2016
Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors
Kleiman N, Maini B, Reardon M, Conte J, Katz S, Rajagopal V, Kauten J, Hartman A, McKay R, Hagberg R, Huang J, Popma J, Adams D, Ad N, Aharonian V, Anderson W, Applegate R, Bafi A, Bajwa T, Bakhos M, Ball S, Batra S, Beohar N, Brachinsky W, Brinster D, Brown J, Byrne J, Byrne T, Casale A, Caskey M, Chawla A, Cohen H, Coselli J, Costa M, Cheatham J, Chetcuti S, Crestanello J, Davis T, Michael Deeb G, Diez J, Dauerman H, Elefteriades J, Fail P, Feinberg E, Fontana G, Forrest J, Galloway A, Giacomini J, Gleason T, Guadiani V, Harrison J, Hebeler R, Heimansohn D, Heiser J, Heller L, Henry S, Hermiller J, Hockmuth D, Hughes G, Joye J, Kafi A, Kar B, Khabbaz K, Kipperman R, Kliger C, Kon N, Lamelas J, Lee J, Leya F, Londono J, Macheers S, Mangi A, de Marchena E, Markowitz A, Matthews R, Merhi W, Mumtaz M, O’Hair D, Petrossian G, Pfeffer T, Raybuck B, Resar J, Robbins M, Robbins R, Robinson N, Ring M, Salerno T, Schreiber T, Schmoker J, Sharma S, Siwek L, Skelding K, Slater J, Starnes V, Stoler R, Subramanian V, Tadros P, Thompson C, Waksman R, Watson D, Yakubov S, Zhao D, Zorn G. Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors. Circulation Cardiovascular Interventions 2016, 9: e003551. PMID: 27601429, DOI: 10.1161/circinterventions.115.003551.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBalloon ValvuloplastyBioprosthesisCalcinosisCardiac Pacing, ArtificialClinical Trials as TopicFemaleHeart Valve ProsthesisHumansIncidenceIntracranial EmbolismKaplan-Meier EstimateMaleProportional Hazards ModelsRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementEarly strokePrior coronary artery bypass surgeryHealth Stroke Scale scoreSelf-expanding CoreValve bioprosthesisCoronary artery bypass surgerySmaller body surface areaLower body mass indexContinued Access StudySevere aortic calcificationStroke Scale scoreTransient ischemic attackArtery bypass surgeryPeripheral vascular diseasePredictors of strokeBody mass indexBody surface areaIdentification of predictorsCoreValve bioprosthesisIschemic attackPrior strokeBypass surgeryAortic calcification
2015
Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFR
Koyner JL, Coca SG, Thiessen-Philbrook H, Patel UD, Shlipak MG, Garg AX, Parikh CR, Consortium T, Raman J, Jeevanandam V, Akhter S, Devarajan P, Bennett M, Ma Q, Griffiths R, Edelstein C, Passik C, Nagy J, Swaminathan M, Chu M, Goldbach M, Guo L, McKenzie N, Myers M, Novick R, Quantz M, Schumann V, Webster L, Zappitelli M, Palijan A, Dewar M, Darr U, Hashim S, Elefteriades J, Geirsson A, Garwood S, Kemp R, Butrymowicz I. Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFR. American Journal Of Kidney Diseases 2015, 66: 1006-1014. PMID: 26386737, PMCID: PMC4658239, DOI: 10.1053/j.ajkd.2015.07.027.Peer-Reviewed Original ResearchConceptsAcute kidney injurySevere acute kidney injuryPost-operative dialysisBaseline eGFRKidney injuryInterleukin-18Urinary biomarkersDevelopment of AKIAKI Network stage 1Clinical acute kidney injuryPerioperative acute kidney injuryKidney injury molecule-1Liver-type fatty acid binding proteinBaseline kidney functionImpact of PreoperativeSerum creatinine levelsHours of surgeryInjury molecule-1Prospective cohort studyGlomerular filtration rateNumber of patientsPerformance of biomarkersFatty acid binding proteinAdjusted RRsPreoperative eGFR
2007
What Is the Optimal Management of Late-Presenting Survivors of Acute Type A Aortic Dissection?
Davies RR, Coe MP, Mandapati D, Gallo A, Botta DM, Elefteriades JA, Coady MA. What Is the Optimal Management of Late-Presenting Survivors of Acute Type A Aortic Dissection? The Annals Of Thoracic Surgery 2007, 83: 1593-1602. PMID: 17462364, DOI: 10.1016/j.athoracsur.2006.12.018.Peer-Reviewed Original ResearchConceptsLong-term survivalOperative repairAortic dissectionGroup AAcute Type A Aortic DissectionType A Aortic DissectionImproved long-term survivalOptimal managementExcellent long-term resultsA Aortic DissectionInitial medical managementCongestive heart failureCoronary artery diseaseOnset of symptomsLong-term resultsImmediate operative repairAcute typeSurgical emergencySymptom onsetArtery diseaseHeart failurePulmonary diseaseMedical managementSingle institutionGroup B
2000
Effect of left ventricular volume on results of coronary artery bypass grafting
Kim R, Ugurlu B, Tereb D, Wackers F, Tellides G, Elefteriades J. Effect of left ventricular volume on results of coronary artery bypass grafting. The American Journal Of Cardiology 2000, 86: 1261-1264. PMID: 11090805, DOI: 10.1016/s0002-9149(00)01216-9.Peer-Reviewed Original ResearchConceptsCoronary artery bypassArtery bypassSignificant left ventricular dilationLeft ventricular dilationLV chamber sizeLV ejection fractionMedium-term survivalSurgical revascularizationAngina symptomsEjection fractionIschemic cardiomyopathyLV dilationVentricular dilationVentricular sizeVentricular volumePatientsSignificant reductionBypassChamber sizeDilationRevascularizationCardiomyopathySymptoms
1999
DEVELOPING SURGICAL INTERVENTION CRITERIA FOR THORACIC AORTIC ANEURYSMS
Coady M, Rizzo J, Elefteriades J. DEVELOPING SURGICAL INTERVENTION CRITERIA FOR THORACIC AORTIC ANEURYSMS. Cardiology Clinics 1999, 17: 827-839. PMID: 10589349, DOI: 10.1016/s0733-8651(05)70118-1.Peer-Reviewed Original ResearchConceptsSurgical interventionAcute ascending aortic dissectionAscending aortic dissectionConcomitant aortic insufficiencyIntervention criteriaLarger patient numbersAppropriate clinical careThoracic aortic aneurysmSize criteriaSurgical intervention criteriaOverall physical conditionAortic insufficiencyAdverse eventsAortic dissectionPatient ageAortic sizeOrgan compressionPatient enrollmentPatient numbersAortic aneurysmThoracic aortaSymptomatic stateClinical careClinical experienceLife expectancyPATHOLOGIC VARIANTS OF THORACIC AORTIC DISSECTIONS Penetrating Atherosclerotic Ulcers and Intramural Hematomas
Coady M, Rizzo J, Elefteriades J. PATHOLOGIC VARIANTS OF THORACIC AORTIC DISSECTIONS Penetrating Atherosclerotic Ulcers and Intramural Hematomas. Cardiology Clinics 1999, 17: 637-657. PMID: 10589337, DOI: 10.1016/s0733-8651(05)70106-5.Peer-Reviewed Original ResearchConceptsClassic aortic dissectionAcute aortic pathologyIntramural hematomaAortic dissectionAortic lumenAtherosclerotic ulcerAortic lesionsIMH patientsAortic pathologyClassic dissectionRupture rateType B aortic dissectionTypical aortic dissectionB aortic dissectionDistinct clinical entityThoracic aortic dissectionTypical patient profileMore superficial locationHigher rupture rateBranch-vessel compromiseLarger aortasMinimal arteriosclerosisTypical dissectionIschemic manifestationsThoracoabdominal aortaFailure to Improve Left Ventricular Function After Coronary Revascularization for Ischemic Cardiomyopathy Is Not Associated With Worse Outcome
Samady H, Elefteriades J, Abbott B, Mattera J, McPherson C, Wackers F. Failure to Improve Left Ventricular Function After Coronary Revascularization for Ischemic Cardiomyopathy Is Not Associated With Worse Outcome. Circulation 1999, 100: 1298-1304. PMID: 10491374, DOI: 10.1161/01.cir.100.12.1298.Peer-Reviewed Original ResearchConceptsVentricular functionIschemic cardiomyopathyGroup AHeart failure scoreLeft ventricular functionIschemic LV dysfunctionPoor patient outcomesB. Group ALack of improvementBaseline LVEFEffective revascularizationImproved LVEFCoronary revascularizationLV dysfunctionConsecutive patientsIntraoperative variablesPostoperative improvementCardiac deathLV functionPoor outcomeViable myocardiumLVEF assessmentIschemic myocardiumPatient outcomesWorse outcomesSurgical intervention criteria for thoracic aortic aneurysms: a study of growth rates and complications
Coady M, Rizzo J, Hammond G, Kopf G, Elefteriades J. Surgical intervention criteria for thoracic aortic aneurysms: a study of growth rates and complications. The Annals Of Thoracic Surgery 1999, 67: 1922-1926. PMID: 10391339, DOI: 10.1016/s0003-4975(99)00431-2.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic aneurysmDevastating complicationAortic growth rateComplications of ruptureIncidence of dissectionTime of complicationsRisk of dissectionMultivariable regression analysisMedian sizeSurgical intervention criteriaTime of dissectionAcute dissectionElective resectionPerioperative complicationsInitial presentationSurgical interventionRisk factorsThoracic aortaAneurysm sizeComplicationsTime of ruptureYale University SchoolLower mortalityAneurysms
1998
Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it?
Coady M, Rizzo J, Hammond G, Pierce J, Kopf G, Elefteriades J. Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it? Journal Of Vascular Surgery 1998, 27: 1006-1016. PMID: 9652462, DOI: 10.1016/s0741-5214(98)70003-5.Peer-Reviewed Original ResearchConceptsAortic dissectionOptimal treatmentThoracic aortaNatural historyType AType B aortic dissectionB aortic dissectionClassic aortic dissectionLarger aortic diametersAortic ulcerAtherosclerotic ulcerAortic ruptureClinical featuresInitial diagnosisInitial presentationIntraoperative findingsRetrospective reviewSurgical managementAortic diameterRadiologic signsTomographic scanPathology reportsUlcersPatientsAortaShould Angiographically Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo Coronary Artery Bypass Grafting?
Mehta I, Weinberg J, Jones M, Tellides G, Kopf G, Shaw R, Zaret B, Elefteriades J. Should Angiographically Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo Coronary Artery Bypass Grafting? The Annals Of Thoracic Surgery 1998, 65: 17-23. PMID: 9456088, DOI: 10.1016/s0003-4975(97)01192-2.Peer-Reviewed Original ResearchConceptsSaphenous vein graftsVein graftsRedo CABGDisease-free graftsNR groupRedo Coronary Artery Bypass GraftingR groupCoronary Artery Bypass GraftingRedo coronary artery bypassGood late survivalArtery Bypass GraftingCoronary artery bypassLate myocardial infarctionFirst CABGRecurrent anginaRedo revascularizationArtery bypassBypass GraftingOperative mortalitySurgical mortalityAngiographic evaluationCardiac hospitalizationConsecutive patientsNew stenosisRandomized study
1997
Results of Coronary Artery Bypass Grafting by a Single Surgeon Patients With Left Ventricular Ejection Fractions ≤30%
Elefteriades J, Morales D, Gradel C, Tollis G, Levi E, Zaret B. Results of Coronary Artery Bypass Grafting by a Single Surgeon Patients With Left Ventricular Ejection Fractions ≤30%. The American Journal Of Cardiology 1997, 79: 1573-1578. PMID: 9202343, DOI: 10.1016/s0002-9149(97)00201-4.Peer-Reviewed Original ResearchConceptsAdvanced LV dysfunctionInternal mammary arteryCoronary artery diseaseEjection fractionLV dysfunctionMammary arteryArtery diseaseCongestive heart failure classSevere left ventricular dysfunctionCoronary Artery Bypass GraftingBetter long-term survivalHeart failure classSingle surgeon's patientsArtery Bypass GraftingCoronary artery bypassHigh operative riskLeft ventricular dysfunctionSevere ventricular arrhythmiasLV ejection fractionVentricular ejection fractionUse of CABGLong-term survivalQuality of lifeAngina classArtery bypassWhat is the appropriate size criterion for resection of thoracic aortic aneurysms?
Coady M, Rizzo J, Hammond G, Mandapati D, Darr U, Kopf G, Elefteriades J. What is the appropriate size criterion for resection of thoracic aortic aneurysms? Journal Of Thoracic And Cardiovascular Surgery 1997, 113: 476-491. PMID: 9081092, DOI: 10.1016/s0022-5223(97)70360-x.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic aneurysmIncidence of dissectionTime of complicationsMultivariable regression analysisMedian sizeAppropriate size criterionTime of dissectionAcute dissectionElective resectionPerioperative complicationsDevastating complicationOverall survivalAortic dissectionInitial presentationElective operationsSurgical interventionRisk factorsThoracic aortaAneurysm sizeTime of rupturePatientsYale University SchoolAneurysmsLower mortality
1993
Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state
Elefteriades J, Tolis G, Levi E, Mills L, Zaret B. Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state. Journal Of The American College Of Cardiology 1993, 22: 1411-1417. PMID: 8227799, DOI: 10.1016/0735-1097(93)90551-b.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisAdultAgedAged, 80 and overCause of DeathCoronary Artery BypassDefibrillators, ImplantableFemaleFollow-Up StudiesHeart DiseasesHospital MortalityHumansIntra-Aortic Balloon PumpingMaleMammary ArteriesMiddle AgedPrognosisQuality of LifeSeverity of Illness IndexStroke VolumeSurvival RateVentricular Function, LeftConceptsCoronary Artery Bypass GraftingArtery Bypass GraftingCoronary artery bypassSevere left ventricular dysfunctionLeft ventricular ejection fractionInternal mammary arteryLeft ventricular dysfunctionVentricular ejection fractionEjection fractionArtery bypassVentricular dysfunctionBypass GraftingMammary arteryMortality rateCanadian Cardiovascular Society angina classCongestive heart failure classGood medium-term survivalAdvanced ischemic cardiomyopathyAdvanced ventricular dysfunctionHeart failure classImproved ejection fractionHospital mortality rateCongestive heart failureIntraaortic balloon pumpSignificant ventricular arrhythmiasLinear left ventricular aneurysmectomy: Modern imaging studies reveal improved morphology and function
Elefteriades J, Solomon L, Salazar A, Batsford W, Baldwin J, Kopf G. Linear left ventricular aneurysmectomy: Modern imaging studies reveal improved morphology and function. The Annals Of Thoracic Surgery 1993, 56: 242-252. PMID: 8347005, DOI: 10.1016/0003-4975(93)91154-f.Peer-Reviewed Original ResearchConceptsCoronary artery bypassIntraoperative transesophageal echocardiographyArtery bypassVentricular aneurysmectomyTransesophageal echocardiographyConcomitant coronary artery bypassCongestive heart failure classFrank congestive heart failureHeart failure classActuarial survival rateHospital mortality rateCongestive heart failureWall motion scoreMean wall motion scoreModern imaging studiesMagnetic resonance imagingAcquisition scanningAnginal classValve replacementConsecutive patientsEjection fractionHeart failureVentricular functionEndocardial resectionVentricular morphology
1992
Strategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience
GEHA A, ELEFTERIADES J, HSU J, BIBLO L, HOCH D, BATSFORD W, ROSENFELD L, CARLSON M, JOHNSON N, WALDO A. Strategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience. Annals Of Surgery 1992, 216: 309-317. PMID: 1417180, PMCID: PMC1242614, DOI: 10.1097/00000658-199209000-00010.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorSubendocardial resectionVentricular tachycardiaSurgical treatmentLV aneurysmSudden deathThirty-day mortality rateSevere LV dysfunctionCongestive heart failureRecurrent ventricular tachycardiaSignificant myocardial ischemiaLong-term survivorsMalignant ventricular arrhythmiasMalignant ventricular tachyarrhythmiasCent of survivorsImplantable cardioverter defibrillatorLong-term survivalActuarial survivalAntiarrhythmic medicationsLate deathsComparable patientsLV dysfunctionConsecutive patientsHeart failureVentricular arrhythmiasTransesophageal echocardiographic evaluation of aortic valve integrity with antegrade crystalloid cardioplegic solution used as an imaging agent
Rafferty T, Durkin M, Elefteriades J, O’Connor T. Transesophageal echocardiographic evaluation of aortic valve integrity with antegrade crystalloid cardioplegic solution used as an imaging agent. Journal Of Thoracic And Cardiovascular Surgery 1992, 104: 637-641. PMID: 1513154, DOI: 10.1016/s0022-5223(19)34729-4.Peer-Reviewed Original ResearchConceptsCrystalloid cardioplegic solutionCardioplegic solutionValve dysfunctionValve integrityEchocardiographic contrast agentsImaging agentVentricular dimensional changesAortic regurgitationEchocardiographic evaluationLeft atriumCardiac dimensionsIntravascular injectionSolution administrationPatientsDysfunctionContrast agentsAgentsEchocardiographyRegurgitationAtriumAdministrationTransesophageal color flow Doppler imaging for aortic insufficiency in patients having cardiac operations
Rafferty T, Durkin M, Sittig D, Ezekowitz M, LaMantia K, Davis E, Elefteriades J. Transesophageal color flow Doppler imaging for aortic insufficiency in patients having cardiac operations. Journal Of Thoracic And Cardiovascular Surgery 1992, 104: 521-525. PMID: 1495319, DOI: 10.1016/s0022-5223(19)34815-9.Peer-Reviewed Original ResearchConceptsAortic insufficiencyCardiac operationsLeft ventricular outflow tract dimensionColor flow Doppler assessmentColor flow Doppler findingsVentricular outflow tract dimensionColor flow DopplerLeft ventricular cavityDoppler findingsDoppler assessmentFlow DopplerAngiographic gradeVentricular cavityPatientsRegurgitant jetInsufficiencyTract dimensionsProximal widthAortographyEsophagusLong-term experience with descending aortic dissection: The complication-specific approach
Elefteriades J, Hartleroad J, Gusberg R, Salazar A, Black H, Kopf G, Baldwin J, Hammond G. Long-term experience with descending aortic dissection: The complication-specific approach. The Annals Of Thoracic Surgery 1992, 53: 11-21. PMID: 1728218, DOI: 10.1016/0003-4975(92)90752-p.Peer-Reviewed Original ResearchConceptsComplication-specific approachAortic dissectionActuarial survivalGraft replacementComplications of dissectionLower intercostal arteriesLeft subclavian arteryLong-term resultsUncomplicated dissectionLimb ischemiaPostoperative studiesSubclavian arteryFalse lumenSurgical managementIntercostal arteriesRadiographic findingsComplicated dissectionFenestration procedurePatientsSaccular aneurysmLong-term experienceAortaWhole groupDissectionFenestration
1990
Fenestration Revisited: A Safe and Effective Procedure for Descending Aortic Dissection
Elefteriades J, Hammond G, Gusberg R, Kopf G, Baldwin J. Fenestration Revisited: A Safe and Effective Procedure for Descending Aortic Dissection. JAMA Surgery 1990, 125: 786-790. PMID: 2346378, DOI: 10.1001/archsurg.1990.01410180112018.Peer-Reviewed Original ResearchEvolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias
Elefteriades J, Biblo L, Batsford W, Rosenfeld L, Henthorn R, Carlson M, Waldo A, Hsu J, Geha A. Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias. The Annals Of Thoracic Surgery 1990, 49: 94-100. PMID: 2297279, DOI: 10.1016/0003-4975(90)90362-a.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorResection groupThirty-day mortalityCoronary artery bypassMalignant ventricular tachyarrhythmiasIntractable ventricular arrhythmiasImplantable cardioverter defibrillatorAICD placementArtery bypassSurgical treatmentEndocardial resectionVentricular arrhythmiasVentricular tachyarrhythmiasAntiarrhythmic agentsSudden deathCardioverter defibrillatorResectionMortality figuresPatientsEffective interventionsGreatest overall benefitSurvivalGroupOverall benefitValuable alternative