2024
P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsisP116. National trends and risk factors for new-onset depression following posterior lumbar fusion
Day W, Gouzoulis M, Zhu J, Seddio A, Fourman M, Grauer J. P116. National trends and risk factors for new-onset depression following posterior lumbar fusion. The Spine Journal 2024, 24: s119. DOI: 10.1016/j.spinee.2024.06.138.Peer-Reviewed Original ResearchNew-onset depressionPosterior lumbar fusionNational administrative claims databaseSingle-level posterior lumbar fusionRisk factorsDevelopment of new-onset depressionAdministrative claims databasePostoperative complicationsLumbar fusionNational trendsFactors associated with patientsClaims databaseAggregate patient dataAdult patientsTarget risk mitigation strategiesMultivariate logistic regressionPsychiatric risk factorsPotential risk factorsElixhauser Comorbidity IndexPercentage of patientsHigher oddsCase-controlAlcohol/drug abuseDiagnosis of tumorsLogistic regressionP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetesOutcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus
Salib A, Sanchez J, Huggins L, Seddio A, Dhodapkar M, Smith-Voudouris J, Norman M, Koumpouras F, Grauer J. Outcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus. Journal Of Shoulder And Elbow Surgery 2024 PMID: 39154846, DOI: 10.1016/j.jse.2024.07.008.Peer-Reviewed Original ResearchSystemic lupus erythematosus patientsSystemic lupus erythematosusTotal shoulder arthroplastyAdverse eventsImplant survivalLupus erythematosusMultivariate analysisShoulder arthroplastyIncreased oddsTotal shoulder arthroplasty patientsNon-SLE patientsMultivariate logistic regressionImmunomodulatory therapyPostoperative complicationsElixhauser Comorbidity IndexAdult patientsNinety-dayUnivariate analysisSurgical planningComorbidity indexPatient counselingGlenohumeral osteoarthritisPatientsComorbid conditionsOrthopedic-relatedRisk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNerveA Nationwide Analysis of Complications, Reoperations and Cost of Wide-Awake Flexor Tendon Repairs.
Kammien A, Rancu A, Kim S, Parikh N, Grauer J, Colen D. A Nationwide Analysis of Complications, Reoperations and Cost of Wide-Awake Flexor Tendon Repairs. Plastic & Reconstructive Surgery 2024 PMID: 39026384, DOI: 10.1097/prs.0000000000011651.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexWound complicationsTraditional anesthesiaEmergency department visitsYears of follow-upTendon repairAnalysis of complicationsRate of tendon ruptureNationwide cohort studyDepartment visitsWide-awake surgeryFlexor tendon repairConcomitant treatmentMatched cohortFollow-upZone II flexor tendon repairCohort studyMultivariate linear regressionAnesthesia techniquesComorbidity indexVascular injuryIntraoperative testingReoperationNerve repairPatientsTotal Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024 PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplastyAnkle fracture open reduction and internal fixation in patients with cerebral palsy
Dhodapkar M, Yang A, Jiang W, Halperin S, Frumberg D, Grauer J. Ankle fracture open reduction and internal fixation in patients with cerebral palsy. Developmental Medicine & Child Neurology 2024 PMID: 38773804, DOI: 10.1111/dmcn.15958.Peer-Reviewed Original ResearchAnkle fracture ORIFCerebral palsyAnkle fracturesElixhauser Comorbidity IndexInternational Classification of Diseases (ICD)-9 and ICD-10Increased oddsIsolated ankle fracturesEmergency department visitsClosed ankle fracturesInternal fixationProlonged lengthMultivariate logistic regressionAnkle fracture open reductionProlonged length of stayDepartment visitsLength of stayInternational ClassificationAdverse eventsStudy of adult patientsFracture open reductionMinor adverse eventsICD-10Logistic regressionORAnkleRobotic Versus Navigation Assisted Posterior Lumbar Fusion: A National Database Study.
Gouzoulis M, Seddio A, Winter A, Jabbouri S, Zhu J, Rubio D, Varthi A, Grauer J. Robotic Versus Navigation Assisted Posterior Lumbar Fusion: A National Database Study. Spine 2024 PMID: 38717329, DOI: 10.1097/brs.0000000000005032.Peer-Reviewed Original ResearchPosterior lumbar fusionLumbar fusionAdverse eventsLevel posterior lumbar fusionsCPT codesKaplan-Meier survival analysisRate of reoperationNavigation-assisted surgeryRobotic-assisted casesNavigation-assistedMinor adverse eventsPerioperative adverse eventsMultivariate logistic regressionICD-10 procedure codeRobotic cohortRobotic assistanceSpinal navigationReoperation rateAnterior fusionElixhauser Comorbidity IndexPearlDiver databaseNo significant differenceIncremental advantageAdverse outcomesComorbidity indexCefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion
Dhodapkar M, Jeong S, Halperin S, Rubio D, Li M, Grauer J. Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00082. PMCID: PMC11068128, DOI: 10.5435/jaaosglobal-d-24-00082.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSurgical site infectionElixhauser Comorbidity IndexLumbar fusionAntibiotic prophylaxisAdverse outcomesAntibiotic prophylaxis regimenAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisRevision ratePerioperative antibiotic prophylaxisPostoperative adverse outcomesPosterior lumbar fusion patientsMultivariate logistic regressionProphylaxis regimensProphylaxis regimenPatient ageSite infectionUnivariate analysisCefazolinComorbidity indexMultivariate analysisAntibiotic subgroupsTraumatic diagnosesThe Correlation of Surgical Setting With Perioperative Opioid Prescriptions for Wide-Awake Carpal Tunnel Release.
Kammien A, Hu K, Collar J, Rancu A, Zhao K, Grauer J, Colen D. The Correlation of Surgical Setting With Perioperative Opioid Prescriptions for Wide-Awake Carpal Tunnel Release. Hand 2024, 15589447241247247. PMID: 38654508, DOI: 10.1177/15589447241247247.Peer-Reviewed Original ResearchCarpal tunnel releasePerioperative opioid prescriptionOpioid prescriptionsAssociation of opioid prescriptionsSurgical settingOpioid utilizationPerioperative opioid utilizationMorphine milligram equivalentsAdministrative claims databaseOpioid dependence/abuseMilligram equivalentsPostoperative dataElixhauser Comorbidity IndexPain controlPreoperative dataBilateral surgeryTraditional anesthesiaBack/neck painMatched cohortOffice-based surgeryComorbidity indexMultivariate analysisOpioidSurgeryAnesthetic techniqueRisk of Adverse Events Following Total Knee Arthroplasty in Asthma Patients
Smith-Voudouris J, Rubin L, Grauer J. Risk of Adverse Events Following Total Knee Arthroplasty in Asthma Patients. Journal Of The American Academy Of Orthopaedic Surgeons 2024, 32: 543-549. PMID: 38657178, DOI: 10.5435/jaaos-d-23-01142.Peer-Reviewed Original ResearchAdverse eventsTotal knee arthroplastyElixhauser Comorbidity IndexOne-tenth of patientsAsthma patientsOdds of adverse eventsRisk of adverse eventsIncreasing severity of asthmaMultivariate logistic regressionInflammatory airway diseasesSeverity of asthmaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesAggregate adverse eventsAdult patientsNon-pulmonaryAirway diseaseComorbidity indexMultivariate analysisPatient factorsAsthma groupEmergency department visitsPatientsIncreased oddsEmergency department utilization after elbow arthroscopy
Day W, Gouzoulis M, Jayaram R, Grauer J. Emergency department utilization after elbow arthroscopy. JSES International 2024, 8: 910-914. PMID: 39035647, PMCID: PMC11258818, DOI: 10.1016/j.jseint.2024.03.015.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexEmergency departmentArthroscopy patientsED visitsElbow arthroscopyMethods Adult patientsAssociated with younger ageProportion of patientsAdministrative databasesFactors associated with ED visitsPostoperative care pathwaysNational administrative databasePostoperative courseAdult patientsPostoperative weekComorbidity indexMultivariate analysisPatientsSurgeryTechnical pearlsYounger ageEmergency department utilizationArthroscopyInsurance typeMonthsSurgical site infection following isolated lumbar discectomy increases odds of revision lumbar surgery within first 6 months, but not beyond
Kim L, Halperin S, Grauer J. Surgical site infection following isolated lumbar discectomy increases odds of revision lumbar surgery within first 6 months, but not beyond. The Spine Journal 2024, 24: 1459-1466. PMID: 38570035, DOI: 10.1016/j.spinee.2024.03.017.Peer-Reviewed Original ResearchSurgical site infectionRevision lumbar surgeryLumbar discectomyLumbar surgeryElixhauser Comorbidity IndexSite infectionFactors associated with surgical site infectionPreoperative diagnosis of infectionIncidence of secondary surgeryLumbar discectomy patientsDiagnosis of infectionMultivariate logistic regressionPreoperative diagnosisDiscectomy patientsPostoperative complicationsIndex surgeryPatient ageSecondary surgerySpinal surgeryIndependent predictorsAdult patientsLumbar fusionPerforming surgeryDiscectomyI&DFemale Patients Undergoing Latarjet Surgery Demonstrate Similar Two-Year Secondary Surgery Rates but Greater Risk of Emergency Department Visits Compared to a Matched Cohort of Male Patients
Gillinov S, Islam W, Modrak M, Mahatme R, Wilhelm C, McLaughlin W, Surucu S, Moran J, Lee M, Grauer J, Jimenez A. Female Patients Undergoing Latarjet Surgery Demonstrate Similar Two-Year Secondary Surgery Rates but Greater Risk of Emergency Department Visits Compared to a Matched Cohort of Male Patients. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2024 PMID: 38513877, DOI: 10.1016/j.arthro.2024.02.043.Peer-Reviewed Original ResearchSecondary surgery rateElixhauser Comorbidity Index scoreCohort of male patientsBody mass indexElixhauser Comorbidity IndexSurgery ratesRecurrent shoulder instabilityFemale patientsMale patientsLatarjet procedureFemale sexShoulder instabilityED visitsIncidence of secondary surgeryEmergency departmentAssociated with female sexInternational Classification of Diseases (ICD)-10 diagnosisNational administrative claims databaseKaplan-Meier analysisAssociated with OREvaluate sex-based differencesTreatment of recurrent shoulder instabilityPostoperative emergency departmentMultivariate logistic regressionAdministrative claims databaseTotal shoulder arthroplasty in patients with Factor V Leiden
Zehner K, Sanchez J, Dhodapkar M, Modrak M, Luo X, Grauer J. Total shoulder arthroplasty in patients with Factor V Leiden. Journal Of Shoulder And Elbow Surgery 2024 PMID: 38479723, DOI: 10.1016/j.jse.2024.01.041.Peer-Reviewed Original ResearchFactor V LeidenVenous thromboembolismAdverse eventsV LeidenTSA patientsRevision rateProphylactic agentFactor V Leiden patientsVTE prophylactic agentOdds ratioRisk of venous thromboembolismEffective treatment optionOdds of bleeding complicationsDeep vein thrombosisMultivariate logistic regressionEnd-stage glenohumeral osteoarthritisTotal shoulder arthroplastyInherited thrombophiliaBleeding complicationsElixhauser Comorbidity IndexLonger-term outcomesPulmonary embolismProthrombotic stateVein thrombosisAdult patientsOutcomes Following Total Hip Arthroplasty in Patients Who Have Von Willebrand Disease Depend on Postoperative Anticoagulation
Jiang W, Sanchez J, Dhodapkar M, Radford Z, Rubin L, Grauer J. Outcomes Following Total Hip Arthroplasty in Patients Who Have Von Willebrand Disease Depend on Postoperative Anticoagulation. The Journal Of Arthroplasty 2024, 39: 2088-2093. PMID: 38462141, DOI: 10.1016/j.arth.2024.03.004.Peer-Reviewed Original ResearchVon Willebrand diseaseVon Willebrand disease patientsRevision-free survivalVenous thromboembolismAdverse eventsOdds of venous thromboembolismTotal hip arthroplastyIncreased oddsDefects of von Willebrand factorCongenital bleeding disordersPatients to dateQualitative defects of von Willebrand factorPostoperative adverse eventsThrombotic adverse eventsMultivariate logistic regressionAutosomal dominant conditionVon Willebrand factorElixhauser Comorbidity IndexBleeding disordersPostoperative anticoagulationAdult patientsCompare bleedingPrescription patternsQualitative defectsWillebrand diseaseAnatomic vs. reverse total shoulder arthroplasty: usage trends and perioperative outcomes
Halperin S, Dhodapkar M, Kim L, Modrak M, Medvecky M, Donohue K, Grauer J. Anatomic vs. reverse total shoulder arthroplasty: usage trends and perioperative outcomes. Seminars In Arthroplasty JSES 2024, 34: 91-96. DOI: 10.1053/j.sart.2023.08.014.Peer-Reviewed Original ResearchTotal shoulder arthroplastyElixhauser Comorbidity IndexPerioperative outcomesAdverse eventsSurgeon volumeShoulder arthroplastyHigher Elixhauser comorbidity indexPerioperative adverse eventsSevere adverse eventsUrinary tract infectionCommon orthopaedic proceduresMatching of patientsPatient demographicsTract infectionsPearlDiver databaseMultivariable analysisOverall incidencePatient populationKidney infectionMerit further investigationOrthopedic proceduresGreater oddsRTSAIncreased percentagePatients