Prevalence and Predictors of Off-Label Use of Cardiac Resynchronization Therapy in Patients Enrolled in the National Cardiovascular Data Registry Implantable Cardiac-Defibrillator Registry
Fein AS, Wang Y, Curtis JP, Masoudi FA, Varosy PD, Reynolds MR, Registry C. Prevalence and Predictors of Off-Label Use of Cardiac Resynchronization Therapy in Patients Enrolled in the National Cardiovascular Data Registry Implantable Cardiac-Defibrillator Registry. Journal Of The American College Of Cardiology 2010, 56: 766-773. PMID: 20797489, PMCID: PMC2958057, DOI: 10.1016/j.jacc.2010.05.025.Peer-Reviewed Original ResearchConceptsNew York Heart Association functional classYork Heart Association functional classQRS interval durationLabel useConsensus guidelinesMultivariable hierarchical logistic regression modelsPrevious percutaneous coronary interventionAtrial fibrillation/flutterEvidence-based consensus guidelinesFunctional classGuideline-based indicationsPrimary prevention indicationCardiac resynchronization therapyPercutaneous coronary interventionOff-label useHierarchical logistic regression modelsInterval durationLogistic regression modelsStudy time frameApplication of CRTCoronary interventionPrevention indicationDiabetes mellitusEjection fractionResynchronization therapy