2023
Cannabis positivity rates in 17 emergency departments across the United States with varying degrees of marijuana legalization
Tolan N, Krasowski M, Mathias P, Wiencek J, Babic N, Chai P, Chambliss A, Choucair I, Demetriou C, Erickson T, Feldhammer M, French D, Hayes B, Kang P, El-Khoury J, Knezevic C, Monte A, Nerenz R, Okorodudu A, Roper S, Saitman A, Thiriveedhi V, Uljon S, Vest A, Woodworth A, Yu M, Melanson S. Cannabis positivity rates in 17 emergency departments across the United States with varying degrees of marijuana legalization. Clinical Toxicology 2023, 61: 248-259. PMID: 37129223, PMCID: PMC10793079, DOI: 10.1080/15563650.2023.2177552.Peer-Reviewed Original Research
2021
Determination of 97.5th and 99th percentile upper reference limits for heart-type fatty acid-binding protein (H-FABP) in a US population
Vera MA, Koch CD, Kavsak PA, El-Khoury JM. Determination of 97.5th and 99th percentile upper reference limits for heart-type fatty acid-binding protein (H-FABP) in a US population. Clinica Chimica Acta 2021, 523: 397-401. PMID: 34666029, DOI: 10.1016/j.cca.2021.10.011.Peer-Reviewed Original ResearchConceptsHeart-type fatty acid-binding proteinUpper reference limitPercentile upper reference limitClinical utilityReference limitsAcute kidney injuryHeart-type fatty acidAcute coronary syndromeAACC Universal Sample BankFatty acid-binding proteinH-FABP concentrationHealthy U.S.Coronary syndromeFinal sample populationKidney injuryAssay cutoffHealthy donorsAcid-binding proteinUS populationImmunoturbidimetric assayPotential biomarkersClinical sensitivityMyocardial tissueSerum samplesLow molecular weight proteinsThe 2021 PhD Board-Certified Clinical Chemist Compensation Survey
Patel K, El-Khoury JM, Kataria Y, Wheeler S, Hackenmueller S. The 2021 PhD Board-Certified Clinical Chemist Compensation Survey. The Journal Of Applied Laboratory Medicine 2021, 6: 1655-1659. PMID: 34427677, DOI: 10.1093/jalm/jfab105.Peer-Reviewed Original ResearchMeSH KeywordsCertificationHumansProspective StudiesSalaries and Fringe BenefitsSurveys and QuestionnairesUnited StatesConceptsAcademic medical centerLongitudinal Assessment of SARS-CoV-2 Anti-Nucleocapsid and anti-Spike-1-RBD Antibody Testing Following PCR-Detected SARS-CoV-2 Infection
El-Khoury JM, Schulz WL, Durant TJS. Longitudinal Assessment of SARS-CoV-2 Anti-Nucleocapsid and anti-Spike-1-RBD Antibody Testing Following PCR-Detected SARS-CoV-2 Infection. The Journal Of Applied Laboratory Medicine 2021, 6: jfab030-. PMID: 33822964, PMCID: PMC8083453, DOI: 10.1093/jalm/jfab030.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionDays post-PCR positivitySARS-CoV-2-positive cohortRBD antibodiesAnti-SARSSerologic assaysSARS-CoV-2 serologic assaysDiagnostic sensitivityElecsys Anti-SARSCoV-2 SResidual clinical samplesAntibody testingRemote historyCoV-2S1-RBDUS populationLongitudinal assessmentInfection statusInfectionDiagnostic aidCohortTime pointsDiscrepant resultsClinical samplesPositivity
2020
First- and Second-Trimester Reference Intervals for Thyroid Function Testing in a US Population
Bunch DR, Firmender K, Harb R, El-Khoury JM. First- and Second-Trimester Reference Intervals for Thyroid Function Testing in a US Population. American Journal Of Clinical Pathology 2020, 155: 776-780. PMID: 33210132, DOI: 10.1093/ajcp/aqaa165.Peer-Reviewed Original ResearchConceptsThyroid-stimulating hormoneTrimester-specific reference intervalsThyroid function testsMIU/LPmol/LReference intervalsFunction testsUS populationSecond trimester prenatal screeningRoche analyzersThyroid function testingNegative screening resultsSpecific reference intervalsRoche Modular E170Singleton pregnanciesThyroglobulin antibodiesThyroid dysfunctionFirst trimesterSecond trimesterAdverse outcomesFunction testingFree thyroxineTotal triiodothyronineTotal thyroxineModular E170Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes.
Mansour SG, Liu C, Jia Y, Reese PP, Hall IE, El-Achkar TM, LaFavers KA, Obeid W, Rosenberg AZ, Daneshpajouhnejad P, Doshi MD, Akalin E, Bromberg JS, Harhay MN, Mohan S, Muthukumar T, Schröppel B, Singh P, El-Khoury JM, Weng FL, Thiessen-Philbrook HR, Parikh CR. Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes. Transplantation 2020, 105: 876-885. PMID: 32769629, PMCID: PMC8805736, DOI: 10.1097/tp.0000000000003299.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnimalsBiomarkersCells, CulturedDelayed Graft FunctionFemaleGlomerular Filtration RateGraft SurvivalHistocompatibility Antigens Class IIHumansKidneyKidney TransplantationMacrophagesMaleMiceMiddle AgedOsteopontinProspective StudiesRisk AssessmentRisk FactorsTime FactorsTissue DonorsUnited StatesUromodulinConceptsGraft failureGraft functionGraft outcomePrimary outcomeMajor histocompatibilityDeath-censored graft failureDeceased donor kidney transplantationCause graft failureImproved graft survivalRecipient graft outcomesKidney graft outcomeGlomerular filtration rateDeceased donor kidneysTime of procurementGraft survivalKidney transplantationDirection of associationDeceased donorsFiltration rateKidney qualityLower riskExtensive injuryDonor urineSimilar associationMouse macrophagesThe 2018 AACC/SYCL PhD Clinical Chemist Compensation Survey
Bunch DR, El-Khoury JM, Colby J, Colon-Franco J, Hackenmueller SA, Olson KN, Cotten SW, Kampfrath T, Chittiprol S, Suh-Lailam B, French D, Isbell TS, Nerenz RD, Parnas ML, Tolan NV. The 2018 AACC/SYCL PhD Clinical Chemist Compensation Survey. The Journal Of Applied Laboratory Medicine 2020, 5: 377-387. PMID: 32445390, DOI: 10.1093/jalm/jfaa001.Peer-Reviewed Original Research