2023
AP-1–independent NFAT signaling maintains follicular T cell function in infection and autoimmunity
Seth A, Yokokura Y, Choi J, Shyer J, Vidyarthi A, Craft J. AP-1–independent NFAT signaling maintains follicular T cell function in infection and autoimmunity. Journal Of Experimental Medicine 2023, 220: e20211110. PMID: 36820828, PMCID: PMC9998660, DOI: 10.1084/jem.20211110.Peer-Reviewed Original ResearchConceptsTfh cellsT cellsFollicular helper T cellsLupus-prone miceT cell subsetsTfh cell developmentHelper T cellsHumoral immune responseT cell functionGerminal center B cellsT cell statesRenal injuryAutoantibody productionCell subsetsPrimary T cellsImmune responseB cellsPharmacologic inhibitionTherapeutic insightsCell functionGenetic disruptionNFATCell developmentCellsGene expression
2004
Age-associated changes in the frequency of naïve, memory and effector CD8+ T cells
Hong MS, Dan JM, Choi JY, Kang I. Age-associated changes in the frequency of naïve, memory and effector CD8+ T cells. Mechanisms Of Ageing And Development 2004, 125: 615-618. PMID: 15491679, DOI: 10.1016/j.mad.2004.07.001.Peer-Reviewed Original ResearchConceptsAge-associated changesT cell subsetsEffector CD8T cellsCell subsetsFrequencies of naïveFrequency of CD8Expression of CD45RAT cell functionEffector memoryPeripheral bloodCD8CM cellsDecreased frequencyCentral memoryFlow cytometryElderly peopleCell functionSimilar frequencyNaïveCellsCCR7CD45RABloodSubset