National Patterns of Use and Effectiveness of Angiotensin-Converting Enzyme Inhibitors in Older Patients With Heart Failure and Left Ventricular Systolic Dysfunction
Masoudi FA, Rathore SS, Wang Y, Havranek EP, Curtis JP, Foody JM, Krumholz HM. National Patterns of Use and Effectiveness of Angiotensin-Converting Enzyme Inhibitors in Older Patients With Heart Failure and Left Ventricular Systolic Dysfunction. Circulation 2004, 110: 724-731. PMID: 15289383, DOI: 10.1161/01.cir.0000138934.28340.ed.Peer-Reviewed Original ResearchConceptsACE inhibitor prescriptionAngiotensin receptor blockersVentricular systolic dysfunctionHeart failureACE inhibitorsInhibitor prescriptionSystolic dysfunctionOlder patientsLeft ventricular systolic dysfunctionAngiotensin converting enzyme (ACE) inhibitorsSerum creatinine levelsACE inhibitor useCreatinine levelsHospital factorsInhibitor useReceptor blockersSerum creatininePatient genderClinical trialsTherapeutic substitutionLower riskEnzyme inhibitorsLower mortalityPatientsSecondary analysisAssociation Between Functional Status and Use and Effectiveness of Beta‐Blocker Prophylaxis in Elderly Survivors of Acute Myocardial Infarction
Vitagliano G, Curtis JP, Concato J, Feinstein AR, Radford MJ, Krumholz HM. Association Between Functional Status and Use and Effectiveness of Beta‐Blocker Prophylaxis in Elderly Survivors of Acute Myocardial Infarction. Journal Of The American Geriatrics Society 2004, 52: 495-501. PMID: 15066062, DOI: 10.1111/j.1532-5415.2004.52153.x.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAcute DiseaseAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overCross-Sectional StudiesDrug PrescriptionsDrug UtilizationFemaleGeriatric AssessmentHumansLogistic ModelsMaleMultivariate AnalysisMyocardial InfarctionPatient DischargePatient SelectionPractice Patterns, Physicians'Proportional Hazards ModelsRetrospective StudiesSurvival AnalysisTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionHospital dischargeFunctional impairmentElderly patientsMyocardial infarctionAcute myocardial infarction survivorsBeta-blocker prescriptionBeta-blocker prophylaxisBeta-blocker treatmentRetrospective cohort studySimilar survival benefitMain outcome measuresMyocardial infarction survivorsAcute care hospitalsEligible patientsCohort studySurvival benefitCare hospitalFunctional statusNational cohortInfarction survivorsOutcome measuresElderly survivorsPatientsCognitive impairment