2014
Cosmetic side effects of antiepileptic drugs in adults with epilepsy
Chen B, Choi H, Hirsch L, Moeller J, Javed A, Kato K, Legge A, Buchsbaum R, Detyniecki K. Cosmetic side effects of antiepileptic drugs in adults with epilepsy. Epilepsy & Behavior 2014, 42: 129-137. PMID: 25513768, DOI: 10.1016/j.yebeh.2014.10.021.Peer-Reviewed Original ResearchConceptsCosmetic side effectsValproic acidSide effectsWeight gainGingival hyperplasiaHair lossPractice-based sampleMedication discontinuationAdult patientsDosage adjustmentFemale patientsNewer AEDsAntiepileptic drugsDifferent AEDsFemale sexMedical historyMedical recordsRisk factorsPhysician reportsAED usePatientsClinical practicePregabalinPatient recordsAEDs
2008
Lamotrigine–valproic acid combination therapy for medically refractory epilepsy
Moeller JJ, Rahey SR, Sadler RM. Lamotrigine–valproic acid combination therapy for medically refractory epilepsy. Epilepsia 2008, 50: 475-479. PMID: 19054403, DOI: 10.1111/j.1528-1167.2008.01866.x.Peer-Reviewed Original ResearchConceptsEpilepsy typeRefractory epilepsyAntiepileptic drugsCombination therapyPatient demographicsBaseline seizure frequencyRetrospective chart reviewPrimary outcome measureInclusion-exclusion criteriaVPA monotherapyChart reviewSeizure frequencyRetrospective studyMedical intractabilityClinic databaseUnimproved patientsOutcome measuresPatientsTherapyEpilepsyDemographicsSignificant differencesSeizuresMonthsSeverity