2015
The Yale Gastrointestinal Cancer Biorepository: A comprehensive biospecimen and data resource for studying determinants of pancreatic ductal adenocarcinoma prognosis following curative-intent pancreaticoduodenectomy.
Gould Rothberg BE, Deminie C, Lazowski H, Gibson J, Cha C, Lacy J, Hochster H, Salem R. The Yale Gastrointestinal Cancer Biorepository: A comprehensive biospecimen and data resource for studying determinants of pancreatic ductal adenocarcinoma prognosis following curative-intent pancreaticoduodenectomy. Journal Of Clinical Oncology 2015, 33: 272-272. DOI: 10.1200/jco.2015.33.3_suppl.272.Peer-Reviewed Original ResearchPancreatic ductal adenocarcinomaNeoadjuvant therapyCurative-intent pancreaticoduodenectomyDeterminants of outcomePancreatic ductal adenocarcinoma prognosisPDAC recurrenceMedical comorbiditiesIncident cancerSurgical resectionAdult patientsAdvanced cancerOncology clinicPDAC patientsVital statusGI cancersLifestyle factorsDuctal adenocarcinomaFamily historyPhysical activitySurgical pathologyPDAC prognosisTumor biologyBuffy coatCancerPatients
2014
Measurement of circulating tumor DNA as a cancer biomarker in gastrointestinal malignancies using a novel next-generation sequencing method.
James E, Narayan A, Stein S, Lacy J, Patel A, Hochster H. Measurement of circulating tumor DNA as a cancer biomarker in gastrointestinal malignancies using a novel next-generation sequencing method. Journal Of Clinical Oncology 2014, 32: 217-217. DOI: 10.1200/jco.2014.32.3_suppl.217.Peer-Reviewed Original ResearchGastrointestinal malignanciesMultiple time pointsTumor DNAAdvanced pancreatic cancerTime pointsCohort of patientsTumor DNA levelsChemo-radiation therapyMetastatic colon cancerAdjuvant settingCancer biomarkersMutant ctDNABevacizumab therapyTumor mutation profilesLiver metastasesGI tumorsGI cancersPancreatic cancerUltra-deep sequencingKRAS mutationsKRAS G12D mutationColon cancerAdditional longitudinal dataInformed consentLiquid biopsy