2022
Clinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future
Ahmad Y, Madhavan M, Baron S, Forrest J, Borger M, Leipsic J, Cavalcante J, Wang D, McCarthy P, Szerlip M, Kapadia S, Makkar R, Mack M, Leon M, Cohen D. Clinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future. Structural Heart 2022, 7: 100102. PMID: 37275317, PMCID: PMC10236801, DOI: 10.1016/j.shj.2022.100102.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementBicuspid aortic valve diseaseSurgical aortic valve replacementAortic valve replacementAortic valve diseaseValve replacementClinical researchValve diseaseValvular heart diseaseDesign of RCTsProcedural therapiesProspective registryHeart diseaseExclusion criteriaRisk scorePatientsRCTsDiseaseCardiovascular communityMultidisciplinary workshopSelection biasTrialsInternational expertsPotential studiesRegistryImaging, Treatment Options, Patient Selection, and Outcome Considerations for Patients With Bicuspid Aortic Valve Disease
Ahmad Y, Agarwal V, Williams M, Wang D, Reardon M, Cavalcante J, Makkar R, Forrest J. Imaging, Treatment Options, Patient Selection, and Outcome Considerations for Patients With Bicuspid Aortic Valve Disease. Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 1: 100506. PMID: 39132366, PMCID: PMC11307905, DOI: 10.1016/j.jscai.2022.100506.Peer-Reviewed Original ResearchAortic valve replacementTranscatheter aortic valve replacementBicuspid aortic valve diseaseAortic valve diseaseValve replacementValve diseaseBAV diseaseSevere symptomatic aortic stenosisSurgical aortic valve replacementPivotal randomized trialsAortic valve surgerySymptomatic aortic stenosisRandomized clinical trialsValve surgeryHeart teamAortic stenosisSurgical riskPatient selectionRandomized trialsBicuspid valveSurgical approachTreatment optionsClinical trialsPatientsDisease
2015
Comparison of Inhospital Outcomes of Surgical Aortic Valve Replacement in Hospitals With and Without Availability of a Transcatheter Aortic Valve Implantation Program (from a Nationally Representative Database)
Singh V, Badheka AO, Patel SV, Patel NJ, Thakkar B, Patel N, Arora S, Patel N, Patel A, Savani C, Ghatak A, Panaich SS, Jhamnani S, Deshmukh A, Chothani A, Sonani R, Patel A, Bhatt P, Dave A, Bhimani R, Mohamad T, Grines C, Cleman M, Forrest JK, Mangi A. Comparison of Inhospital Outcomes of Surgical Aortic Valve Replacement in Hospitals With and Without Availability of a Transcatheter Aortic Valve Implantation Program (from a Nationally Representative Database). The American Journal Of Cardiology 2015, 116: 1229-1236. PMID: 26297512, DOI: 10.1016/j.amjcard.2015.07.039.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveBicuspid Aortic Valve DiseaseCardiac Care FacilitiesDatabases, FactualFemaleHeart Defects, CongenitalHeart Valve DiseasesHospital MortalityHospitalizationHumansMaleMiddle AgedPropensity ScoreTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve implantation (TAVI) programCo-morbidity scoreAortic valve replacementTAVI programNationwide Inpatient SampleTAVI groupComplication rateInhospital outcomesValve replacementConventional surgical aortic valve replacementCharlson co-morbidity scoreClinical Modification procedure codesLower inhospital mortalityAortic valve diseaseCost of hospitalizationImplantation programYears of ageInhospital mortalitySAVR proceduresHospital stayValve diseaseNinth RevisionMean agePatient populationTrends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease
Badheka AO, Singh V, Patel NJ, Arora S, Patel N, Thakkar B, Jhamnani S, Pant S, Chothani A, Macon C, Panaich SS, Patel J, Manvar S, Savani C, Bhatt P, Panchal V, Patel N, Patel A, Patel D, Lahewala S, Deshmukh A, Mohamad T, Mangi AA, Cleman M, Forrest JK. Trends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease. The American Journal Of Cardiology 2015, 116: 132-141. PMID: 25983278, DOI: 10.1016/j.amjcard.2015.03.053.Peer-Reviewed Original ResearchConceptsAortic valve diseaseCost of hospitalizationInhospital mortalityHeart failureValve diseaseHigh burdenEconomic burdenFrequent coexisting conditionsOverall inhospital mortalitySubgroup of patientsValvular heart diseaseInnovative therapeutic optionsNationwide Inpatient SamplePrincipal discharge diagnosisNumber of hospitalizationsTrend of hospitalizationsPublic health systemRenal failureAortic stenosisDischarge diagnosisNinth RevisionTherapeutic optionsPatient populationInpatient SampleCoexisting conditions