2006
Shark rectal gland vasoactive intestinal peptide receptor: cloning, functional expression, and regulation of CFTR chloride channels
Bewley MS, Pena JT, Plesch FN, Decker SE, Weber GJ, Forrest JN. Shark rectal gland vasoactive intestinal peptide receptor: cloning, functional expression, and regulation of CFTR chloride channels. AJP Regulatory Integrative And Comparative Physiology 2006, 291: r1157-r1164. PMID: 16728467, DOI: 10.1152/ajpregu.00078.2006.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsCell Cycle ProteinsChloridesCloning, MolecularConserved SequenceCystic Fibrosis Transmembrane Conductance RegulatorDogfishEndodeoxyribonucleasesGene Expression RegulationIn Vitro TechniquesMaleMolecular Sequence DataOocytesPatch-Clamp TechniquesPhylogenyReceptors, Vasoactive Intestinal PeptideReverse Transcriptase Polymerase Chain ReactionSalt GlandVasoactive Intestinal PeptideXenopus laevisConceptsShark rectal glandCFTR chloride channelRectal glandVasoactive intestinal peptideChloride channelsN-glycosylation sitesG protein-coupled receptorsUnique G protein-coupled receptorProtein-coupled receptorsChloride conductanceCysteine residuesNH2 terminusChloride secretionFunctional expressionGrowth hormone-releasing hormoneCFTR mRNADogfish sharkAmino acidsPeptide histidine isoleucine amideRelative potencyXenopus oocytesHormone-releasing hormoneHistidine isoleucine amideQuantitative PCRMicroeq x
1991
Cl- secretion by cultured shark rectal gland cells. I. Transepithelial transport
Valentich JD, Forrest JN. Cl- secretion by cultured shark rectal gland cells. I. Transepithelial transport. American Journal Of Physiology 1991, 260: c813-c823. PMID: 2018113, DOI: 10.1152/ajpcell.1991.260.4.c813.Peer-Reviewed Original ResearchConceptsVasoactive intestinal peptideCl- secretory epitheliaPrimary monolayer culture systemCyclic monophosphate (cAMP) accumulationShark rectal gland (SRG) epithelial cellsIntestinal peptidePotent secretagogueGland epithelial cellsAutocrine mediatorMonophosphate accumulationCultured shark rectal gland cellsEpithelial cells