2023
Postinfantile Giant Cell Hepatitis in Native and Allograft Livers: A Multi-Institutional Clinicopathologic Study of 70 Cases
Jiao J, Chezar K, Zhang X, Wang D, Cao W, Bindu C, Chen W, Neto A, Henn P, Riahi I, Wang H, Papke D, Zhao L, Xue Y, Liao X, Zhang X. Postinfantile Giant Cell Hepatitis in Native and Allograft Livers: A Multi-Institutional Clinicopathologic Study of 70 Cases. Modern Pathology 2023, 36: 100298. PMID: 37544363, DOI: 10.1016/j.modpat.2023.100298.Peer-Reviewed Original ResearchConceptsPostinfantile giant cell hepatitisAutoimmune liver diseaseGiant cell hepatitisAlkaline phosphatase levelsClinical outcomesPhosphatase levelsLiver diseaseMulti-institutional retrospective studyAssociated with better survivalAssociated with poor survivalClinicopathological characteristics of patientsAdverse prognostic factorAssociated with autoimmune liver diseasesGiant cellsVariable clinical outcomesFollow-up resultsCharacteristics of patientsDistribution of giant cellsOlder ageLiver disease etiologyPrognostic factorsAdvanced fibrosisBetter survivalClinicopathological characteristicsLiver allografts
2022
Post-infantile Giant Cell Hepatitis: A Literature Review and Meta-analysis
Jiao J, Zhang X. Post-infantile Giant Cell Hepatitis: A Literature Review and Meta-analysis. Journal Of Clinical And Translational Pathology 2022, 2: 100-107. PMID: 37092012, PMCID: PMC10117396, DOI: 10.14218/jctp.2022.00016.Peer-Reviewed Original ResearchPost-infantile giant cell hepatitisDisease entityEtiological factorsAdditional etiological factorsGiant cell hepatitisRare disease entityVariable clinical courseGamma-glutamyl transferaseDiffuse distribution patternInterface hepatitisLobular inflammationPortal inflammationUncommon etiologyClinical courseEtiological distributionAutoimmune disordersPoor outcomeHistological featuresWorse outcomesTotal bilirubinMultifactorial etiologyBetter outcomesPatientsViral infectionMeta-Analysis