2023
Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes
Chui P, Lan Z, Freeman J, Enriquez A, Khera R, Akar J, Masoudi F, Ong E, Curtis J. Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes. Heart Rhythm 2023, 20: 1000-1008. PMID: 36963741, DOI: 10.1016/j.hrthm.2023.03.022.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac Resynchronization TherapyDefibrillators, ImplantableHeart FailureHospitalsHumansMedicareTreatment OutcomeUnited StatesConceptsEligible patientsICD RegistryCardiac resynchronizationNational Cardiovascular Data Registry ICD RegistryCRT-D implantationCRT-D useHospital-level outcomesStrong guideline recommendationsHospital-level variationPatient-level outcomesIntraclass correlation coefficientQuality improvement effortsHospital mortalityGuideline indicationsReadmission ratesSelect patientsClinical outcomesGuideline recommendationsHospital variationHospital ratesUse of CRTHospital levelHospital usePatientsCase mix
2022
Survival Probability and Survival Benefit Associated With Primary Prevention Implantable Cardioverter‐Defibrillator Generator Changes
Bilchick KC, Wang Y, Curtis JP, Shadman R, Dardas TF, Anand I, Lund LH, Dahlström U, Sartipy U, Levy WC. Survival Probability and Survival Benefit Associated With Primary Prevention Implantable Cardioverter‐Defibrillator Generator Changes. Journal Of The American Heart Association 2022, 11: e023743. PMID: 35766293, PMCID: PMC9333379, DOI: 10.1161/jaha.121.023743.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure modelHeart failure patientsResynchronization therapyGenerator changeSurvival benefitWorse survivalFailure patientsNational Cardiovascular Data Registry ICD RegistryGC survivalSurvival Benefit AssociatedPrimary prevention indicationVentricular ejection fractionAnnual mortalityICD therapyConclusions PatientsPrevention indicationEjection fractionICD RegistryImproved survivalPrimary preventionPatient deathGreater effect sizeLVEFPatientsLongitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients
Friedman DJ, Qin L, Parzynski C, Heist EK, Russo AM, Ranasinghe I, Zeitler EP, Minges KE, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM. Longitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients. Journal Of The American College Of Cardiology 2022, 79: 1050-1059. PMID: 35300816, DOI: 10.1016/j.jacc.2021.12.033.Peer-Reviewed Original ResearchMeSH KeywordsAgedArrhythmias, CardiacDeath, Sudden, CardiacDefibrillators, ImplantableFemaleHumansMaleMedicareRetrospective StudiesTreatment OutcomeUnited StatesConceptsOlder patientsCause readmissionS-ICDNational Cardiovascular Data Registry ICD RegistryDevice removalTransvenous implantable cardioverter defibrillatorTV-ICD patientsRisk of deathS-ICD patientsService Medicare beneficiariesAnderson-Gill modelsImplantable cardioverter defibrillatorRepresentative national cohortCompeting-risks modelTV-ICDCardiovascular readmissionCause mortalityICD implantationYounger patientsICD RegistryNonfatal outcomesTransvenous ICDAtrial fibrillationNational cohortCardioverter defibrillatorTrends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018
Borne RT, Varosy P, Lan Z, Masoudi FA, Curtis JP, Matlock DD, Peterson PN. Trends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018. JAMA Network Open 2022, 5: e223429. PMID: 35315917, PMCID: PMC8941353, DOI: 10.1001/jamanetworkopen.2022.3429.Peer-Reviewed Original ResearchMeSH KeywordsAtrial FibrillationCardiac Resynchronization TherapyCross-Sectional StudiesDefibrillators, ImplantableHumansMaleMiddle AgedRegistriesConceptsDual-chamber ICDFirst-time ICD implantationPacing indicationICD implantationMedian odds ratioPatient characteristicsOdds ratioAtrial leadNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy indicationDual-chamber ICD implantationMulticenter cross-sectional studyBradycardia pacing indicationSingle-chamber ICDHospital-level variationHigh procedural riskCross-sectional studyLow-value practicesImplantable cardioverter defibrillatorLow-value careCochran-Armitage trend testImplantable cardioverter-defibrillator systemsDual-chamber devicesCardioverter-defibrillator systemsReal-world practiceHospital Characteristics and Early Enrollment Trends in the American College of Cardiology Voluntary Public Reporting Program
Castro-Dominguez YS, Curtis JP, Masoudi FA, Wang Y, Messenger JC, Desai NR, Slattery LE, Dehmer GJ, Minges KE. Hospital Characteristics and Early Enrollment Trends in the American College of Cardiology Voluntary Public Reporting Program. JAMA Network Open 2022, 5: e2147903. PMID: 35142829, PMCID: PMC8832180, DOI: 10.1001/jamanetworkopen.2021.47903.Peer-Reviewed Original ResearchMeSH KeywordsCardiac CatheterizationCardiologyCross-Sectional StudiesDefibrillators, ImplantableFemaleForecastingHospitalsHumansMalePercutaneous Coronary InterventionResearch DesignUnited StatesConceptsPublic reporting programsHospital characteristicsCharacteristics of hospitalsEligible hospitalsAmerican CollegeNational Cardiovascular Data Registry CathPCIReporting ProgramHospital rankingsHospital 1 monthCross-sectional studyQuality of careStepwise logistic regressionOdds of participationCoronary interventionDischarge medicationsHospital factorsICD RegistryLarge hospital systemNonparticipating hospitalsProcedural volumeMAIN OUTCOMEHospitalLogistic regressionProcedure dataHospital system
2021
Risk and predictors of mortality after implantable cardioverter-defibrillator implantation in patients with sarcoid cardiomyopathy
Higgins AY, Annapureddy AR, Wang Y, Minges KE, Bellumkonda L, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Risk and predictors of mortality after implantable cardioverter-defibrillator implantation in patients with sarcoid cardiomyopathy. American Heart Journal 2021, 246: 21-31. PMID: 34968442, DOI: 10.1016/j.ahj.2021.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAtrial FibrillationDeath, Sudden, CardiacDefibrillators, ImplantableHeart FailureHumansMyocarditisRetrospective StudiesRisk FactorsSarcoidosisStroke VolumeVentricular Function, LeftConceptsNon-ischemic cardiomyopathyAtrial fibrillation/flutterChronic lung diseaseCardiac sarcoidosisHeart failureCS patientsNICM patientsICD implantationLung diseaseNew York Heart Association class III heart failureNational Cardiovascular Data Registry ICD RegistryNYHA class IV heart failureClass III heart failureClass IV heart failureImplantable cardioverter defibrillator implantationKaplan-Meier survival curvesCox proportional hazards modelPredictors of mortalityCardioverter-defibrillator implantationVentricular ejection fractionMultivariable logistic regressionPrior ventricular arrhythmiasProportional hazards modelRate of deathTime of implantationTrends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation
Bourdillon PM, Parzynski CS, Minges KE, Curtis JP, Desai NR. Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation. Journal Of Cardiac Failure 2021, 28: 154-160. PMID: 34628015, DOI: 10.1016/j.cardfail.2021.09.010.Peer-Reviewed Original ResearchMeSH KeywordsAgedDeath, Sudden, CardiacDefibrillators, ImplantableHeart FailureHospitalsHumansMedicareMyocardial InfarctionPrimary PreventionRegistriesUnited StatesConceptsHospital adverse eventsHospital outcomesAdverse eventsHeart failureMyocardial infarctionRecent acute myocardial infarctionPlacement of ICDsPrimary prevention ICDsAdverse event ratesRecent myocardial infarctionAcute myocardial infarctionHigh mortality rateICD implantationRecent diagnosisMortality ratePatientsICDInfarctionHospitalOutcomesRapid reductionUse of devicesFailureSpecific reasonsCriteriaComparative outcomes of Riata and Fidelis lead management strategies: Results from the NCDR‐ICD Registry
Zeitler EP, Wang Y, Pokorney SD, Curtis J, Prutkin JM. Comparative outcomes of Riata and Fidelis lead management strategies: Results from the NCDR‐ICD Registry. Pacing And Clinical Electrophysiology 2021, 44: 1897-1906. PMID: 34520564, DOI: 10.1111/pace.14361.Peer-Reviewed Original ResearchMeSH KeywordsAgedDefibrillators, ImplantableElectrodes, ImplantedEquipment DesignEquipment FailureFemaleHumansMaleMiddle AgedRegistriesConceptsPre-discharge complicationsNCDR ICD RegistryExtraction groupGenerator replacementElective generator changeGenerator replacement proceduresLead dwell timeMedtronic Sprint FidelisPeri-procedural riskOdds of deathLong-term outcomesMulti-centre populationElective generator replacementReal-world populationLead management strategiesHospital complicationsHospital mortalityICD RegistryTerm outcomesSprint FidelisAdjusted ratesComparative outcomesExtraction patientsComplicationsICD leadLongitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry)
Daimee UA, Aslam F, Parzynski CS, Desai NR, Curtis JP. Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry). The American Journal Of Cardiology 2021, 155: 64-71. PMID: 34315569, DOI: 10.1016/j.amjcard.2021.06.020.Peer-Reviewed Original ResearchConceptsPrimary prevention ICD implantationRisk of mortalityICD implantationHeart failureICD RegistryMortality riskNational Cardiovascular Data Registry ICD RegistryPivotal randomized clinical trialsHospital adverse eventsSevere heart failureRecent myocardial infarctionCause hospital readmissionRandomized clinical trialsSimilar mortality riskLongitudinal outcomesImplantable cardioverter defibrillatorGreater mortality riskCause hospitalizationCause mortalityCoronary revascularizationAdverse eventsHospital readmissionICD recipientsDevice implantationPrimary preventionDefibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR. JACC Clinical Electrophysiology 2021, 7: 1145-1154. PMID: 33933411, DOI: 10.1016/j.jacep.2021.02.019.Peer-Reviewed Original ResearchMeSH KeywordsDefibrillators, ImplantableHeart Defects, CongenitalHospital MortalityHumansRegistriesRetrospective StudiesConceptsCongenital heart diseaseLowest successful energyHospital stayNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator insertionVentricular septal defectTetralogy of FallotHeart disease resultHospital complicationsHospital deathHospital outcomesMultivariable adjustmentEbstein's anomalyICD RegistryICD recipientsSeptal defectCommon ventricleHeart diseaseRetrospective analysisLower oddsGreat vesselsICD proceduresDisease resultsSuccessful energyICD generatorImpact of insurance status on ICD implantation practice patterns: Insights from the NCDR ICD registry
Ahmed I, Merchant FM, Curtis JP, Parzynski CS, Lampert R. Impact of insurance status on ICD implantation practice patterns: Insights from the NCDR ICD registry. American Heart Journal 2021, 235: 44-53. PMID: 33503408, DOI: 10.1016/j.ahj.2021.01.016.Peer-Reviewed Original ResearchMeSH KeywordsDeath, Sudden, CardiacDefibrillators, ImplantableFemaleHeart FailureHumansInsurance CoverageMaleMiddle AgedPrimary PreventionRegistriesRetrospective StudiesConceptsOptimal medical therapyInsurance statusNCDR ICD RegistryMedical therapyComplication rateICD RegistryUninsured patientsCardiac resynchronization therapy defibrillatorPrivate insurancePropensity-weighted analysisSingle-chamber devicesPrimary preventionMean ageICD implantsPractice patternsTreatment weightingImplantation practicePatientsInverse probabilityTherapyInsurance coverageFurther studiesRegistryMedicareStatusUse and Outcomes of Dual Chamber or Cardiac Resynchronization Therapy Defibrillators Among Older Patients Requiring Ventricular Pacing in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Borne RT, Masoudi FA, Curtis JP, Zipse MM, Sandhu A, Hsu JC, Peterson PN. Use and Outcomes of Dual Chamber or Cardiac Resynchronization Therapy Defibrillators Among Older Patients Requiring Ventricular Pacing in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Network Open 2021, 4: e2035470. PMID: 33496796, PMCID: PMC7838925, DOI: 10.1001/jamanetworkopen.2020.35470.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyHeart failure hospitalizationClass I indicationsUse of CRTFailure hospitalizationMedian odds ratioCohort studyOlder patientsVentricular pacingImplant ratesNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryNational Cardiovascular Data Registry ICD RegistryReduced left ventricular ejection fractionMultivariable Cox proportional hazards modelsFrequent right ventricular pacingImplantable Cardioverter-Defibrillator RegistryPrior heart failure hospitalizationLeft ventricular ejection fractionImplantable cardioverter defibrillator implantationThird-degree atrioventricular blockCardiac resynchronization therapy defibrillatorCox proportional hazards modelBradycardia pacing indicationFirst-time implantationFrequent RV pacing
2020
Association Between Industry Payments to Physicians and Device Selection in ICD Implantation
Annapureddy AR, Henien S, Wang Y, Minges KE, Ross JS, Spatz ES, Desai NR, Peterson PN, Masoudi FA, Curtis JP. Association Between Industry Payments to Physicians and Device Selection in ICD Implantation. JAMA 2020, 324: 1755-1764. PMID: 33141208, PMCID: PMC7610190, DOI: 10.1001/jama.2020.17436.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac Resynchronization Therapy DevicesCross-Sectional StudiesDefibrillators, ImplantableFemaleHumansIncomeMaleManufacturing IndustryPhysiciansRegistriesConceptsCRT-D implantationCRT-D devicesCross-sectional studyNational Cardiovascular Data Registry ICD RegistryFirst-time ICDFirst-time implantationProportion of patientsEntire study cohortDevice selectionProportion of devicesICD implantationICD RegistryPrimary outcomeCardiac resynchronizationStudy cohortPatient groupMAIN OUTCOMEPatientsPhysiciansICDAbsolute differenceImplantationManufacturer CHigher total paymentsAssociationTrends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis
Pun PH, Parzynski CS, Friedman DJ, Sanders G, Curtis JP, Al-Khatib SM. Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis. Clinical Journal Of The American Society Of Nephrology 2020, 15: 1622-1630. PMID: 32967922, PMCID: PMC7646229, DOI: 10.2215/cjn.07920520.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestSubcutaneous ICDTransvenous ICDICD implantsHospital outcomesICD recipientsICD RegistryCardiac arrestHigh riskNational Cardiovascular Data Registry ICD RegistryFirst-time ICD recipientsPropensity score-weighted analysisImplantable cardioverter defibrillator implantationSubcutaneous implantable cardioverter defibrillatorIn-Hospital OutcomesShort-term complicationsCardioverter-defibrillator implantationLong-term dialysisVascular access siteImplantable cardioverter defibrillatorCause deathHospital complicationsHospital stayDefibrillator implantationUS patientsSurvival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy
Higgins AY, Annapureddy AR, Wang Y, Minges KE, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Survival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016038. PMID: 32867553, PMCID: PMC7726970, DOI: 10.1161/jaha.120.016038.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmyloidosisCardiomyopathiesCase-Control StudiesDefibrillators, ImplantableFemaleHumansMaleMiddle AgedProsthesis ImplantationRegistriesRetrospective StudiesConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationNonischemic cardiomyopathyCardiac amyloidosisDiabetes mellitusCerebrovascular diseaseVentricular tachycardiaMultivariable Cox proportional hazards regression modelsCox proportional hazards regression modelProportional hazards regression modelsKaplan-Meier survival curvesCox proportional hazards modelPropensity-matched cohortOutcomes of patientsHazards regression modelsProportional hazards modelCause mortalityICD implantationRenal functionMultivariable analysisConclusions MortalityRisk factorsRegistry dataAmyloid cardiomyopathyHigh riskComparison of Mortality and Readmission in Non-Ischemic Versus Ischemic Cardiomyopathy After Implantable Cardioverter-Defibrillator Implantation
Higgins AY, Bjerre J, Parzynski CS, Minges KE, Ahmad T, Desai NR, Enriquez A, Spatz ES, Friedman DJ, Curtis JP, Hlatky MA, Freeman JV. Comparison of Mortality and Readmission in Non-Ischemic Versus Ischemic Cardiomyopathy After Implantable Cardioverter-Defibrillator Implantation. The American Journal Of Cardiology 2020, 133: 116-125. PMID: 32862971, DOI: 10.1016/j.amjcard.2020.07.035.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiomyopathiesDefibrillators, ImplantableFemaleHumansMaleMiddle AgedMyocardial IschemiaPatient ReadmissionRegistriesRetrospective StudiesSurvival RateUnited StatesConceptsNon-ischemic cardiomyopathyImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationICM patientsIschemic cardiomyopathyNational Cardiovascular Data Registry ICD RegistryCox proportional hazards regression modelPrimary prevention ICD implantationLeft ventricular ejection fractionProportional hazards regression modelsPrimary prevention ICDsRetrospective cohort studyVentricular ejection fractionKaplan-Meier curvesHazards regression modelsRisk of mortalityComparison of mortalityMedian followCohort studyICD implantationEjection fractionHeart failureHospital readmissionICD RegistryPatient subgroupsPeriprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure
Fudim M, Ali-Ahmed F, Parzynski CS, Ambrosy AP, Friedman DJ, Pokorney SD, Curtis JP, Fonarow GC, Masoudi FA, Hernandez AF, Al-Khatib SM. Periprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure. JAMA Cardiology 2020, 5: 643-651. PMID: 32211811, PMCID: PMC7097837, DOI: 10.1001/jamacardio.2020.0391.Peer-Reviewed Original ResearchConceptsAdvanced heart failureAdvanced HF populationHeart transplant listingPeriprocedural complication rateHeart failureSudden cardiac deathComparator groupVentricular assist deviceInotrope useTransplant listingCardiac deathComplication rateHF populationPrimary preventionCardiac arrestNew York Heart Association class IV symptomsNational Cardiovascular Data Registry ICD RegistryAssist deviceLeft ventricular ejection fractionImplantable cardioverter-defibrillator placementAdvanced HF groupClass IV symptomsFirst-time ICDLeft ventricular assist deviceNYHA class IIComparison of left ventricular lead upgrade vs continued medical care among patients eligible for cardiac resynchronization therapy at the time of defibrillator generator replacement: Predictors of left ventricular lead upgrade and associations with long-term outcomes
Hyman MC, Bao H, Curtis JP, Minges K, Schaller RD, Birgersdotter-Green U, Marchlinski FE, Hsu JC. Comparison of left ventricular lead upgrade vs continued medical care among patients eligible for cardiac resynchronization therapy at the time of defibrillator generator replacement: Predictors of left ventricular lead upgrade and associations with long-term outcomes. Heart Rhythm 2020, 17: 1878-1886. PMID: 32497762, DOI: 10.1016/j.hrthm.2020.05.032.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac Resynchronization TherapyDefibrillators, ImplantableFemaleFollow-Up StudiesHeart FailureHeart VentriclesHumansMaleRegistriesRetrospective StudiesTreatment OutcomeConceptsCardiac resynchronization therapyCRT-eligible patientsCRT upgradeResynchronization therapyClinical outcomesNational Cardiovascular Data Registry ICD RegistryGenerator replacementPeriprocedural complication rateLeft ventricular leadSubpopulation of patientsLong-term outcomesICD generator replacementHierarchical logistic regression modelsLogistic regression modelsSecondary endpointsCause mortalityPrimary endpointComplication rateICD RegistryProcedural complicationsMedical managementICD populationNational registryVentricular leadClaims dataUtilization Effects of the Affordable Care Act on Implantable Cardioverter-Defibrillator Therapy
Madias C, Parzynski CS, Burrows A, Minges KE, Curtis JP, Doukky R. Utilization Effects of the Affordable Care Act on Implantable Cardioverter-Defibrillator Therapy. Journal Of The American College Of Cardiology 2020, 75: 1714-1717. PMID: 32273036, DOI: 10.1016/j.jacc.2020.02.023.Peer-Reviewed Original ResearchPrevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Prevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR. International Journal Of Cardiology 2020, 305: 44-49. PMID: 31980272, DOI: 10.1016/j.ijcard.2020.01.027.Peer-Reviewed Original ResearchMeSH KeywordsChildDefibrillators, ImplantableElectric CountershockHumansLength of StayPrevalenceRegistriesRetrospective StudiesVentricular FibrillationConceptsInadequate defibrillation safety marginDefibrillation safety marginDFT testingDefibrillation threshold testingHospital complicationsPediatric patientsHospital stayICD recipientsNational Cardiovascular Data Registry ICD RegistryThreshold testingLowest successful energyProlonged hospital stayRisk of complicationsTransvenous ICD implantationHospital dischargeICD implantationMultivariable adjustmentICD RegistryPediatric populationRetrospective analysisLower oddsComplicationsPatientsTesting useLittle data