2011
Association between polymorphisms in catechol‐O‐methyltransferase (COMT) and cocaine‐induced paranoia in European‐American and African‐American populations
Ittiwut R, Listman JB, Ittiwut C, Cubells JF, Weiss RD, Brady K, Oslin D, Farrer LA, Kranzler HR, Gelernter J. Association between polymorphisms in catechol‐O‐methyltransferase (COMT) and cocaine‐induced paranoia in European‐American and African‐American populations. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2011, 156: 651-660. PMID: 21656904, PMCID: PMC3864552, DOI: 10.1002/ajmg.b.31205.Peer-Reviewed Original Research
1993
Assignment of the norepinephrine transporter protein (NET1) locusto chromosome 16
Gelernter J, Kruger S, Pakstis A, Pacholczyk T, Sparkes R, Kidd K, Amara S. Assignment of the norepinephrine transporter protein (NET1) locusto chromosome 16. Genomics 1993, 18: 690-692. PMID: 7905857, DOI: 10.1016/s0888-7543(05)80375-1.Peer-Reviewed Original ResearchMeSH KeywordsCarrier ProteinsChromosome MappingChromosomes, Human, Pair 16Deoxyribonucleases, Type II Site-SpecificDNA, ComplementaryGenetic LinkageGenetic MarkersHumansNorepinephrineNorepinephrine Plasma Membrane Transport ProteinsPolymorphism, Restriction Fragment LengthRestriction MappingSymportersConceptsNorepinephrine transporter proteinSomatic cell hybrid panelCell hybrid panelHybrid panelHP locusCEPH familiesLarge multigenerational familyTransporter proteinsLinkage analysisChromosome 16Provisional assignmentLinkage dataLociMultigenerational familiesGenetic polymorphismsSite of actionPreliminary assignmentNet1FamilyProteinRFLPSitesPolymorphismPCRLocalization
1988
Schizophrenia: Instability in Norepinephrine, Serotonin, and γ-Aminobutyric Acid Systems
Gelernter J, van Kammen D. Schizophrenia: Instability in Norepinephrine, Serotonin, and γ-Aminobutyric Acid Systems. International Review Of Neurobiology 1988, 29: 309-347. PMID: 3042667, DOI: 10.1016/s0074-7742(08)60091-4.Peer-Reviewed Original ResearchConceptsGABA systemΓ-aminobutyric acid (GABA) systemPathophysiology of schizophreniaClinical instabilitySymptomatic periodClinical syndromeDA dysregulationNeurotransmitter systemsSystem disordersState-dependent changesClinical pathologyConflicting dataSchizophrenia researchSchizophreniaDopamineGenetic vulnerabilitySchizophrenic individualsMost evidenceNorepinephrineSerotoninNE systemDisordersEvidenceRelapsePathophysiology