2022
Post-infantile Giant Cell Hepatitis: A Literature Review and Meta-analysis
Jiao J, Zhang X. Post-infantile Giant Cell Hepatitis: A Literature Review and Meta-analysis. Journal Of Clinical And Translational Pathology 2022, 2: 100-107. PMID: 37092012, PMCID: PMC10117396, DOI: 10.14218/jctp.2022.00016.Peer-Reviewed Original ResearchPost-infantile giant cell hepatitisDisease entityEtiological factorsAdditional etiological factorsGiant cell hepatitisRare disease entityVariable clinical courseGamma-glutamyl transferaseDiffuse distribution patternInterface hepatitisLobular inflammationPortal inflammationUncommon etiologyClinical courseEtiological distributionAutoimmune disordersPoor outcomeHistological featuresWorse outcomesTotal bilirubinMultifactorial etiologyBetter outcomesPatientsViral infectionMeta-Analysis
2021
Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis
Sanchez J, Jiao J, Kwan S, Veillon L, Warmoes M, Tan L, Odewole M, Rich N, Wei P, Lorenzi P, Singal A, Beretta L. Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis. Cancer Prevention Research 2021, 14: canprevres.0612.2021. PMID: 34253566, PMCID: PMC8546639, DOI: 10.1158/1940-6207.capr-20-0612.Peer-Reviewed Original ResearchConceptsLogistic regression analysisHCC exosomesCirrhotic patientsEarly detectionHepatocellular carcinomaCandidate biomarkersTumor developmentNoninvasive diagnostic biomarkersRegression analysisHCC surveillanceLipid profileEndocannabinoid signalingHCC diagnosisNovel biomarkersLipid classesDiagnostic biomarkersPlasma exosomesLipidomic profilesGlycerophospholipid metabolismHCCPatientsBiomarkersUntargeted lipidomicsCarcinomaDifferential effectsSomatic Mutations in Circulating Cell-Free DNA and Risk for Hepatocellular Carcinoma in Hispanics
Jiao J, Sanchez J, Thompson E, Mao X, McCormick J, Fisher-Hoch S, Futreal P, Zhang J, Beretta L. Somatic Mutations in Circulating Cell-Free DNA and Risk for Hepatocellular Carcinoma in Hispanics. International Journal Of Molecular Sciences 2021, 22: 7411. PMID: 34299031, PMCID: PMC8304329, DOI: 10.3390/ijms22147411.Peer-Reviewed Original ResearchConceptsAdvanced liver fibrosisCell-free DNAHigher cfDNA concentrationsHepatocellular carcinomaLiver fibrosisCfDNA concentrationHCC patientsOverall survivalAdvanced fibrosisHCC risk predictionShorter overall survivalMajor risk factorNon-invasive markerPlasma cell-free DNADetectable mutationsSomatic mutationsCirculating Cell-Free DNARisk factorsHCC developmentCancer-associated genesDeath outcomesFibrosisPatientsNonsynonymous mutationsRisk predictionLiver Involvement by Perforated Peptic Ulcer: A Systematic Review
Jiao J, Zhang L. Liver Involvement by Perforated Peptic Ulcer: A Systematic Review. Journal Of Clinical And Translational Pathology 2021, 1: 2-8. PMID: 34927172, PMCID: PMC8681229, DOI: 10.14218/jctp.2021.00007.Peer-Reviewed Original ResearchLiver involvementGastric ulcerDuodenal ulcerPeptic ulcerNon-steroidal anti-inflammatory drugsPerforated Peptic UlcerPerforated duodenal ulcerPeptic ulcer diseaseAnti-inflammatory drugsCareful histologic examinationLiver penetrationGastric remnantLarge ulcersMedian ageFemale patientsMale patientsUlcer diseaseClinicopathological correlationFemale ratioPathological featuresHistologic examinationUlcersPatientsPubMed databaseSystematic review
2018
Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors
Jiao J, Watt G, Stevenson H, Calderone T, Fisher‐Hoch S, Ye Y, Wu X, Vierling J, Beretta L. Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors. Hepatology Communications 2018, 2: 718-731. PMID: 29881823, PMCID: PMC5983165, DOI: 10.1002/hep4.1187.Peer-Reviewed Original ResearchEvidence of HCCHepatitis C virusReverse transcriptase mutationsCell-free DNAHepatocellular carcinomaMale patientsTranscriptase mutationsLong-term imaging surveillancePlasma cell-free DNAFrequent genetic alterationsAlcoholic cirrhosisCancer Genome AtlasImaging surveillanceT promoter mutationClinical parametersMale sexPoor prognosisC virusRisk factorsSimilar prevalenceEarly biomarkersFamily historyHigh prevalenceCirrhosisPatients
2017
Prevalence of Aflatoxin-associated TP53R249S mutation in Hepatocellular Carcinoma in Hispanics in South Texas
Jiao J, Niu W, Wang Y, Baggerly K, Ye Y, Wu X, Davenport D, Almeda J, Betancourt-Garcia M, Forse R, Stevenson H, Watt G, McCormick J, Fisher-Hoch S, Beretta L. Prevalence of Aflatoxin-associated TP53R249S mutation in Hepatocellular Carcinoma in Hispanics in South Texas. Cancer Prevention Research 2017, 11: 103-112. PMID: 29089331, PMCID: PMC5811406, DOI: 10.1158/1940-6207.capr-17-0235.Peer-Reviewed Original ResearchConceptsAdvanced fibrosisHepatocellular carcinomaCell-free DNAHCC patientsHispanic subjectsShorter overall survivalPlasma cell-free DNAAsian HCC patientsOverall survivalWorse prognosisAflatoxin exposureHigh incidenceCirrhosisHCC tumorsPromising biomarkerDietary exposureFibrosisYounger agePatientsDroplet digital PCRHispanicsSomatic mutationsFamily membersUpstream regulatorSubjects