2007
Gene Expression Signature in Peripheral Blood Detects Thoracic Aortic Aneurysm
Wang Y, Barbacioru CC, Shiffman D, Balasubramanian S, Iakoubova O, Tranquilli M, Albornoz G, Blake J, Mehmet NN, Ngadimo D, Poulter K, Chan F, Samaha RR, Elefteriades JA. Gene Expression Signature in Peripheral Blood Detects Thoracic Aortic Aneurysm. PLOS ONE 2007, 2: e1050. PMID: 17940614, PMCID: PMC2002514, DOI: 10.1371/journal.pone.0001050.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, ThoracicCase-Control StudiesCluster AnalysisFalse Positive ReactionsGene ExpressionGene Expression ProfilingGene Expression RegulationGenome, HumanHumansOligonucleotide Array Sequence AnalysisReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityTranscription, GeneticConceptsPeripheral blood cellsGene expression signaturesAortic aneurysmPeripheral bloodTAA patientsExpression signaturesBlood cellsBlood-based gene expression testAdverse clinical outcomesElective surgical repairThoracic aortic aneurysmPeripheral blood samplesPotential diagnostic markerPotential signature genesClassifier genesGene expression testDistinct gene expression signaturesSurgical repairClinical outcomesReal-time PCRBlood samplesRisk individualsTherapeutic interventionsDisease statusHigh mortality
1998
Procedures for Estimating Growth Rates in Thoracic Aortic Aneurysms
Rizzo J, Coady M, Elefteriades J. Procedures for Estimating Growth Rates in Thoracic Aortic Aneurysms. Journal Of Clinical Epidemiology 1998, 51: 747-754. PMID: 9731923, DOI: 10.1016/s0895-4356(98)00050-x.Peer-Reviewed Original ResearchConceptsTAA growth ratesStatistical problemsStatistical methodsEstimation procedureTAA growthConventional approachesMore reliable resultsInstrumental variable estimationVariable estimationMeasurement errorRate estimatesPrecise estimatesEstimationMeasured growth rateReliable estimatesEstimatesReliable resultsProblemConventional methodsApproachLethal medical conditionError
1993
The relationship between “Normal” transesophageal color-flow doppler-defined tricuspid regurgitation and thermodilution right ventricular ejection fraction measurements
Rafferty T, Durkin M, Hines R, Elefteriades J, O'Connor T. The relationship between “Normal” transesophageal color-flow doppler-defined tricuspid regurgitation and thermodilution right ventricular ejection fraction measurements. Journal Of Cardiothoracic And Vascular Anesthesia 1993, 7: 167-174. PMID: 8477021, DOI: 10.1016/1053-0770(93)90211-3.Peer-Reviewed Original ResearchConceptsTricuspid regurgitationEjection fractionRight ventricular ejection fraction measurementsThermodilution right ventricular ejection fractionRight atrial pressure waveformTricuspid regurgitation jet areaRight ventricular ejection fractionVentricular ejection fraction measurementsRight ventricular functionVentricular ejection fractionJet areaEjection fraction measurementsRevascularization patientsChest closureCardiopulmonary bypassVentricular functionAtrial areaEndotracheal intubationTricuspid valveRegurgitation indexRegurgitationWaveform abnormalitiesExcursion ratioPressure waveformRegression analysis
1992
Thermodilution right ventricular ejection fraction measurement reproducibility—A study in patients undergoing coronary artery bypass graft surgery
RAFFERTY T, DURKIN M, HINES R, ELEFTERIADES J, HARRIS S, O'CONNOR T. Thermodilution right ventricular ejection fraction measurement reproducibility—A study in patients undergoing coronary artery bypass graft surgery. Critical Care Medicine 1992, 20: 1524-1528. PMID: 1424694, DOI: 10.1097/00003246-199211000-00008.Peer-Reviewed Original ResearchConceptsRight ventricular systolic performanceVentricular systolic performanceHeart rateCardiac indexSystolic performanceRight ventricular end-diastolic volume indexRight ventricular ejection fraction measurementsCoronary artery bypass graft surgeryVentricular end-diastolic volume indexCoronary artery bypass graft patientsArtery bypass graft surgeryEnd-diastolic volume indexRight ventricular ejection fractionVentricular ejection fraction measurementsBypass graft surgeryBypass graft patientsVentricular ejection fractionRight atrial areaEjection fraction measurementsGraft patientsGraft surgeryDiastolic diameterEjection fractionAtrial areaProspective study