2024
P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsisP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetesOutcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus
Salib A, Sanchez J, Huggins L, Seddio A, Dhodapkar M, Smith-Voudouris J, Norman M, Koumpouras F, Grauer J. Outcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus. Journal Of Shoulder And Elbow Surgery 2024 PMID: 39154846, DOI: 10.1016/j.jse.2024.07.008.Peer-Reviewed Original ResearchSystemic lupus erythematosus patientsSystemic lupus erythematosusTotal shoulder arthroplastyAdverse eventsImplant survivalLupus erythematosusMultivariate analysisShoulder arthroplastyIncreased oddsTotal shoulder arthroplasty patientsNon-SLE patientsMultivariate logistic regressionImmunomodulatory therapyPostoperative complicationsElixhauser Comorbidity IndexAdult patientsNinety-dayUnivariate analysisSurgical planningComorbidity indexPatient counselingGlenohumeral osteoarthritisPatientsComorbid conditionsOrthopedic-relatedRisk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNervePrediction Models for Risk Assessment of Surgical Site Infection after Spinal Surgery: A Systematic Review
Lauinger A, Blake S, Fullenkamp A, Polites G, Grauer J, Arnold P. Prediction Models for Risk Assessment of Surgical Site Infection after Spinal Surgery: A Systematic Review. North American Spine Society Journal (NASSJ) 2024, 100518. DOI: 10.1016/j.xnsj.2024.100518.Peer-Reviewed Original ResearchSurgical site infectionPreoperative risk modelSpinal surgerySite infectionAdverse eventsAssessment of surgical site infectionACS NSQIP surgical risk calculatorPostoperative surgical site infectionNSQIP surgical risk calculatorRate of adverse eventsSpine surgery patientsRisk of adverse eventsStratify patient riskSurgical risk calculatorField of spine surgeryClinical prediction toolSpine surgeryRisk modelSurgery patientsSurgeryAddressing factorsPatient riskClinical utilitySystematic reviewUnique susceptibilityTotal Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024 PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplastyAnkle fracture open reduction and internal fixation in patients with cerebral palsy
Dhodapkar M, Yang A, Jiang W, Halperin S, Frumberg D, Grauer J. Ankle fracture open reduction and internal fixation in patients with cerebral palsy. Developmental Medicine & Child Neurology 2024 PMID: 38773804, DOI: 10.1111/dmcn.15958.Peer-Reviewed Original ResearchAnkle fracture ORIFCerebral palsyAnkle fracturesElixhauser Comorbidity IndexInternational Classification of Diseases (ICD)-9 and ICD-10Increased oddsIsolated ankle fracturesEmergency department visitsClosed ankle fracturesInternal fixationProlonged lengthMultivariate logistic regressionAnkle fracture open reductionProlonged length of stayDepartment visitsLength of stayInternational ClassificationAdverse eventsStudy of adult patientsFracture open reductionMinor adverse eventsICD-10Logistic regressionORAnkleIncreased Risk of 90-Day Complications in Patients With Fibromyalgia Undergoing Total Shoulder Arthroplasty
Sanchez J, Rancu A, Diatta F, Jonnalagadda A, Dhodapkar M, Knoedler L, Kauke-Navarro M, Grauer J. Increased Risk of 90-Day Complications in Patients With Fibromyalgia Undergoing Total Shoulder Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e24.00102. PMID: 38722914, PMCID: PMC11081627, DOI: 10.5435/jaaosglobal-d-24-00102.Peer-Reviewed Original ResearchConceptsRevision-free survivalDay of surgeryAdverse eventsTSA patientsIncreased riskMultivariate analysisOdds ratioIncreased risk of adverse eventsUrinary tract infectionLog-rank testRisk of adverse eventsSurgical site infectionSevere adverse eventsEffective treatment optionAcute kidney injuryDeep vein thrombosisMinor adverse eventsNon-fibromyalgia patientsEnd-stage glenohumeral osteoarthritisAssociation of fibromyalgiaIncreased odds ratioTotal shoulder arthroplastyShoulder infectionPulmonary embolismTract infectionsRobotic Versus Navigation Assisted Posterior Lumbar Fusion: A National Database Study.
Gouzoulis M, Seddio A, Winter A, Jabbouri S, Zhu J, Rubio D, Varthi A, Grauer J. Robotic Versus Navigation Assisted Posterior Lumbar Fusion: A National Database Study. Spine 2024 PMID: 38717329, DOI: 10.1097/brs.0000000000005032.Peer-Reviewed Original ResearchPosterior lumbar fusionLumbar fusionAdverse eventsLevel posterior lumbar fusionsCPT codesKaplan-Meier survival analysisRate of reoperationNavigation-assisted surgeryRobotic-assisted casesNavigation-assistedMinor adverse eventsPerioperative adverse eventsMultivariate logistic regressionICD-10 procedure codeRobotic cohortRobotic assistanceSpinal navigationReoperation rateAnterior fusionElixhauser Comorbidity IndexPearlDiver databaseNo significant differenceIncremental advantageAdverse outcomesComorbidity indexRisk of Adverse Events Following Total Knee Arthroplasty in Asthma Patients
Smith-Voudouris J, Rubin L, Grauer J. Risk of Adverse Events Following Total Knee Arthroplasty in Asthma Patients. Journal Of The American Academy Of Orthopaedic Surgeons 2024, 32: 543-549. PMID: 38657178, DOI: 10.5435/jaaos-d-23-01142.Peer-Reviewed Original ResearchAdverse eventsTotal knee arthroplastyElixhauser Comorbidity IndexOne-tenth of patientsAsthma patientsOdds of adverse eventsRisk of adverse eventsIncreasing severity of asthmaMultivariate logistic regressionInflammatory airway diseasesSeverity of asthmaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesAggregate adverse eventsAdult patientsNon-pulmonaryAirway diseaseComorbidity indexMultivariate analysisPatient factorsAsthma groupEmergency department visitsPatientsIncreased oddsTotal shoulder arthroplasty in patients with Factor V Leiden
Zehner K, Sanchez J, Dhodapkar M, Modrak M, Luo X, Grauer J. Total shoulder arthroplasty in patients with Factor V Leiden. Journal Of Shoulder And Elbow Surgery 2024 PMID: 38479723, DOI: 10.1016/j.jse.2024.01.041.Peer-Reviewed Original ResearchFactor V LeidenVenous thromboembolismAdverse eventsV LeidenTSA patientsRevision rateProphylactic agentFactor V Leiden patientsVTE prophylactic agentOdds ratioRisk of venous thromboembolismEffective treatment optionOdds of bleeding complicationsDeep vein thrombosisMultivariate logistic regressionEnd-stage glenohumeral osteoarthritisTotal shoulder arthroplastyInherited thrombophiliaBleeding complicationsElixhauser Comorbidity IndexLonger-term outcomesPulmonary embolismProthrombotic stateVein thrombosisAdult patientsOutcomes Following Total Hip Arthroplasty in Patients Who Have Von Willebrand Disease Depend on Postoperative Anticoagulation
Jiang W, Sanchez J, Dhodapkar M, Radford Z, Rubin L, Grauer J. Outcomes Following Total Hip Arthroplasty in Patients Who Have Von Willebrand Disease Depend on Postoperative Anticoagulation. The Journal Of Arthroplasty 2024, 39: 2088-2093. PMID: 38462141, DOI: 10.1016/j.arth.2024.03.004.Peer-Reviewed Original ResearchVon Willebrand diseaseVon Willebrand disease patientsRevision-free survivalVenous thromboembolismAdverse eventsOdds of venous thromboembolismTotal hip arthroplastyIncreased oddsDefects of von Willebrand factorCongenital bleeding disordersPatients to dateQualitative defects of von Willebrand factorPostoperative adverse eventsThrombotic adverse eventsMultivariate logistic regressionAutosomal dominant conditionVon Willebrand factorElixhauser Comorbidity IndexBleeding disordersPostoperative anticoagulationAdult patientsCompare bleedingPrescription patternsQualitative defectsWillebrand diseaseAnatomic vs. reverse total shoulder arthroplasty: usage trends and perioperative outcomes
Halperin S, Dhodapkar M, Kim L, Modrak M, Medvecky M, Donohue K, Grauer J. Anatomic vs. reverse total shoulder arthroplasty: usage trends and perioperative outcomes. Seminars In Arthroplasty JSES 2024, 34: 91-96. DOI: 10.1053/j.sart.2023.08.014.Peer-Reviewed Original ResearchTotal shoulder arthroplastyElixhauser Comorbidity IndexPerioperative outcomesAdverse eventsSurgeon volumeShoulder arthroplastyHigher Elixhauser comorbidity indexPerioperative adverse eventsSevere adverse eventsUrinary tract infectionCommon orthopaedic proceduresMatching of patientsPatient demographicsTract infectionsPearlDiver databaseMultivariable analysisOverall incidencePatient populationKidney infectionMerit further investigationOrthopedic proceduresGreater oddsRTSAIncreased percentagePatientsFemoral Head Core Decompressions: Characterization of Subsequent Conversion to Total Hip Arthroplasty and Related Complications
Jiang W, Sanchez J, Dhodapkar M, Li M, Wiznia D, Grauer J. Femoral Head Core Decompressions: Characterization of Subsequent Conversion to Total Hip Arthroplasty and Related Complications. JAAOS Global Research And Reviews 2024, 8: e24.00024. PMID: 38437034, PMCID: PMC10906578, DOI: 10.5435/jaaosglobal-d-24-00024.Peer-Reviewed Original ResearchAnatomic and reverse total shoulder arthroplasty: Variables affecting 90-day overall reimbursement
Halperin S, Dhodapkar M, Modrak M, Donohue K, Medvecky M, Grauer J. Anatomic and reverse total shoulder arthroplasty: Variables affecting 90-day overall reimbursement. Seminars In Arthroplasty JSES 2024 DOI: 10.1053/j.sart.2024.02.007.Peer-Reviewed Original ResearchAnatomic total shoulder arthroplastyReverse total shoulder arthroplastyTotal shoulder arthroplastyTotal shoulder arthroplasty patientsPostoperative eventsShoulder arthroplastyPatient demographicsOverall reimbursementSurgery typeAdverse eventsMale sexAssociated with reimbursementMultivariate linear regressionOncological diagnosisEmergency department visitsPatientsOrthopedic proceduresEffective procedureAdministrative databasesHospital readmissionInsurance typeSurgeryReduce healthcare expendituresDepartment visitsIncreased frequencyAdverse Events After Isolated Posterior Cruciate Ligament Reconstruction: A National Database Study
Kammien A, Price R, McLaughlin W, Park N, Richter D, Schenck R, Grauer J, Medvecky M. Adverse Events After Isolated Posterior Cruciate Ligament Reconstruction: A National Database Study. Orthopaedic Journal Of Sports Medicine 2024, 12: 23259671231222123. PMID: 38249782, PMCID: PMC10798085, DOI: 10.1177/23259671231222123.Peer-Reviewed Original ResearchRate of adverse eventsSurgical site infectionIsolated PCL reconstructionAdverse eventsPCL reconstructionPulmonary embolismSite infectionCompartment syndromePosterior cruciate ligamentVariable rates of complicationsOdds ratioVascular eventsOptimal managementIsolated posterior cruciate ligament reconstructionConcomitant ligament surgeryEmergency departmentNational cohortDeep vein thrombosesRate of complicationsElixhauser Comorbidity Index scoreDay of surgeryDeep vein thrombosisCalculate odds ratiosPosterior cruciate ligament reconstructionComorbidity Index score
2023
Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Kaszuba S, Rubin L, Grauer J. Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 32: 309-315. PMID: 38165956, DOI: 10.5435/jaaos-d-23-00783.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyUrinary tract infectionPostoperative eventsCystic fibrosisPerioperative outcomesAdverse eventsTract infectionsPleural effusionKnee arthroplastyControl subjectsRevision rateAcute kidney injuryElixhauser Comorbidity IndexRisk of surgeryMultivariable logistic regressionComorbidity indexKidney injuryPerioperative complicationsRespiratory failureTKA patientsCardiac eventsPearlDiver databaseImplant survivalTotal hipNinety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease
Dhodapkar M, Halperin S, Saifi C, Whang P, Grauer J, Varthi A. Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease. The Spine Journal 2023, 24: 807-811. PMID: 38081460, DOI: 10.1016/j.spinee.2023.11.025.Peer-Reviewed Original ResearchPosterior lumbar interbody fusionSingle-level posterior lumbar interbody fusionSickle cell diseaseElixhauser Comorbidity IndexAdverse eventsPostoperative outcomesInterbody fusionOdds ratioCell diseaseDays adverse eventsMinor adverse eventsPostoperative adverse eventsPerioperative adverse eventsSevere adverse eventsCohort of patientsED visit ratesEmergency department visitsMultivariable logistic regressionNational administrative databaseRetrospective database studyLumbar interbody fusionSingle level posteriorComorbidity indexPLIF patientsAdult patients