2024
Biomarkers vs Machines: The Race to Predict Acute Kidney Injury
Ghazi L, Farhat K, Hoenig M, Durant T, El-Khoury J. Biomarkers vs Machines: The Race to Predict Acute Kidney Injury. Clinical Chemistry 2024, 70: 805-819. PMID: 38299927, DOI: 10.1093/clinchem/hvad217.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAcute kidney injuryEarly diagnosisInsulin-like growth factor-binding protein 7Prediction of acute kidney injuryGrowth factor-binding protein 7Detect acute kidney injuryNeutrophil gelatinase-associated lipocalinAcute kidney injury detectionClinical practiceIrreversible kidney damageClinical outcome studiesImminent AKISerum creatinineKidney injuryInjury markersPediatric populationCystatin CTissue inhibitorHospitalized patientsClinical useKidney damageRegulatory approvalProtein 7BiomarkersOutcome studies
2021
The ALT upper reference interval debate: Blame it on the alcohol
Vera MA, Koch CD, Liapakis A, Lim JK, El-Khoury JM. The ALT upper reference interval debate: Blame it on the alcohol. Clinica Chimica Acta 2021, 526: 62-65. PMID: 34973184, DOI: 10.1016/j.cca.2021.12.026.Peer-Reviewed Original ResearchConceptsUpper reference limitAdult groupHigher upper reference limitLiver diseasePediatric groupPediatric GastroenterologyPediatric populationClinical guidelinesALT valuesAmerican CollegeDerivation studyAge groupsReference limitsNorth American SocietyAmerican SocietyClinical laboratoriesRoche Cobas 8000GastroenterologyLaboratory expertsWomenCobas 8000MenGroupVariable inclusionIndividuals