2014
Netrin-1 controls sympathetic arterial innervation
Brunet I, Gordon E, Han J, Cristofaro B, Broqueres-You D, Liu C, Bouvrée K, Zhang J, del Toro R, Mathivet T, Larrivée B, Jagu J, Pibouin-Fragner L, Pardanaud L, Machado MJ, Kennedy TE, Zhuang Z, Simons M, Levy BI, Tessier-Lavigne M, Grenz A, Eltzschig H, Eichmann A. Netrin-1 controls sympathetic arterial innervation. Journal Of Clinical Investigation 2014, 124: 3230-3240. PMID: 24937433, PMCID: PMC4071369, DOI: 10.1172/jci75181.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornDCC ReceptorFemaleGrowth ConesMaleMesenteric ArteriesMiceMice, KnockoutMice, Mutant StrainsMice, TransgenicModels, NeurologicalMyocytes, Smooth MuscleNerve Growth FactorsNetrin-1PregnancyReceptors, Cell SurfaceSympathetic Nervous SystemTumor Suppressor ProteinsVasoconstrictionConceptsSmooth muscle cellsArterial innervationNetrin-1Resistance arteriesAutonomic sympathetic nervesArterial smooth muscle cellsPeripheral resistance arteriesBlood flow regulationOnset of innervationBlood flow controlCell type-specific deletionAxon guidance cue netrin-1Guidance cue netrin-1Sympathetic nervesSympathetic innervationVascular toneColorectal cancerPeripheral organsSympathetic neuronsBlood supplyInnervationMuscle cellsSympathetic growth conesArteryGrowth cones
2008
Molecular Imaging of Activated Matrix Metalloproteinases in Vascular Remodeling
Zhang J, Nie L, Razavian M, Ahmed M, Dobrucki LW, Asadi A, Edwards DS, Azure M, Sinusas AJ, Sadeghi MM. Molecular Imaging of Activated Matrix Metalloproteinases in Vascular Remodeling. Circulation 2008, 118: 1953-1960. PMID: 18936327, PMCID: PMC2637824, DOI: 10.1161/circulationaha.108.789743.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, BalloonAnimalsApolipoproteins EAutoradiographyCarotid Artery InjuriesCarotid Artery, CommonDisease Models, AnimalFemaleFluorescent Antibody TechniqueIndiumMatrix Metalloproteinase 2Matrix Metalloproteinase 9MiceMice, Mutant StrainsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonConceptsVascular remodelingCarotid arteryCommon carotid artery injuryInjury-induced vascular remodelingCarotid wire injuryCarotid artery injuryMicroSPECT/CTMatrix metalloproteinase activationVessel wall areaArtery injuryCarotid injurySham surgerySignificant hyperplasiaContralateral arteryWire injuryFocal uptakeHyperplastic processesMicroSPECT imagingQuantitative autoradiographyTracer uptakeMetalloproteinase activationMMP activityArteryInjuryMatrix metalloproteinases