2007
Patient satisfaction in specialized versus nonspecialized adult sickle cell care centers: the PiSCES study.
Aisiku IP, Penberthy LT, Smith WR, Bovbjerg VE, McClish DK, Levenson JL, Roberts JD, Roseff SD. Patient satisfaction in specialized versus nonspecialized adult sickle cell care centers: the PiSCES study. Journal Of The National Medical Association 2007, 99: 886-90. PMID: 17722665, PMCID: PMC2574305.Peer-Reviewed Original ResearchConceptsNonspecialized centersPatient satisfactionSpecialized centersSCD careSCD patientsCare centerInterpersonal mannerSatisfaction scoresHighest mean satisfaction scoreSickle cell disease patientsProspective cohort studyGeneral satisfactionPatient satisfaction surveyMean satisfaction scoreQuality of careHigher satisfaction scoresSatisfaction surveySCD specialistsCohort studySignificant group differencesPotential confoundersDisease patientsAmbulatory carePatientsPractice style
1998
Phase Ib trial of bryostatin 1 in patients with refractory malignancies.
Grant S, Roberts J, Poplin E, Tombes MB, Kyle B, Welch D, Carr M, Bear HD. Phase Ib trial of bryostatin 1 in patients with refractory malignancies. Clinical Cancer Research 1998, 4: 611-8. PMID: 9533528.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic AgentsBryostatinsCohort StudiesCytotoxicity, ImmunologicDrug Administration ScheduleFemaleHumansImmunophenotypingInfusions, IntravenousInterleukin-2LactonesLymphocyte ActivationLymphocytesLymphomaMacrolidesMaleMetabolic Clearance RateMiddle AgedNeoplasmsPatient SelectionPlatelet AggregationProtein Kinase CConceptsPhase Ib trialIb trialCohort 3Lymphokine-activated killer cell activityBryostatin 1Bryostatin-1 administrationObjective clinical responsesKiller cell activityLiver function testsSubset of patientsBryostatin 1 treatmentSignificant posttreatment increasePKC activitySplit courseClinical responseFirst doseLiver metastasesNonhematological malignanciesRefractory malignanciesFunction testsPatient cohortCohort 1Interleukin-2Immunophenotypic profileTransient elevation