Impact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis
Ito S, Laham R, Nkomo V, Forrest J, Reardon M, Little S, Mumtaz M, Gada H, Bajwa T, Langholz D, Heiser J, Chawla A, Jenson B, Attizanni G, Markowitz A, Huang J, Oh J. Impact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis. Open Heart 2023, 10: e002297. PMID: 37173100, PMCID: PMC10186477, DOI: 10.1136/openhrt-2023-002297.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementAortic stenosisSymptomatic patientsValve replacementKansas City Cardiomyopathy Questionnaire overall summary scoreEvolut Low Risk trialSurgical aortic valve replacementLow-risk trialsLow-risk patientsOverall summary scoreRate of deathQuality of lifeDisabling strokeEchocardiographic evidenceIsolated AVRHaemodynamic profileClinical outcomesHaemodynamic outcomesRisk trialsClinical trialsCalcium volumeSummary scoresPatientsCore laboratory measurements