexTotal shoulder arthroplastyPostoperative adverse eventsComorbidity indexAdverse eventsHighest AUCShoulder arthroplastyAnthropometric variablesSurgical Quality Improvement ProgramReverse total shoulder arthroplastyDiscriminative abilityCharlson Comorbidity IndexThirty-day outcomesSevere adverse eventsPreoperative risk stratificationModerate discriminative abilityYears of ageQuality Improvement ProgramGood discriminative abilityGreater associationCombination of ageAnesthesiologists classificationASA scoreMedical comorbiditiesPredicting Adverse Outcomes After Total Hip Arthroplasty: A Comparison of Demographics, the American Society of Anesthesiologists class, the Modified Charlson Comorbidity Index, and the Modified Frailty Index.
Ondeck NT, Bohl DD, Bovonratwet P, Anandasivam NS, Cui JJ, McLynn RP, Grauer JN. Predicting Adverse Outcomes After Total Hip Arthroplasty: A Comparison of Demographics, the American Society of Anesthesiologists class, the Modified Charlson Comorbidity Index, and the Modified Frailty Index. Journal Of The American Academy Of Orthopaedic Surgeons 2018, 26: 735-743. PMID: 30130353, DOI: 10.5435/jaaos-d-17-00009.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexTotal hip arthroplastyComorbidity indexAdverse outcomesAdverse eventsFrailty indexAnesthesiologists classTHA patientsHip arthroplastyModified Charlson Comorbidity IndexGeneral health complicationsModified Frailty IndexPerioperative adverse outcomesMinor adverse eventsExtended hospital staySevere adverse eventsHigh-level careComparison of demographicsAmerican SocietyDiscriminative abilityPatients ASAHospital stayPerioperative outcomesGreater discriminative abilityHealth complicationsDiscriminative Ability for Adverse Outcomes After Surgical Management of Hip Fractures
Ondeck NT, Bovonratwet P, Ibe IK, Bohl DD, McLynn RP, Cui JJ, Baumgaertner MR, Grauer JN. Discriminative Ability for Adverse Outcomes After Surgical Management of Hip Fractures. Journal Of Orthopaedic Trauma 2018, 32: 231-237. PMID: 29401098, DOI: 10.1097/bot.0000000000001140.Peer-Reviewed Original ResearchConceptsElixhauser comorbidity measuresCharlson Comorbidity IndexExtended hospital stayAdverse outcomesHip fractureComorbidity indexAdverse eventsSurgical managementLargest discriminative abilityHospital stayDiscriminative abilityDemographic factorsHospital adverse outcomesPrognostic Level IIIHip fracture surgeryMinor adverse eventsSevere adverse eventsHip fracture studiesNational Inpatient SampleOverall discriminative abilityAppropriate patient expectationsPostoperative complicationsFrailty indexFracture surgeryMedical managementDialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors
Ottesen TD, Zogg CK, Haynes MS, Malpani R, Bellamkonda KS, Grauer JN. Dialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors. The Journal Of Arthroplasty 2018, 33: 2827-2834. PMID: 29754981, DOI: 10.1016/j.arth.2018.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArthroplasty, Replacement, KneeComorbidityElective Surgical ProceduresFemaleHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePatient ReadmissionPostoperative ComplicationsQuality ImprovementRegression AnalysisRenal DialysisReoperationRetrospective StudiesRisk AssessmentConceptsTotal knee arthroplastyDialysis-dependent patientsAdverse eventsPatient demographicsDialysis patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseOverall healthRisk-adjusted logistic regressionElective total knee arthroplastyQuality Improvement Program databaseImprovement Program databaseMinor adverse eventsNational inpatient databaseSevere adverse eventsBone health statusNondialysis cohortNondialysis patientsPerioperative periodTKA patientsAdult patientsPreoperative riskComorbidity factorsInstitutional cohortMissing data treatments matter: an analysis of multiple imputation for anterior cervical discectomy and fusion procedures
Ondeck NT, Fu MC, Skrip LA, McLynn RP, Cui JJ, Basques BA, Albert TJ, Grauer JN. Missing data treatments matter: an analysis of multiple imputation for anterior cervical discectomy and fusion procedures. The Spine Journal 2018, 18: 2009-2017. PMID: 29649614, DOI: 10.1016/j.spinee.2018.04.001.Peer-Reviewed Original ResearchConceptsSevere adverse eventsNational Surgical Quality Improvement ProgramAnterior cervical discectomyAdverse eventsPreoperative anemiaPreoperative hypoalbuminemiaPreoperative albuminCervical discectomyHospital readmissionAdverse outcomesComplete case analysisSurgical Quality Improvement ProgramAdverse outcome variablesOne-level ACDFPreoperative laboratory valuesBody mass indexFusion proceduresMultiple imputationLogistic regression analysisQuality Improvement ProgramPreoperative hematocritPostoperative outcomesRetrospective reviewMass indexLaboratory values
2017
Predicting Postoperative Morbidity and Readmission for Revision Posterior Lumbar Fusion
Basques BA, Ibe I, Samuel AM, Lukasiewicz AM, Webb ML, Bohl DD, Grauer JN. Predicting Postoperative Morbidity and Readmission for Revision Posterior Lumbar Fusion. Clinical Spine Surgery A Spine Publication 2017, 30: e770-e775. PMID: 27280782, DOI: 10.1097/bsd.0000000000000391.Peer-Reviewed Original ResearchConceptsMinor adverse eventsSevere adverse eventsInsulin-dependent diabetesAdverse eventsPosterior lumbar fusionLumbar fusionRisk factorsASA classificationOperative timeSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMultivariate analysisBody mass index 25Quality Improvement Program databaseImprovement Program databaseRetrospective cohort studySpecific risk factorsAnesthesiologists classificationBMI 30Postoperative complicationsPostoperative morbidityCohort studyPatient characteristicsSicker patientsAdverse outcomesDiscriminative ability of commonly used indices to predict adverse outcomes after poster lumbar fusion: a comparison of demographics, ASA, the modified Charlson Comorbidity Index, and the modified Frailty Index
Ondeck NT, Bohl DD, Bovonratwet P, McLynn RP, Cui JJ, Shultz BN, Lukasiewicz AM, Grauer JN. Discriminative ability of commonly used indices to predict adverse outcomes after poster lumbar fusion: a comparison of demographics, ASA, the modified Charlson Comorbidity Index, and the modified Frailty Index. The Spine Journal 2017, 18: 44-52. PMID: 28578164, DOI: 10.1016/j.spinee.2017.05.028.Peer-Reviewed Original ResearchConceptsPosterior lumbar fusionPerioperative adverse outcomesNational Surgical Quality Improvement ProgramCharlson Comorbidity IndexComorbidity indexAdverse outcomesAdverse eventsFrailty indexLumbar fusionSurgeons National Surgical Quality Improvement ProgramElective posterior lumbar fusionAnesthesiologists Physical Status Classification SystemDiscriminative abilitySurgical Quality Improvement ProgramPhysical Status Classification SystemAdverse outcome variablesDemographic factorsInfectious adverse eventsOutcome variablesPatient comorbidity indexPredictive demographic factorsMinor adverse eventsSevere adverse eventsBody mass indexHigh-level careDifferences in Short-Term Outcomes Between Primary and Revision Anterior Cervical Discectomy and Fusion
Basques BA, Ondeck NT, Geiger EJ, Samuel AM, Lukasiewicz AM, Webb ML, Bohl DD, Massel DH, Mayo BC, Singh K, Grauer JN. Differences in Short-Term Outcomes Between Primary and Revision Anterior Cervical Discectomy and Fusion. Spine 2017, 42: 253-260. PMID: 28207667, DOI: 10.1097/brs.0000000000001718.Peer-Reviewed Original ResearchConceptsRevision anterior cervical discectomyAnterior cervical discectomySurgical site infectionACDF proceduresRevision proceduresAdverse eventsPostoperative lengthThromboembolic eventsCervical discectomySite infectionBlood transfusionOperative timeNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseQuality Improvement Program databaseOperating roomImprovement Program databaseMinor adverse eventsRetrospective cohort studySevere adverse eventsShort-term morbidityRisk of readmissionAverage operative timeShort-term outcomesMultiple adverse outcomes
2015
Predicting Short-term Morbidity in Patients Undergoing Posterior Spinal Fusion for Neuromuscular Scoliosis
Basques BA, Chung SH, Lukasiewicz AM, Webb ML, Samuel AM, Bohl DD, Smith BG, Grauer JN. Predicting Short-term Morbidity in Patients Undergoing Posterior Spinal Fusion for Neuromuscular Scoliosis. Spine 2015, 40: 1910-1917. PMID: 26261918, DOI: 10.1097/brs.0000000000001093.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionSevere adverse eventsShort-term morbidityNeuromuscular scoliosisAdverse eventsRisk factorsInfectious complicationsASA classificationSpinal fusionNational Surgical Quality Improvement Program Pediatric databaseSurgeons National Surgical Quality Improvement Program Pediatric databaseOnly independent risk factorPoor short-term outcomeShort-term adverse outcomesPrevious cardiac surgeryRetrospective cohort studyIndependent risk factorOnly risk factorShort-term outcomesBody mass indexNMS patientsAnesthesiologists classificationCohort studyPatient characteristicsCardiac surgeryMyelopathy Is Associated With Increased All-Cause Morbidity and Mortality Following Anterior Cervical Discectomy and Fusion
Lukasiewicz AM, Basques BA, Bohl DD, Webb ML, Samuel AM, Grauer JN. Myelopathy Is Associated With Increased All-Cause Morbidity and Mortality Following Anterior Cervical Discectomy and Fusion. Spine 2015, 40: 443-449. PMID: 25599286, DOI: 10.1097/brs.0000000000000785.Peer-Reviewed Original ResearchMeSH KeywordsAdultCervical VertebraeCohort StudiesDatabases, FactualDiskectomyFemaleHumansIntervertebral Disc DegenerationLength of StayLogistic ModelsMaleMiddle AgedOperative TimeQuality ImprovementRetrospective StudiesSocieties, MedicalSpinal Cord DiseasesSpinal DiseasesSpinal FusionSurvival RateTreatment OutcomeUnited StatesConceptsBaseline patient characteristicsAnterior cervical discectomyAdverse eventsACDF proceduresCervical discectomyCervical myelopathyPatient characteristicsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMultivariate analysisQuality Improvement Program databaseSerious adverse eventsCervical spine pathologyImprovement Program databaseSevere adverse eventsMultivariate logistic regressionCommon surgical procedureCause morbidityRetrospective cohortSurgical characteristicsPatient factorsHigh morbidityDifferent morbiditiesPatient counselingDiagnosis codesAdverse Events, Length of Stay, and Readmission After Surgery for Tibial Plateau Fractures
Basques BA, Webb ML, Bohl DD, Golinvaux NS, Grauer JN. Adverse Events, Length of Stay, and Readmission After Surgery for Tibial Plateau Fractures. Journal Of Orthopaedic Trauma 2015, 29: e121-e126. PMID: 25162975, DOI: 10.1097/bot.0000000000000231.Peer-Reviewed Original ResearchConceptsSevere adverse eventsTibial plateau fracturesASA classPlateau fracturesInfectious complicationsAdverse eventsPulmonary diseaseBicondylar fracturesExtended LOSMale sexSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseTibial plateau fracture patientsQuality Improvement Program databaseDependent functional statusPrognostic Level IIPercent of patientsImprovement Program databaseShort-term outcomesLength of stayAnesthesiologists classFracture patientsPatient characteristicsOpen reductionOperative time
2014
Morbidity and Readmission After Open Reduction and Internal Fixation of Ankle Fractures Are Associated With Preoperative Patient Characteristics
Basques BA, Miller CP, Golinvaux NS, Bohl DD, Grauer JN. Morbidity and Readmission After Open Reduction and Internal Fixation of Ankle Fractures Are Associated With Preoperative Patient Characteristics. Clinical Orthopaedics And Related Research® 2014, 473: 1133-1139. PMID: 25337977, PMCID: PMC4317425, DOI: 10.1007/s11999-014-4005-z.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAnkle FracturesDatabases, FactualDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleFracture Fixation, InternalHumansMaleMiddle AgedPatient ReadmissionPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsTreatment OutcomeYoung AdultConceptsDependent functional statusSevere adverse eventsAdverse eventsAnkle fracturesInfectious complicationsFunctional statusASA classificationBimalleolar fracturesPatient characteristicsDiabetes mellitusOpen reductionInternal fixationRisk factorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseShort-term adverse eventsQuality Improvement Program databaseInsulin-dependent diabetes mellitusNoninsulin-dependent diabetes mellitusACS-NSQIP registryAnkle fracture ORIFQuestions/PurposesThe purposePreoperative patient characteristicsCurrent Procedural Terminology codesImprovement Program databaseRisk Factors for Short-term Adverse Events and Readmission After Arthroscopic Meniscectomy
Basques BA, Gardner EC, Varthi AG, Fu MC, Bohl DD, Golinvaux NS, Grauer JN. Risk Factors for Short-term Adverse Events and Readmission After Arthroscopic Meniscectomy. The American Journal Of Sports Medicine 2014, 43: 169-175. PMID: 25294869, DOI: 10.1177/0363546514551923.Peer-Reviewed Original ResearchConceptsSevere adverse eventsAdverse eventsRisk factorsMedical comorbiditiesOlder patientsArthroscopic meniscectomySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseShort-term adverse eventsQuality Improvement Program databaseMultivariate logistic regression analysisOdds of readmissionPostoperative adverse eventsImprovement Program databaseHistory of smokingCase-control studyEvidence of osteoarthritisLevel of evidenceLogistic regression analysisComorbidity burdenPulmonary diseasePatient selectionPreoperative counselingCommon surgeryMean agePatient Factors Are Associated With Poor Short-term Outcomes After Posterior Fusion for Adolescent Idiopathic Scoliosis
Basques BA, Bohl DD, Golinvaux NS, Smith BG, Grauer JN. Patient Factors Are Associated With Poor Short-term Outcomes After Posterior Fusion for Adolescent Idiopathic Scoliosis. Clinical Orthopaedics And Related Research® 2014, 473: 286-294. PMID: 25201091, PMCID: PMC4390920, DOI: 10.1007/s11999-014-3911-4.Peer-Reviewed Original ResearchConceptsSevere adverse eventsLength of stayAdolescent idiopathic scoliosisAdverse eventsSurgical site infectionPerioperative morbiditySite infectionIdiopathic scoliosisSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramExtended LOSPoor short-term outcomeSurgical Quality Improvement ProgramInitial hospital stayResultsTwenty-seven patientsManagement of obesityIndividual adverse eventsShort-term outcomesTotal hospital costsMultivariate logistic regressionQuality Improvement ProgramHospital stayHospital readmissionNinety-fifth percentileOperative time