2014
Clinical features of methamphetamine‐induced paranoia and preliminary genetic association with DBH‐1021C→T in a Thai treatment cohort
Kalayasiri R, Verachai V, Gelernter J, Mutirangura A, Malison RT. Clinical features of methamphetamine‐induced paranoia and preliminary genetic association with DBH‐1021C→T in a Thai treatment cohort. Addiction 2014, 109: 965-976. PMID: 24521142, PMCID: PMC4018411, DOI: 10.1111/add.12512.Peer-Reviewed Original ResearchConceptsDopamine β-hydroxylaseMethamphetamine-dependent individualsAssociated clinical variablesGenetic polymorphismsΒ-hydroxylaseLogistic regression analysisSubstance abuse treatment centersHigh-activity genotypesSemi-Structured AssessmentAntisocial personality disorderCT carriersCent of individualsClinical featuresClinical presentationCigarette smokingClinical variablesRetrospective analysisTreatment centersDrug dependenceActivity genotypeMethamphetamine useMethamphetamine dependencePersonality disorderRegression analysisGenetic association
2006
Apolipoprotein E ε4 Allele Is Unrelated to Cognitive or Functional Decline in Alzheimer’s Disease: Retrospective and Prospective Analysis
Kleiman T, Zdanys K, Black B, Rightmer T, Grey M, Garman K, MacAvoy M, Gelernter J, van Dyck C. Apolipoprotein E ε4 Allele Is Unrelated to Cognitive or Functional Decline in Alzheimer’s Disease: Retrospective and Prospective Analysis. Dementia And Geriatric Cognitive Disorders 2006, 22: 73-82. PMID: 16699282, DOI: 10.1159/000093316.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseFunctional declineProspective analysisAD patientsEpsilon4 doseMultiple subsequent time pointsApolipoprotein E (APOE) ε4 alleleGenotype groupsApolipoprotein E epsilon4 alleleDuration of symptomsAD patient samplesGenetic risk factorsSubsequent time pointsTests of cognitionRisk factorsAPOE epsilon4Disease onsetDisease progressionEpsilon4 alleleFunctional impairmentRetrospective analysisΕ4 alleleDaily functionPatient samplesFunctional measures